(Q80373594)

English

DNA vaccination encoding glutamic acid decarboxylase can enhance insulitis and diabetes in correlation with a specific Th2/3 CD4 T cell response in non-obese diabetic mice

scientific article published on 01 August 2004

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15270841%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

DNA vaccination encoding glutamic acid decarboxylase can enhance insulitis and diabetes in correlation with a specific Th2/3 CD4 T cell response in non-obese diabetic mice (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15270841%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

based on heuristic

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author name string

A Gauvrit

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15270841%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

M Debailleul

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15270841%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

A-T Vu

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15270841%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

P Sai

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15270841%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

J-M Bach

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15270841%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

publication date

1 August 2004

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15270841%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Clinical and Experimental Immunology

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15270841%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

137

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15270841%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15270841%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

253-262

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15270841%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

T helper 2 (Th2) T cells induce acute pancreatitis and diabetes in immune-compromised nonobese diabetic (NOD) mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of antiviral antibodies by DNA immunization requires neither perforin-mediated nor CD8(+)-T-cell-mediated lysis of antigen-expressing cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene vaccination: plasmid DNA is more than just a blueprint

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of GAD65-specific regulatory T-cells inhibits ongoing autoimmune diabetes in nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The need for IgG2c specific antiserum when isotyping antibodies from C57BL/6 and NOD mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abrogation of autoimmune diabetes in nonobese diabetic mice and protection against effector lymphocytes by transgenic paracrine TGF-beta1

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TGF-beta1 somatic gene therapy prevents autoimmune disease in nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA vaccination with glutamic acid decarboxylase (GAD) generates a strong humoral immune response in BALB/c, C57BL/6, and in diabetes-prone NOD mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presence or absence of TGF-beta determines IL-4-induced generation of type 1 or type 2 CD8 T cell subsets

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of autoimmune diabetes in NOD mice by GAD expression or suppression in beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA immunization to prevent autoimmune diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pancreatic IL-4 expression results in islet-reactive Th2 cells that inhibit diabetogenic lymphocytes in the nonobese diabetic mouse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA vaccines: immunology, application, and optimization*

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vaccination with empty plasmid DNA or CpG oligonucleotide inhibits diabetes in nonobese diabetic mice: modulation of spontaneous 60-kDa heat shock protein autoimmunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antigen-specific mediated suppression of beta cell autoimmunity by plasmid DNA vaccination

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vaccination with glutamic acid decarboxylase plasmid DNA protects mice from spontaneous autoimmune diabetes and B7/CD28 costimulation circumvents that protection

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasmid DNAs encoding insulin and glutamic acid decarboxylase 65 have distinct effects on the progression of autoimmune diabetes in nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunization with DNA encoding an immunodominant peptide of insulin prevents diabetes in NOD mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasmid vaccination with insulin B chain prevents autoimmune diabetes in nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endogenous expression levels of autoantigens influence success or failure of DNA immunizations to prevent type 1 diabetes: addition of IL-4 increases safety

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CpG motifs in bacterial DNA and their immune effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pancreatic lymph nodes are required for priming of beta cell reactive T cells in NOD mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of autoimmune diabetes through insulin (but not GAD65) DNA vaccination in nonobese diabetic and in RIP-B7.1 mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both the Lyt-2+ and L3T4+ T cell subsets are required for the transfer of diabetes in nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cell-mediated inhibition of the transfer of autoimmune diabetes in NOD mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin immunization of nonobese diabetic mice induces a protective insulitis characterized by diminished intraislet interferon-gamma transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T helper cell subsets in insulin-dependent diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of organ cultured fetal pancreas allo-, iso-, and xenografts (pig) in non-immunosuppressed non-obese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological enhancement of in vivo foreign gene expression in muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunization of non-obese diabetic (NOD) mice with glutamic acid decarboxylase-derived peptide 524-543 reduces cyclophosphamide-accelerated diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetogenic T-cell clones

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myelin basic protein-specific T helper 2 (Th2) cells cause experimental autoimmune encephalomyelitis in immunodeficient hosts rather than protect them from the disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15270841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2249.2004.02546.X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15270841%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15270841%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

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