(Q80363792)

English

Efficacy and Safety of the Platelet-Activating Factor Receptor Antagonist BN 52021 (Ginkgolide B) in Patients with Severe Sepsis : A Randomised, Double-Blind, Placebo-Controlled, Multicentre Trial

scientific article published on 01 January 2004

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Efficacy and Safety of the Platelet-Activating Factor Receptor Antagonist BN 52021 (Ginkgolide B) in Patients with Severe Sepsis : A Randomised, Double-Blind, Placebo-Controlled, Multicentre Trial (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

based on heuristic

inferred from title

multicenter clinical trial

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

D M Albrecht

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

K van Ackern

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

H-J Bender

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

H Hof

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

W Kox

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

N Victor

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

P Funk

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

M Kieser

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

S Köhler

9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

D Krausch

10

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

I Marzi

11

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

T Menges

12

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

H Schmidt

13

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

publication date

1 January 2004

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Clinical Drug Investigation

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

24

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

137-147

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Intensive Care Society's APACHE II study in Britain and Ireland--I: Variations in case mix of adult admissions to general intensive care units and impact on outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet-activating factor (PAF) receptor and genetically engineered PAF receptor mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treating patients with severe sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravascular release of platelet activating factor in children with sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Multiple Testing Procedure for Clinical Trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An expanded definition of the adult respiratory distress syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma degradation of platelet-activating factor in severely ill patients with clinical sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Occupancy of platelet receptors for platelet-activating factor in patients with septicemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet activating factor receptor antagonist improves survival and attenuates eicosanoid release in severe endotoxemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The prevalence of nosocomial infection in intensive care units in Europe. Results of the European Prevalence of Infection in Intensive Care (EPIC) Study. EPIC International Advisory Committee

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Perspectives in platelet-activating factor research

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

4G/5G promoter polymorphism in the plasminogen-activator-inhibitor-1 gene and outcome of meningococcal disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions between platelet activating factor and eicosanoids during endotoxic shock in anaesthetized pigs

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prospective study of aetiology and outcome of adult lower-respiratory-tract infections in the community

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A PAF receptor antagonist, BN 52021, attenuates thromboxane release and improves survival in lethal canine endotoxemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of TNF2, a TNF-alpha promoter polymorphism, with septic shock susceptibility and mortality: a multicenter study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet-activating factor receptor antagonist BN 52021 in the treatment of severe sepsis: a randomized, double-blind, placebo-controlled, multicenter clinical trial. BN 52021 Sepsis Study Group.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased organ failure in patients with severe SIRS and septic shock treated with the platelet-activating factor antagonist TCV-309: a prospective, multicenter, double-blind, randomized phase II trial. TCV-309 Septic Shock Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of PAF-acether and blood volume changes in gram-negative sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Test statistics and sample size formulae for comparative binomial trials with null hypothesis of non-zero risk difference or non-unity relative risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Outcomes research exemplified by infection]

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet activating factor and its role in trauma, shock, and sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet activating factor is one of the mediators involved in endotoxic shock in pigs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic options directed against platelet activating factor, eicosanoids and bradykinin in sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment with the platelet-activating factor antagonist TCV-309 in patients with severe systemic inflammatory response syndrome: a prospective, multi-center, double-blind, randomized phase II trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variation in plasminogen-activator-inhibitor-1 gene and risk of meningococcal septic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Confirmatory platelet-activating factor receptor antagonist trial in patients with severe gram-negative bacterial sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial. BN 52021 Sepsis Investigator Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simplified acute physiology score for ICU patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

APACHE II: a severity of disease classification system

1 reference

https://pubmed.ncbi.nlm.nih.gov/17516700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2165/00044011-200424030-00002

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17516700%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

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