(Q80580563)

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Depletion of CD25+ cells from human T-cell enriched fraction eliminates immunodominance during priming with dendritic cells genetically modified to express a secreted protein

scientific article published on 01 February 2005

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1 January 2020

Depletion of CD25+ cells from human T-cell enriched fraction eliminates immunodominance during priming with dendritic cells genetically modified to express a secreted protein (English)

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1 January 2020

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Yevhen Makohonenko

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Milcho Mincheff

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1 January 2020

Serguei Zoubak

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Iskra Altankova

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1 January 2020

Stoyan Tchakarov

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Petro Pogribnyy

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Chavdar Botev

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Harold T Meryman

8

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publication date

1 February 2005

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1 January 2020

Cancer Gene Therapy

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185-197

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1 January 2020

2

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1 January 2020

https://scigraph.springernature.com/pub.10.1038/sj.cgt.7700778

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Human cd25(+)cd4(+) t regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function.

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CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

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Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance

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Homozygous deletions that simultaneously eliminate expressions of class I and class II antigens of EBV-transformed B-lymphoblastoid cells. I. Reduced proliferative responses of autologous and allogeneic T cells to mutant cells that have decreased ex

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Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

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Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

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Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood

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Identifiers

10.1038/SJ.CGT.7700778

1 reference

Europe PubMed Central

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1 reference

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