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Keratin 8 and 18 hyperphosphorylation is a marker of progression of human liver disease
scientific article published on 01 August 2004
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scholarly article
1 reference
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Europe PubMed Central
PubMed publication ID
15368451
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15368451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
title
Keratin 8 and 18 hyperphosphorylation is a marker of progression of human liver disease
(English)
1 reference
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Europe PubMed Central
PubMed publication ID
15368451
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15368451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
main subject
liver disease
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author
Bishr Omary
series ordinal
6
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Europe PubMed Central
PubMed publication ID
15368451
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15368451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
author name string
Diana M Toivola
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
15368451
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15368451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
Nam-On Ku
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2
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Europe PubMed Central
PubMed publication ID
15368451
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15368451%20AND%20SRC:MED&resulttype=core&format=json
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1 January 2020
Evelyn Z Resurreccion
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3
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Europe PubMed Central
PubMed publication ID
15368451
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15368451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
David R Nelson
series ordinal
4
1 reference
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Europe PubMed Central
PubMed publication ID
15368451
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15368451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
Teresa L Wright
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15368451
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15368451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
language of work or name
English
0 references
publication date
1 August 2004
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15368451
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15368451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
published in
Hepatology
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Europe PubMed Central
PubMed publication ID
15368451
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15368451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
volume
40
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Europe PubMed Central
PubMed publication ID
15368451
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15368451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
issue
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15368451
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15368451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
page(s)
459-466
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15368451
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15368451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
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Keratin 8 mutations in patients with cryptogenic liver disease
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7 January 2021
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Keratin 8 and 18 mutations are risk factors for developing liver disease of multiple etiologies.
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Phosphorylation of human keratin 18 serine 33 regulates binding to 14-3-3 proteins
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Keratin binding to 14-3-3 proteins modulates keratin filaments and hepatocyte mitotic progression
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7 January 2021
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Keratin 8 phosphorylation by p38 kinase regulates cellular keratin filament reorganization: modulation by a keratin 1-like disease causing mutation
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Crossref
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Keratins turn over by ubiquitination in a phosphorylation-modulated fashion
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Effect of mutation and phosphorylation of type I keratins on their caspase-mediated degradation.
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Mutation of a major keratin phosphorylation site predisposes to hepatotoxic injury in transgenic mice
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Keratin-8 null mice have different gallbladder and liver susceptibility to lithogenic diet-induced injury
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Type II keratins are phosphorylated on a unique motif during stress and mitosis in tissues and cultured cells.
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Hepatocyte cytokeratins are hyperphosphorylated at multiple sites in human alcoholic hepatitis and in a mallory body mouse model
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Cytokeratin 8 protects from hepatotoxicity, and its ratio to cytokeratin 18 determines the ability of hepatocytes to form Mallory bodies
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Mallory body formation in primary biliary cirrhosis is associated with increased amounts and abnormal phosphorylation and ubiquitination of cytokeratins
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Interleukin 10 treatment reduces fibrosis in patients with chronic hepatitis C: a pilot trial of interferon nonresponders
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Chronic hepatitis, hepatocyte fragility, and increased soluble phosphoglycokeratins in transgenic mice expressing a keratin 18 conserved arginine mutant
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Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis
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Stress, apoptosis, and mitosis induce phosphorylation of human keratin 8 at Ser-73 in tissues and cultured cells
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Phosphorylation of human keratin 8 in vivo at conserved head domain serine 23 and at epidermal growth factor-stimulated tail domain serine 431
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Simple epithelial keratins are dispensable for cytoprotection in two pancreatitis models
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Dynamics of human keratin 18 phosphorylation: polarized distribution of phosphorylated keratins in simple epithelial tissues
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The intermediate filament protein keratin 8 is a novel cytoplasmic substrate for c-Jun N-terminal kinase.
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Keratin mutation in transgenic mice predisposes to Fas but not TNF-induced apoptosis and massive liver injury.
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Hyperphosphorylation and accumulation of neurofilament proteins in Alzheimer disease brain and in okadaic acid-treated SY5Y cells
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Desmin phosphorylation abnormalities in cytoplasmic body and desmin-related myopathies
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Phosphorylation of cytokeratin 8 and 18 in human vascular smooth muscle cells of atherosclerotic lesions and umbilical cord vessels
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Unique phosphorylation of vimentin filaments in glomerular epithelial cells in culture and in disease
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Hepatocyte apoptosis is a pathologic feature of human alcoholic hepatitis
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inferred from DOI database lookup
Apoptosis and liver disease
1 reference
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Crossref
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https://api.crossref.org/works/10.1002%2FHEP.20277
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Apoptosis generates stable fragments of human type I keratins
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7 January 2021
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A specific ELISA for measuring neurofilament heavy chain phosphoforms
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7 January 2021
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Identification of the major physiologic phosphorylation site of human keratin 18: potential kinases and a role in filament reorganization
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1002/HEP.20277
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15368451
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15368451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
PubMed publication ID
15368451
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15368451
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15368451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
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