(Q80179101)

English

Role of thymidine phosphorylase and orotate phosphoribosyltransferase mRNA expression and its ratio to dihydropyrimidine dehydrogenase in the prognosis and clinicopathological features of patients with pancreatic cancer

scientific article published on 27 April 2007

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scholarly article

1 reference

Europe PubMed Central

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29 December 2019

Role of thymidine phosphorylase and orotate phosphoribosyltransferase mRNA expression and its ratio to dihydropyrimidine dehydrogenase in the prognosis and clinicopathological features of patients with pancreatic cancer (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17443278%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

pancreatic cancer

1 reference

based on heuristic

inferred from title

Tetsuya Ikemoto

4

1 reference

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29 December 2019

author name string

Kotaro Miyake

1

1 reference

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29 December 2019

Satoru Imura

2

1 reference

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29 December 2019

Tomoharu Yoshizumi

3

1 reference

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29 December 2019

Yuji Morine

5

1 reference

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29 December 2019

Mitsuo Shimada

6

1 reference

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29 December 2019

publication date

27 April 2007

1 reference

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29 December 2019

International Journal of Clinical Oncology

1 reference

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29 December 2019

12

1 reference

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29 December 2019

2

1 reference

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29 December 2019

111-119

1 reference

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29 December 2019

https://scigraph.springernature.com/pub.10.1007/s10147-006-0634-x

0 references

Angiogenesis in pancreatic carcinoma: thymidine phosphorylase expression in stromal cells and intratumoral microvessel density as independent predictors of overall and relapse-free survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and properties of an endothelial cell growth factor from human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both gene expression for orotate phosphoribosyltransferase and its ratio to dihydropyrimidine dehydrogenase influence outcome following fluoropyrimidine-based chemotherapy for metastatic colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Capecitabine: preclinical pharmacology studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thymidine phosphorylase and dihydropyrimidine dehydrogenase levels in primary colorectal cancer show a relationship to clinical effects of 5'-deoxy-5-fluorouridine as adjuvant chemotherapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical analysis of thymidylate synthase, p16(INK4a), cyclin-dependent kinase 4 and cyclin D1 in colorectal cancers receiving preoperative chemotherapy: significance of p16(INK4a)-mediated cellular arrest as an indicator of chemosensitiv

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dihydropyrimidine dehydrogenase and messenger RNA levels in gastric cancer: possible predictor for sensitivity to 5-fluorouracil.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical evaluation of thymidylate synthase (TS) and p16INK4a in advanced colorectal cancer: implication of TS expression in 5-FU-based adjuvant chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circumvention of 5-fluorouracil resistance in human stomach cancer cells by uracil phosphoribosyltransferase gene transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced activity of anabolizing enzymes in 5-fluorouracil-resistant human stomach cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of thymidine phosphorylase activity in the angiogenic effect of platelet derived endothelial cell growth factor/thymidine phosphorylase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thymidylate synthase and dihydropyrimidine dehydrogenase gene expression in relation to differentiation of gastric cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel method for real time quantitative RT-PCR.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition by oxonic acid of gastrointestinal toxicity of 5-fluorouracil without loss of its antitumor activity in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic significance of orotate phosphoribosyltransferase activity in bladder carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positive correlation between the efficacy of capecitabine and doxifluridine and the ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase activities in tumors in human cancer xenografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiogenic activity of enzymes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

UFT: mechanism of drug action.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dihydropyrimidine dehydrogenase activity and fluorouracil chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical relevance of the concentrations of both pyrimidine nucleoside phosphorylase (PyNPase) and dihydropyrimidine dehydrogenase (DPD) in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression for dihydropyrimidine dehydrogenase and thymidine phosphorylase influences outcome in epithelial ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thymidine phosphorylase activity associated with platelet-derived endothelial cell growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Response to fluorouracil therapy in cancer patients: the role of tumoral dihydropyrimidine dehydrogenase activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzymatic cleavage of various fluorinated pyrimidine nucleosides to 5-fluorouracil and their antiproliferative activities in human and murine tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluorouracil: biochemistry and pharmacology

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dihydropyrimidine dehydrogenase but not thymidylate synthase expression is associated with resistance to 5-fluorouracil in colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression levels of thymidine phosphorylase and dihydropyrimidine dehydrogenase in various human tumor tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenovirus-mediated transduction of Escherichia coli uracil phosphoribosyltransferase gene sensitizes cancer cells to low concentrations of 5-fluorouracil

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinicopathological and prognostic significance of thymidine phosphorylase and proliferating cell nuclear antigen in gastric carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of thymidine phosphorylase and dihydropyrimidine dehydrogenase in tumour progression and sensitivity to doxifluridine in gastric cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17443278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S10147-006-0634-X

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17443278%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17443278%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

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