(Q80080068)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16896919%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

title

Accumulation of A2-E in mitochondrial membranes of cultured RPE cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16896919%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

author name string

Florian Schutt

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16896919%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Marion Bergmann

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16896919%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Frank G Holz

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16896919%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Stefan Dithmar

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16896919%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Hans-Eberhard Volcker

5

1 reference

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28 December 2019

Jurgen Kopitz

6

1 reference

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28 December 2019

publication date

2 August 2006

1 reference

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Graefe's Archive for Clinical and Experimental Ophthalmology

28 December 2019

published in

1 reference

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28 December 2019

volume

245

1 reference

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28 December 2019

issue

3

1 reference

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28 December 2019

page(s)

391-398

1 reference

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https://scigraph.springernature.com/pub.10.1007/s00417-006-0376-5

28 December 2019

exact match

0 references

cites work

Isolation and characterization of a retinal pigment epithelial cell fluorophore: an all-trans-retinal dimer conjugate

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12 December 2020

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Interaction of A2E with model membranes. Implications to the pathogenesis of age-related macular degeneration.

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The biosynthesis of A2E, a fluorophore of aging retina, involves the formation of the precursor, A2-PE, in the photoreceptor outer segment membrane

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Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine.

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The pathophysiology of mitochondrial cell death

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12 December 2020

Isolation of intact lysosomes from human RPE cells and effects of A2-E on the integrity of the lysosomal and other cellular membranes

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Phosphatidylglycerol potently protects human retinal pigment epithelial cells against apoptosis induced by A2E, a compound suspected to cause age-related macula degeneration

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12 December 2020

The formation of autofluorescent granules in cultured human RPE

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12 December 2020

The epidemiology of age-related macular degeneration

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12 December 2020

Inhibition of the ATP-driven proton pump in RPE lysosomes by the major lipofuscin fluorophore A2-E may contribute to the pathogenesis of age-related macular degeneration

1 reference

12 December 2020

Photodamage to human RPE cells by A2-E, a retinoid component of lipofuscin

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Pathogenesis of lesions in late age-related macular disease

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12 December 2020

Isolation of subcellular organelles

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12 December 2020

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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12 December 2020

The identification of subcellular fractions from mammalian cells

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12 December 2020

DNA Is a Target of the Photodynamic Effects Elicited in A2E-Laden RPE by Blue-Light Illumination

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12 December 2020

A2E: a component of ocular lipofuscin

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12 December 2020

Biosynthetic studies of A2E, a major fluorophore of retinal pigment epithelial lipofuscin

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A role for vitamin A in the formation of ocular lipofuscin

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12 December 2020

Biosynthesis of a major lipofuscin fluorophore in mice and humans with ABCR-mediated retinal and macular degeneration

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12 December 2020

Lipids and lipid peroxidation products in the pathogenesis of age-related macular degeneration

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12 December 2020

Lipofuscin fluorophore inhibits lysosomal protein degradation and may cause early stages of macular degeneration

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12 December 2020

Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion

1 reference

12 December 2020

A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture.

1 reference

12 December 2020

1 reference

12 December 2020

Cytochrome c oxidase inhibition by N-retinyl-N-retinylidene ethanolamine, a compound suspected to cause age-related macula degeneration

1 reference

12 December 2020

Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium

1 reference

12 December 2020

RPE lipofuscin and its role in retinal pathobiology

1 reference

12 December 2020

Proteins modified by malondialdehyde, 4-hydroxynonenal, or advanced glycation end products in lipofuscin of human retinal pigment epithelium

1 reference

12 December 2020

Inhibition of lysosomal degradative functions in RPE cells by a retinoid component of lipofuscin

1 reference

12 December 2020

Lipofuscin and Macular Degeneration

1 reference

12 December 2020

A2E, a byproduct of the visual cycle

1 reference

12 December 2020