(Q80448479)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17557109%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

title

Intratumoral injection of IL-12 plasmid DNA--results of a phase I/IB clinical trial (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17557109%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

main subject

phase I clinical trial

1 reference

Mahvi DM

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17557109%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Henry MB

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17557109%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Albertini MR

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17557109%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Weber S

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17557109%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Meredith K

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17557109%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Schalch H

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17557109%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Rakhmilevich A

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17557109%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Hank J

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17557109%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Sondel P

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17557109%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

publication date

8 June 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17557109%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17557109%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

volume

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17557109%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17557109%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

page(s)

717-723

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17557109%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.cgt.7701064

31 December 2019

exact match

0 references

cites work

Cancer immunotherapy by direct in vivo transfer of immunomodulatory genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Cytokine gene therapy of cancer using gene gun technology: superior antitumor activity of interleukin-12.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Antitumor efficacy of adenocarcinoma cells engineered to produce interleukin 12 (IL-12) or other cytokines compared with exogenous IL-12.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Gene therapy with a single chain interleukin 12 fusion protein induces T cell-dependent protective immunity in a syngeneic model of murine neuroblastoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Role of NK and T cells in IL-12-induced anti-tumor response against hepatic colon carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Perforin-dependent NK cell cytotoxicity is sufficient for anti-metastatic effect of IL-12

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Interleukin-12 gene therapy of a weakly immunogenic mouse mammary carcinoma results in reduction of spontaneous lung metastases via a T-cell-independent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Interleukin 12 induces stable priming for interferon gamma (IFN-gamma) production during differentiation of human T helper (Th) cells and transient IFN-gamma production in established Th2 cell clones

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Administration of recombinant IL-12 to normal mice enhances cytolytic lymphocyte activity and induces production of IFN-gamma in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Inhibition of angiogenesis in vivo by interleukin 12.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Gene gun-mediated skin transfection with interleukin 12 gene results in regression of established primary and metastatic murine tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Murine models of cancer cytokine gene therapy using interleukin-12.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

1 reference

7 January 2021

The toxicology of interleukin-12: a review

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Neural toxicity of retroviruses.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Direct Intratumoral Injection of an Adenovirus Expressing Interleukin-12 Induces Regression and Long-Lasting Immunity That Is Associated with Highly Localized Expression of Interleukin-12

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Intratumoral coinjection of adenoviral vectors expressing IL-2 and IL-12 results in enhanced frequency of regression of injected and untreated distal tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Virus treatment questioned after gene therapy death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Interleukin-12 gene transfer results in CD8-dependent regression of murine CT26 liver tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Synergistic inhibition of tumor growth in a murine mammary adenocarcinoma model by combinational gene therapy using IL-12, pro-IL-18, and IL-1beta converting enzyme cDNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Introduction of murine Il-4 gene into B16(F10) melanoma tumors by direct gene transfer with DNA-liposome complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Tissue distribution of the cytofectin component of a plasmid-DNA/cationic lipid complex following intravenous administration in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

A new cationic liposome DNA complex enhances the efficiency of arterial gene transfer in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Intratracheal administration of interleukin 12 plasmid-cationic lipid complexes inhibits murine lung metastases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

A gene therapy for cancer using intramuscular injection of plasmid DNA encoding interferon alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Intratumoral delivery of IL-12 gene by polyvinyl polymeric vector system to murine renal and colon carcinoma results in potent antitumor immunity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Particle-mediated gene transfer of granulocyte-macrophage colony-stimulating factor cDNA to tumor cells: implications for a clinically relevant tumor vaccine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Long-lasting anti-metastatic efficiency of interleukin 12-encoding plasmid DNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Antimetastatic vaccination against Lewis lung carcinoma with autologous tumor cells modified to express murine interleukin 12

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Accumulation of IL-12-activated antitumor effector cells into lymph nodes of tumor-bearing mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Safety of interleukin-12 gene therapy against cancer: a murine biodistribution and toxicity study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

IL-12 + GM-CSF microsphere therapy induces eradication of advanced spontaneous tumors in her-2/neu transgenic mice but fails to achieve long-term cure due to the inability to maintain effector T-cell activity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701064

7 January 2021

Identifiers

DOI

10.1038/SJ.CGT.7701064

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17557109%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference