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PPARdelta is a type 1 IFN target gene and inhibits apoptosis in T cells
scientific article published on 28 February 2008
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Europe PubMed Central
PubMed publication ID
18305567
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18305567%20AND%20SRC:MED&resulttype=core&format=json
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3 January 2020
title
PPARdelta is a type 1 IFN target gene and inhibits apoptosis in T cells
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18305567
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18305567%20AND%20SRC:MED&resulttype=core&format=json
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3 January 2020
author name string
Nadya al Yacoub
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1
1 reference
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Europe PubMed Central
PubMed publication ID
18305567
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18305567%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
Malgorzata Romanowska
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2
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Europe PubMed Central
PubMed publication ID
18305567
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18305567%20AND%20SRC:MED&resulttype=core&format=json
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3 January 2020
Sybille Krauss
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3
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Europe PubMed Central
PubMed publication ID
18305567
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18305567%20AND%20SRC:MED&resulttype=core&format=json
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3 January 2020
Susann Schweiger
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4
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PubMed publication ID
18305567
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3 January 2020
John Foerster
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5
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Europe PubMed Central
PubMed publication ID
18305567
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18305567%20AND%20SRC:MED&resulttype=core&format=json
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3 January 2020
language of work or name
English
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publication date
28 February 2008
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18305567
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18305567%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
published in
Journal of Investigative Dermatology
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Europe PubMed Central
PubMed publication ID
18305567
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18305567%20AND%20SRC:MED&resulttype=core&format=json
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3 January 2020
volume
128
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Europe PubMed Central
PubMed publication ID
18305567
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18305567%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
issue
8
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Europe PubMed Central
PubMed publication ID
18305567
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18305567%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
page(s)
1940-1949
1 reference
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Europe PubMed Central
PubMed publication ID
18305567
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18305567%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
exact match
https://scigraph.springernature.com/pub.10.1038/jid.2008.32
0 references
cites work
PPAR delta: a dagger in the heart of the metabolic syndrome
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Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-alpha
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Ligand activation of peroxisome proliferator-activated receptor-beta/delta(PPARbeta/delta) inhibits cell growth of human N/TERT-1 keratinocytes
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7 January 2021
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The role of peroxisome proliferator-activated receptor-beta/delta in epithelial cell growth and differentiation
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Evolution of peroxisome proliferator-activated receptor agonists
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Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation
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The Cyclopentenone-Type Prostaglandin 15-Deoxy-Δ12,14-Prostaglandin J2 Inhibits CD95 Ligand Gene Expression in T Lymphocytes: Interference with Promoter Activation Via Peroxisome Proliferator-Activated Receptor-γ-Independent Mechanisms
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Transcriptional repression of peroxisome proliferator-activated receptor beta/delta in murine keratinocytes by CCAAT/enhancer-binding proteins
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The anti-apoptotic role of PPARβ contributes to efficient skin wound healing
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Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway.
1 reference
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The human peroxisome proliferator-activated receptor delta gene is a primary target of 1alpha,25-dihydroxyvitamin D3 and its nuclear receptor
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Peroxisome proliferator-activated receptor (PPAR)alpha expression in T cells mediates gender differences in development of T cell-mediated autoimmunity
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Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression
1 reference
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Evidence that apoptosis and terminal differentiation of epidermal keratinocytes are distinct processes
1 reference
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The nuclear receptor PPAR gamma is expressed by mouse T lymphocytes and PPAR gamma agonists induce apoptosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2008.32
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Induction of apoptosis in mouse T cells upon peroxisome proliferator-activated receptor gamma (PPAR-gamma) binding
1 reference
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Crossref
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PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs
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Molecular mechanisms of activated T cell death in vivo
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Oxidative stress employs phosphatidyl inositol 3-kinase and ERK signalling pathways to activate cAMP phosphodiesterase-4D3 (PDE4D3) through multi-site phosphorylation at Ser239 and Ser579.
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Expression of activated MEK1 in differentiating epidermal cells is sufficient to generate hyperproliferative and inflammatory skin lesions
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Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma
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Functions of the peroxisome proliferator-activated receptor (PPAR) alpha and beta in skin homeostasis, epithelial repair, and morphogenesis
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Peroxisome proliferator-activated receptor alpha, delta, gamma1 and gamma2 expressions are present in human monocyte-derived dendritic cells and modulate dendritic cell maturation by addition of subtype-specific ligands
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Nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha) is expressed in resting murine lymphocytes. The PPARalpha in T and B lymphocytes is both transactivation and transrepression competent
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Peroxisome proliferator-activated receptor alpha negatively regulates T-bet transcription through suppression of p38 mitogen-activated protein kinase activation
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15-Deoxy-delta12,14-PGJ2 inhibits IL-6-induced Stat3 phosphorylation in lymphocytes
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Soluble form of heparin-binding EGF-like growth factor contributes to retinoic acid-induced epidermal hyperplasia
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Correlation of psoriasis activity with abundance of CD25+CD8+ T cells: conditions for cloning T cells from psoriatic plaques
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PPARs in diseases: control mechanisms of inflammation
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Effect of topical PPARbeta/delta and PPARgamma agonists on plaque psoriasis. A pilot study
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Peroxisome proliferator-activated receptor beta/delta exerts a strong protection from ischemic acute renal failure
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Protection of endothelial survival by peroxisome proliferator-activated receptor-delta mediated 14-3-3 upregulation
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Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)
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Control of T cell viability
1 reference
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Crossref
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7 January 2021
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7 January 2021
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Peroxisome proliferator-activated receptor delta (PPARdelta) activation protects H9c2 cardiomyoblasts from oxidative stress-induced apoptosis
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7 January 2021
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Activation of PPARbeta/delta induces endothelial cell proliferation and angiogenesis
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Inhibition of protein synthesis stimulates the transcription of human beta-interferon genes in Chinese hamster ovary cells
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PPARdelta enhances keratinocyte proliferation in psoriasis and induces heparin-binding EGF-like growth factor
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2008.32
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7 January 2021
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Critical roles of PPAR beta/delta in keratinocyte response to inflammation
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Expression and Localization of Peroxisome Proliferator-Activated Receptors and Nuclear Factor κB in Normal and Lesional Psoriatic Skin
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1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/JID.2008.32
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18305567
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18305567%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
Dimensions Publication ID
1030828100
0 references
PubMed publication ID
18305567
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18305567
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18305567%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
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