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TLR9 signaling is essential for the innate NK cell response in murine cutaneous leishmaniasis
scientific article published on 01 December 2007
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18034422
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18034422%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
title
TLR9 signaling is essential for the innate NK cell response in murine cutaneous leishmaniasis
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18034422
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18034422%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
main subject
cutaneous leishmaniasis
1 reference
based on heuristic
inferred from title
author
Christian Bogdan
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18034422
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18034422%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
author name string
Jan Liese
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18034422
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18034422%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
Ulrike Schleicher
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18034422
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18034422%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
publication date
1 December 2007
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18034422
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18034422%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
published in
European Journal of Immunology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18034422
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18034422%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
volume
37
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18034422
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18034422%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
issue
12
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18034422
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18034422%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
page(s)
3424-3434
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18034422
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18034422%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
cites work
Cytokines in leishmaniasis: a complex network of stimulatory and inhibitory interactions.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The immune response to Leishmania: mechanisms of parasite control and evasion.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The host response to Leishmania infection.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rapidly fatal leishmaniasis in resistant C57BL/6 mice lacking TNF.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The immunology of susceptibility and resistance to Leishmania major in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD4+ effector cells default to the Th2 pathway in interferon gamma-deficient mice infected with Leishmania major
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IL-4 Rapidly Produced by Vβ4 Vα8 CD4+ T Cells Instructs Th2 Development and Susceptibility to Leishmania major in BALB/c Mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Natural killer cells are a source of interferon gamma that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Natural killer cells participate in the early defense against Leishmania major infection in mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early parasite containment is decisive for resistance to Leishmania major infection.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Type 1 interferon (IFNalpha/beta) and type 2 nitric oxide synthase regulate the innate immune response to a protozoan parasite
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of Leishmania major in the absence of Tyk2 kinase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Natural killer cell behavior in lymph nodes revealed by static and real-time imaging.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MyD88 is essential for clearance of Leishmania major: possible role for lipophosphoglycan and Toll‐like receptor 2 signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High levels of susceptibility and T helper 2 response in MyD88-deficient mice infected with Leishmania major are interleukin-4 dependent
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetically Resistant Mice Lacking MyD88-Adapter Protein Display a High Susceptibility to Leishmania major Infection Associated with a Polarized Th2 Response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Toll-like receptor 4 contributes to efficient control of infection with the protozoan parasite Leishmania major
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The immunobiology of the TLR9 subfamily
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA from protozoan parasites Babesia bovis, Trypanosoma cruzi, and T. brucei is mitogenic for B lymphocytes and stimulates macrophage expression of interleukin-12, tumor necrosis factor alpha, and nitric oxide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Induction of a Type 1 Immune Response following a Trypanosoma brucei Infection Is MyD88 Dependent
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endosomal translocation of vertebrate DNA activates dendritic cells via TLR9-dependent and -independent pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor-beta controls T helper type 1 cell development through regulation of natural killer cell interferon-gamma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Murine dendritic cells internalize Leishmania major promastigotes, produce IL-12 p40 and stimulate primary T cell proliferation in vitro.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Leishmania major-infected murine Langerhans cell-like dendritic cells from susceptible mice release IL-12 after infection and vaccinate against experimental cutaneous Leishmaniasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two waves of antigen-containing dendritic cells in vivo in experimental Leishmania major infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NK cell activation in visceral leishmaniasis requires TLR9, myeloid DCs, and IL-12, but is independent of plasmacytoid DCs.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered immune responses in mice lacking inducible nitric oxide synthase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Organ-specific and stage-dependent control of Leishmania major infection by inducible nitric oxide synthase and phagocyte NADPH oxidase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immune response in mice that lack the interferon-gamma receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Generation of nitric oxide and induction of major histocompatibility complex class II antigen in macrophages from mice lacking the interferon gamma receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nitric oxide biosynthesis, nitric oxide synthase inhibitors and arginase competition for L-arginine utilization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Translational control of inducible nitric oxide synthase by IL-13 and arginine availability in inflammatory macrophages.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TLR9-Dependent Recognition of MCMV by IPC and DC Generates Coordinated Cytokine Responses that Activate Antiviral NK Cell Function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-12 and the regulation of innate resistance and adaptive immunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Natural killer cells and dendritic cells: rendezvous in abused tissues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Close encounters of different kinds: dendritic cells and NK cells take centre stage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytokines induce the development of functionally heterogeneous T helper cell subsets
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression and function of Toll-like receptors in T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Arginase I induction during Leishmania major infection mediates the development of disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Arginase and polyamine synthesis are key factors in the regulation of experimental leishmaniasis in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice from a genetically resistant background lacking the interferon gamma receptor are susceptible to infection with Leishmania major but mount a polarized T helper cell 1-type CD4+ T cell response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CpG motif-independent activation of TLR9 upon endosomal translocation of "natural" phosphodiester DNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cutting edge: TLR9 and TLR2 signaling together account for MyD88-dependent control of parasitemia in Trypanosoma cruzi infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TLR9 is required for the gut-associated lymphoid tissue response following oral infection of Toxoplasma gondii
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fibroblasts as host cells in latent leishmaniosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunization of susceptible hosts with a soluble antigen fraction from Leishmania major leads to aggravation of murine leishmaniasis mediated by CD4+ T cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200737182
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1002/EJI.200737182
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18034422
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18034422%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
PubMed publication ID
18034422
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18034422
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18034422%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
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