(Q80051750)

English

PGC-1alpha Thr394Thr and Gly482Ser variants are significantly associated with T2DM in two North Indian populations: a replicate case-control study

scientific article published on 28 March 2007

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17390150%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

PGC-1alpha Thr394Thr and Gly482Ser variants are significantly associated with T2DM in two North Indian populations: a replicate case-control study (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17390150%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

4

1 reference

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28 December 2019

author name string

Audesh Bhat

1

1 reference

Europe PubMed Central

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28 December 2019

Anil Koul

2

1 reference

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28 December 2019

Ekta Rai

3

1 reference

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28 December 2019

M K Dhar

5

1 reference

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28 December 2019

R N K Bamezai

6

1 reference

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28 December 2019

publication date

28 March 2007

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28 December 2019

1 reference

Europe PubMed Central

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28 December 2019

121

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28 December 2019

609-614

1 reference

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28 December 2019

5

1 reference

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28 December 2019

https://scigraph.springernature.com/pub.10.1007/s00439-007-0352-0

0 references

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the peroxisome proliferator-activated receptor-gamma co-activator-1 Gly482Ser variant on features of the metabolic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor-gamma co-activator-1alpha (PGC-1alpha) gene polymorphisms and their relationship to Type 2 diabetes in Asian Indians

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of peroxisome proliferator-activated receptor-gamma coactivator-1alpha in the transcriptional regulation of the human uncoupling protein 2 gene in INS-1E cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Splicing mosaic of the myophosphorylase gene due to a silent mutation in McArdle disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

No association between the G482S polymorphism of the proliferator-activated receptor-gamma coactivator-1 (PGC-1) gene and Type II diabetes in French Caucasians

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired coactivator activity of the Gly482 variant of peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha) on mitochondrial transcription factor A (Tfam) promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global prevalence of diabetes: estimates for the year 2000 and projections for 2030

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial DNA G10398A polymorphism imparts maternal Haplogroup N a risk for breast and esophageal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation analysis of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial DNA polymorphism: its role in longevity of the Irish population

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor gamma coactivator-1alpha gene variations are not associated with gestational diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Meta-analysis of the Gly482Ser variant in PPARGC1A in type 2 diabetes and related phenotypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Gly482Ser missense mutation of the peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1 alpha) gene associates with reduced insulin sensitivity in normal and glucose-intolerant obese subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of beta cell energy metabolism and insulin release by PGC-1alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactive oxygen species have a causal role in multiple forms of insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRADalpha, and MO25alpha, in Peutz-Jeghers syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The coactivator PGC-1 is involved in the regulation of the liver carnitine palmitoyltransferase I gene expression by cAMP in combination with HNF4 alpha and cAMP-response element-binding protein (CREB)

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The possible role of 10398A and 16189C mtDNA variants in providing susceptibility to T2DM in two North Indian populations: a replicative study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17390150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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