(Q80237617)

English

Neutrophil elastase inhibitor (sivelestat) preserves antitumor immunity and reduces the inflammatory mediators associated with major surgery

scientific article published on 30 April 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17468814%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Neutrophil elastase inhibitor (sivelestat) preserves antitumor immunity and reduces the inflammatory mediators associated with major surgery (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17468814%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

author name string

Shintaro Akamoto

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17468814%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Keiichi Okano

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17468814%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Takanori Sano

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17468814%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Shinichi Yachida

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17468814%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Kunihiko Izuishi

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17468814%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Hisashi Usuki

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17468814%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Hisao Wakabayashi

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17468814%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Yasuyuki Suzuki

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17468814%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

publication date

30 April 2007

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17468814%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17468814%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

37

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17468814%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17468814%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

359-365

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17468814%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Major surgery suppresses maximal production of helper T-cell type 1 cytokines without potentiating the release of helper T-cell type 2 cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of an immunosuppressive acidic protein from ascitic fluids of cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of preoperative steroid administration on surgical stress in hepatic resection: prospective randomized trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of laparotomy and laparoscopy on the establishment of spontaneous tumor metastases

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical benefits of steroid therapy on surgical stress in patients with esophageal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Randomized study of the benefits of preoperative corticosteroid administration on the postoperative morbidity and cytokine response in patients undergoing surgery for esophageal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Augmented enhancement of in vitro production of inflammatory cytokines in peripheral blood mononuclear cells in patients undergoing simultaneous resection of the liver and gastrointestinal tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutrophil elastase inhibition in acute lung injury: results of the STRIVE study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunosuppressive acidic protein (IAP) level in serum and peritoneal washings, and its implication in determining multidisciplinary treatments

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukocyte surface origin of human alpha1-acid glycoprotein (orosomucoid).

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of a perioperative steroid pulse on surgical stress in hepatic resection

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of granulocyte colony-stimulating factor (G-CSF) and neutrophil elastase inhibitor (ONO-5046) on acid-induced lung injury in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sivelestat, a specific neutrophil elastase inhibitor, suppresses the growth of gastric carcinoma cells by preventing the release of transforming growth factor-alpha.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between neutrophil elastase and acute lung injury in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of perioperative protease inhibitor on inflammatory cytokines and acute-phase proteins in patients with hepatic resection

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of a human protease inhibitor on surgical stress induced immunosuppression

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Surgical stress induces a shift in the type-1/type-2 T-helper cell balance, suggesting down-regulation of cell-mediated and up-regulation of antibody-mediated immunity commensurate to the trauma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum Immunosuppressive Acidic Protein as an Interleukin-6 Related Index of Deteriorating Condition in Gastric Cancer Patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of a protease inhibitor on reduction of surgical stress in esophagectomy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T lymphocyte subsets and Th1/Th2 balance after laparoscopy-assisted distal gastrectomy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutrophil elastase inhibitor (ONO-5046.Na) decreases production of proinflammatory cytokines by lipopolysaccharide-stimulated human monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sivelestat reduces inflammatory mediators and preserves neutrophil deformability during simulated extracorporeal circulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Th2 subset dominance among peripheral blood T lymphocytes in patients with digestive cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutrophil elastase inhibitor (ONO-5046) decreases cytokine-induced neutrophil chemoattractant after reperfusion of pancreaticoduodenal transplantation in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of combined prednisolone, epidural analgesia, and indomethacin on the systemic response after colonic surgery.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced hepatic acute-phase response after simultaneous resection for gastrointestinal cancer with synchronous liver metastases

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum interleukin-6 level reflects the tumor proliferative activity in patients with colorectal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo analysis of the suppressive effects of immunosuppressive acidic protein, a type of alpha 1-acid glycoprotein, in connection with its high level in tumor-bearing mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17468814

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00595-006-3409-0

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17468814%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17468814%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

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