(Q79749964)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17289815%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

review article

1 reference

title

New thrombopoietic growth factors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17289815%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

author name string

David J Kuter

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17289815%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

publication date

8 February 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17289815%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17289815%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

volume

109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17289815%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

page(s)

4607-4616

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17289815%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17289815%20AND%20SRC:MED&resulttype=core&format=json

Dose-response effects of pegylated human megakaryocyte growth and development factor on platelet production and function in nonhuman primates

25 December 2019

cites work

1 reference

12 December 2020

Effects of polyethylene glycol-conjugated recombinant human megakaryocyte growth and development factor on platelet counts after chemotherapy for lung cancer

1 reference

12 December 2020

Phase 1 study of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) in breast cancer patients after autologous peripheral blood progenitor cell (PBPC) transplantation.

1 reference

12 December 2020

Enhancement of platelet recovery after myelosuppressive chemotherapy by recombinant human megakaryocyte growth and development factor in patients with advanced cancer

1 reference

12 December 2020

Thrombopoietin therapy increases platelet yields in healthy platelet donors

1 reference

12 December 2020

Prophylactic platelet transfusions from healthy apheresis platelet donors undergoing treatment with thrombopoietin

1 reference

12 December 2020

Hydrazinonaphthalene and azonaphthalene thrombopoietin mimics are nonpeptidyl promoters of megakaryocytopoiesis

1 reference

12 December 2020

Thrombocytopenia caused by the development of antibodies to thrombopoietin

1 reference

12 December 2020

Cyclic immune thrombocytopenia responsive to thrombopoietic growth factor therapy

1 reference

12 December 2020

Development of pancytopenia with neutralizing antibodies to thrombopoietin after multicycle chemotherapy supported by megakaryocyte growth and development factor

1 reference

12 December 2020

Thrombopoietin administered during induction chemotherapy to patients with acute myeloid leukemia induces transient morphologic changes that may resemble chronic myeloproliferative disorders

1 reference

12 December 2020

Effects of pegylated recombinant human megakaryocyte growth and development factor in patients with idiopathic thrombocytopenic purpura

1 reference

12 December 2020

Safety and efficacy of transfusions of autologous cryopreserved platelets derived from recombinant human thrombopoietin to support chemotherapy-associated severe thrombocytopenia: a randomised cross-over study.

1 reference

12 December 2020

Identification of a pharmacophore for thrombopoietic activity of small, non-peptidyl molecules. 1. Discovery and optimization of salicylaldehyde thiosemicarbazone thrombopoietin mimics.

1 reference

12 December 2020

Stimulation of megakaryocyte and platelet production by a single dose of recombinant human thrombopoietin in patients with cancer

1 reference

12 December 2020

Randomized, blinded, placebo-controlled phase I trial of pegylated recombinant human megakaryocyte growth and development factor with filgrastim after dose-intensive chemotherapy in patients with advanced cancer

1 reference

12 December 2020

Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine

1 reference

12 December 2020

Is inadequate thrombopoietin production a major cause of thrombocytopenia in cirrhosis of the liver?

1 reference

12 December 2020

High thrombopoietin production by hematopoietic cells induces a fatal myeloproliferative syndrome in mice

1 reference

12 December 2020

The role of transforming growth factor-beta in PEG-rHuMGDF-induced reversible myelofibrosis in rats

1 reference

12 December 2020

Adenovector-mediated expression of human thrombopoietin cDNA in immune-compromised mice: insights into the pathophysiology of osteomyelofibrosis.

1 reference

12 December 2020

Platelets in thrombotic disorders: quantitative and qualitative platelet disorders predisposing to arterial thrombosis

1 reference

12 December 2020

Primary role of the liver in thrombopoietin production shown by tissue-specific knockout

1 reference

12 December 2020

Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation

1 reference

12 December 2020

Erythropoietin receptor activation by a ligand-induced conformation change

1 reference

12 December 2020

Recombinant human thrombopoietin in combination with granulocyte colony-stimulating factor enhances mobilization of peripheral blood progenitor cells, increases peripheral blood platelet concentration, and accelerates hematopoietic recovery followin

1 reference

12 December 2020

Human platelets display high-affinity receptors for thrombopoietin

1 reference

12 December 2020

Human platelets as a model for the binding and degradation of thrombopoietin

1 reference

12 December 2020

Recombinant human thrombopoietin attenuates carboplatin-induced severe thrombocytopenia and the need for platelet transfusions in patients with gynecologic cancer.

1 reference

12 December 2020

A phase I trial of recombinant human thrombopoietin in patients with delayed platelet recovery after hematopoietic stem cell transplantation

1 reference

12 December 2020

A double-blind, placebo-controlled trial of pegylated recombinant human megakaryocyte growth and development factor as an adjunct to induction and consolidation therapy for patients with acute myeloid leukemia

1 reference

12 December 2020

Biologic and structural differences of thrombopoietic growth factors

1 reference

12 December 2020

Deletion of the extracellular membrane-distal cytokine receptor homology module of Mpl results in constitutive cell growth and loss of thrombopoietin binding.

1 reference

12 December 2020

Immunogenicity of thrombopoietin mimetic peptide GW395058 in BALB/c mice and New Zealand white rabbits: evaluation of the potential for thrombopoietin neutralizing antibody production in man.

1 reference

12 December 2020

Interaction of thrombopoietin with the platelet c-mpl receptor in plasma: binding, internalization, stability and pharmacokinetics

1 reference

12 December 2020

Pharmacodynamics and pharmacokinetics of AMG 531, a novel thrombopoietin receptor ligand

1 reference

12 December 2020

A novel therapeutic approach for thrombocytopenia by minibody agonist of the thrombopoietin receptor

1 reference

12 December 2020

Discovery and characterization of a selective, nonpeptidyl thrombopoietin receptor agonist.

1 reference

12 December 2020

New benzimidazoles as thrombopoietin receptor agonists.

1 reference

12 December 2020

A rationally designed agonist antibody fragment that functionally mimics thrombopoietin

1 reference

12 December 2020

AKR-501 (YM477) a novel orally-active thrombopoietin receptor agonist

1 reference

12 December 2020

A randomized, double-blind, placebo-controlled study with pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) as an adjunct to chemotherapy for adults with de novo acute myeloid leukemia

1 reference

12 December 2020

Thrombopoietin induces rapid resolution of thrombocytopenia after orthotopic liver transplantation through increased platelet production.

1 reference

12 December 2020

Identification of a pharmacophore for thrombopoietic activity of small, non-peptidyl molecules. 2. Rational design of naphtho[1,2-d]imidazole thrombopoietin mimics

1 reference

12 December 2020

The effects of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) on platelet recovery in breast cancer patients undergoing autologous bone marrow transplantation

1 reference

12 December 2020

Recombinant human thrombopoietin: basic biology and evaluation of clinical studies

1 reference

12 December 2020

AMG531 stimulates megakaryopoiesis in vitro by binding to Mpl.

1 reference

12 December 2020

Structure of the receptor-binding domain of human thrombopoietin determined by complexation with a neutralizing antibody fragment

1 reference

12 December 2020

The effect of massive liver resection on platelet kinetics in the rat

1 reference

12 December 2020

Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand.

1 reference

12 December 2020

Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo

1 reference

12 December 2020

Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl.

1 reference

12 December 2020

Appearance of a megakaryocyte growth-promoting activity, megapoietin, during acute thrombocytopenia in the rabbit

1 reference

12 December 2020

The purification of megapoietin: a physiological regulator of megakaryocyte growth and platelet production

1 reference

12 December 2020

Distinct regions of c-Mpl cytoplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation

1 reference

12 December 2020

Thrombopoietin receptor expression in human cancer cell lines and primary tissues.

1 reference

12 December 2020

Purification and characterization of thrombopoietin

1 reference

12 December 2020

Accelerated reconstitution of platelets and erythrocytes after syngeneic transplantation of bone marrow cells derived from thrombopoietin pretreated donor mice

1 reference

12 December 2020

Chronic exposure to retroviral vector encoded MGDF (mpl-ligand) induces lineage-specific growth and differentiation of megakaryocytes in mice.

1 reference

12 December 2020

Point mutations within a dimer interface homology domain of c-Mpl induce constitutive receptor activity and tumorigenicity

1 reference

12 December 2020

Thrombopoietin in thrombocytopenic mice: evidence against regulation at the mRNA level and for a direct regulatory role of platelets

1 reference

12 December 2020

Regulation of platelet production and function by megakaryocyte growth and development factor in nonhuman primates

1 reference

12 December 2020

Regulation of thrombopoietin levels by c-mpl-mediated binding to platelets

1 reference

12 December 2020

Relative reactivity of platelets from thrombopoietin- and interleukin-6-treated dogs

1 reference

12 December 2020

Systemic hematologic effects of PEG-rHuMGDF-induced megakaryocyte hyperplasia in mice.

1 reference

12 December 2020

A model of myelofibrosis and osteosclerosis in mice induced by overexpressing thrombopoietin (mpl ligand): reversal of disease by bone marrow transplantation.

1 reference

12 December 2020

10.1182/BLOOD-2006-10-019315

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17289815%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17289815%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference