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Translocator protein 18 kDa is involved in the regulation of reactive gliosis
scientific article published on 01 November 2007
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Europe PubMed Central
PubMed publication ID
17674368
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17674368%20AND%20SRC:MED&resulttype=core&format=json
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3 January 2020
title
Translocator protein 18 kDa is involved in the regulation of reactive gliosis
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17674368
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17674368%20AND%20SRC:MED&resulttype=core&format=json
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3 January 2020
author
Iñigo Azcoitia
series ordinal
4
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Europe PubMed Central
PubMed publication ID
17674368
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17674368%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
Luis Miguel Garcia-Segura
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5
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Europe PubMed Central
PubMed publication ID
17674368
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3 January 2020
author name string
Sergio Veiga
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1
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Europe PubMed Central
PubMed publication ID
17674368
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17674368%20AND%20SRC:MED&resulttype=core&format=json
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3 January 2020
Paloma Carrero
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2
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Europe PubMed Central
PubMed publication ID
17674368
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17674368%20AND%20SRC:MED&resulttype=core&format=json
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3 January 2020
Olga Pernia
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3
1 reference
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Europe PubMed Central
PubMed publication ID
17674368
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17674368%20AND%20SRC:MED&resulttype=core&format=json
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3 January 2020
publication date
1 November 2007
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17674368
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17674368%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
published in
Glia
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17674368
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17674368%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
volume
55
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Europe PubMed Central
PubMed publication ID
17674368
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17674368%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
issue
14
1 reference
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Europe PubMed Central
PubMed publication ID
17674368
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17674368%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
page(s)
1426-1436
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17674368
reference URL
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3 January 2020
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Binding of [3H]Ro 5-4864 and [3H]PK 11195 to cerebral cortex and peripheral tissues of various species: species differences and heterogeneity in peripheral benzodiazepine binding sites
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High-affinity peripheral benzodiazepine receptor ligand, PK11195, regulates protein phosphorylation in rat brain mitochondria under control of Ca(2+).
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PK ('peripheral benzodiazepine')--binding sites in the CNS indicate early and discrete brain lesions: microautoradiographic detection of [3H]PK11195 binding to activated microglia
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Evaluation of three quinoline-carboxamide derivatives as potential radioligands for the in vivo pet imaging of neurodegeneration.
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Immunomodulatory effect of peripheral benzodiazepine receptor ligands on human mononuclear cells
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Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
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Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H)diazepam binding
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Ligands of the peripheral benzodiazepine receptor have therapeutic effects in pneumopathies in vivo
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Neurodegeneration in the rat hippocampus and striatum after middle cerebral artery occlusion.
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In vivo visualization of activated glia by [11C] (R)-PK11195-PET following herpes encephalitis reveals projected neuronal damage beyond the primary focal lesion.
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Glial reaction to volkensin-induced selective degeneration of central neurons.
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Peripheral benzodiazepine receptor ligands: mitochondrial transmembrane potential depolarization and apoptosis induction in rat C6 glioma cells
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Peripheral benzodiazepine receptor imaging in CNS demyelination: functional implications of anatomical and cellular localization
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7 January 2021
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Inhibition of lipopolysaccharide-induced cyclooxygenase-2, tumor necrosis factor-alpha and [Ca2+]i responses in human microglia by the peripheral benzodiazepine receptor ligand PK11195.
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7 January 2021
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Assessment and prognostic significance of mitotic index using the mitosis marker phospho-histone H3 in low and intermediate-grade infiltrating astrocytomas.
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7 January 2021
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Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases
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7 January 2021
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Fluoro-Jade B staining as useful tool to identify activated microglia and astrocytes in a mouse transgenic model of Alzheimer's disease
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7 January 2021
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inferred from DOI database lookup
Role of activated astrocytes in neuronal damage: potential links to HIV-1-associated dementia
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Crossref
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https://api.crossref.org/works/10.1002%2FGLIA.20558
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7 January 2021
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inferred from DOI database lookup
Estrogen and brain inflammation: effects on microglial expression of MHC, costimulatory molecules and cytokines.
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7 January 2021
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inferred from DOI database lookup
Molecular profile of reactive astrocytes--implications for their role in neurologic disease
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7 January 2021
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inferred from DOI database lookup
Involvement of steroids in anti-inflammatory effects of peripheral benzodiazepine receptor ligands
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7 January 2021
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Reactive astrocytes protect tissue and preserve function after spinal cord injury
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7 January 2021
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The peripheral benzodiazepine receptor: a promising therapeutic drug target
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7 January 2021
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Glia-neuron crosstalk in the neuroprotective mechanisms of sex steroid hormones
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7 January 2021
based on heuristic
inferred from DOI database lookup
Steroids and glial cell function.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
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7 January 2021
based on heuristic
inferred from DOI database lookup
PK11195 potently sensitizes to apoptosis induction independently from the peripheral benzodiazepin receptor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
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7 January 2021
based on heuristic
inferred from DOI database lookup
Microglia as a source and target of cytokines
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
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7 January 2021
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inferred from DOI database lookup
Peripheral benzodiazepine receptor (PBR) ligand cytotoxicity unrelated to PBR expression
1 reference
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Crossref
reference URL
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inferred from DOI database lookup
Brain inflammatory response induced by intracerebroventricular infusion of lipopolysaccharide: an immunohistochemical study
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial ligand inhibits store-operated calcium influx and COX-2 production in human microglia.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitory action of 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxam ide (PK 11195) on some mononuclear phagocyte functions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular and subcellular localization of peripheral benzodiazepine receptors after trimethyltin neurotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
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7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of peripheral benzodiazepine receptor in the oxidative stress, death-signaling pathways, and renal injury induced by ischemia-reperfusion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peripheral-type benzodiazepine receptor: structure and function of a cholesterol-binding protein in steroid and bile acid biosynthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microglial cell population dynamics in the injured adult central nervous system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differentiation between two ligands for peripheral benzodiazepine binding sites, [3H]R05-4864 and [3H]PK 11195, by thermodynamic studies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peripheral benzodiazepine receptor ligand, PK11195 induces mitochondria cytochrome c release and dissipation of mitochondria potential via induction of mitochondria permeability transition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peripheral-type benzodiazepine receptor overexpression and knockdown in human breast cancer cells indicate its prominent role in tumor cell proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
To be or not to be (inflamed)--is that the question in anti-inflammatory drug therapy of neurodegenerative disorders?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of peripheral benzodiazepine receptors on the function and survival of isolated human pancreatic islets
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Benzodiazepines and peptides stimulate pregnenolone synthesis in brain mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial benzodiazepine receptors regulate steroid biosynthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of major histocompatibility class II antigen on microglial cells in postnatal and adult rats following intraperitoneal injections of lipopolysaccharide.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peripheral benzodiazepine receptor in cholesterol transport and steroidogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Topography of the Leydig cell mitochondrial peripheral-type benzodiazepine receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Up-regulation of PK11195 binding in areas of axonal degeneration coincides with early microglial activation in mouse brain.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Astrocyte activation and reactive gliosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular inflammatory response after spinal cord injury in Sprague-Dawley and Lewis rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reactive astrocytes: cellular and molecular cues to biological function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effect of activated microglia on astrogliosis parameters in astrocyte cultures.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peripheral benzodiazepine receptor ligand PK11195 reduces microglial activation and neuronal death in quinolinic acid-injected rat striatum
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Astrocytes enhance lipopolysaccharide-induced nitric oxide production by microglial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peripheral benzodiazepine receptors are colocalized with activated microglia following transient global forebrain ischemia in the rat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Indicators of glial activation and brain oxidative stress after intraventricular infusion of endotoxin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Roles of glia-derived cytokines on neuronal degeneration and regeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two mitosis-specific antibodies, MPM-2 and phospho-histone H3 (Ser28), allow rapid and precise determination of mitotic activity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anti-inflammatory effects of peripheral benzodiazepine receptor ligands in two mouse models of inflammation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peripheral-type benzodiazepine receptor density and in vitro tumorigenicity of glioma cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Estrogen receptor-alpha mediates the brain antiinflammatory activity of estradiol
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ro5-4864, a peripheral benzodiazepine receptor ligand, reduces reactive gliosis and protects hippocampal hilar neurons from kainic acid excitotoxicity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The peripheral benzodiazepine receptor (Translocator protein 18kDa) in microglia: from pathology to imaging
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PK11195, a peripheral benzodiazepine receptor (pBR) ligand, broadly blocks drug efflux to chemosensitize leukemia and myeloma cells by a pBR-independent, direct transporter-modulating mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The peripheral benzodiazepine receptor ligand PK 11195 inhibits arthritis in the MRL-lpr mouse model
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of benzodiazepine receptors in neuroinflammatory and neurodegenerative diseases: evidence from activated microglial cells in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FGLIA.20558
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1002/GLIA.20558
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17674368
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17674368%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
PubMed publication ID
17674368
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17674368
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17674368%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
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