(Q79460774)

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Inhibition of histone deacetylation promotes abnormal epidermal differentiation and specifically suppresses the expression of the late differentiation marker profilaggrin

scientific article published on 28 December 2006

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17195011%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

Inhibition of histone deacetylation promotes abnormal epidermal differentiation and specifically suppresses the expression of the late differentiation marker profilaggrin (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17195011%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

author name string

Nelli G Markova

1

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23 December 2019

Nevena Karaman-Jurukovska

2

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23 December 2019

Adriana Pinkas-Sarafova

3

1 reference

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23 December 2019

Liuben N Marekov

4

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23 December 2019

Marcia Simon

5

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23 December 2019

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28 December 2006

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23 December 2019

Journal of Investigative Dermatology

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17195011%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

127

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23 December 2019

5

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Europe PubMed Central

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23 December 2019

1126-1139

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23 December 2019

https://scigraph.springernature.com/pub.10.1038/sj.jid.5700684

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Transcription factor Sp3 is regulated by acetylation

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Histone hyperacetylation induced by histone deacetylase inhibitors is not sufficient to cause growth inhibition in human dermal fibroblasts

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Coordinate changes in gene expression which mark the spinous to granular cell transition in epidermis are regulated by protein kinase C.

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Trichostatin A induces transforming growth factor beta type II receptor promoter activity and acetylation of Sp1 by recruitment of PCAF/p300 to a Sp1.NF-Y complex

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Stable histone deacetylase complexes distinguished by the presence of SANT domain proteins CoREST/kiaa0071 and Mta-L1

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The transglutaminase 1 enzyme is variably acylated by myristate and palmitate during differentiation in epidermal keratinocytes

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Complex interactions between epidermal POU domain and activator protein 1 transcription factors regulate the expression of the profilaggrin gene in normal human epidermal keratinocytes

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The paradox of histone deacetylase inhibitor-mediated modulation of cellular responses to radiation.

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Roles of histone acetyltransferases and deacetylases in gene regulation

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Analysis of histone subtypes and their modified forms by polyacrylamide gel electrophoresis

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Corepressor-dependent silencing of chromosomal regions encoding neuronal genes

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Histone deacetylase inhibitors

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Reduced stability and bi-allelic, coequal expression of profilaggrin mRNA in keratinocytes cultured from subjects with ichthyosis vulgaris

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