(Q81126965)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16127425%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

title

Analysis of the tight skin (Tsk1/+) mouse as a model for testing antifibrotic agents (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16127425%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

author name string

Ruth M Baxter

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16127425%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Thomas P Crowell

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16127425%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Margaret E McCrann

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16127425%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Erica M Frew

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16127425%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Humphrey Gardner

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16127425%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

publication date

1 October 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16127425%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

published in

Laboratory Investigation

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16127425%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

volume

85

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16127425%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

issue

10

1 reference

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6 January 2020

page(s)

1199-1209

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16127425%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/labinvest.3700331

6 January 2020

exact match

0 references

cites work

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7 January 2021

Fibrillin: monomers and microfibrils

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Fibrillin 1 abnormalities in dermal fibroblast cultures from first-degree relatives of patients with systemic sclerosis (scleroderma)

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Increased prevalence of systemic sclerosis in a Native American tribe in Oklahoma. Association with an Amerindian HLA haplotype

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7 January 2021

Association of microsatellite markers near the fibrillin 1 gene on human chromosome 15q with scleroderma in a Native American population

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7 January 2021

Autoantibodies to the extracellular matrix microfibrillar protein, fibrillin 1, in patients with localized scleroderma

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7 January 2021

Abnormalities in fibrillin 1-containing microfibrils in dermal fibroblast cultures from patients with systemic sclerosis (scleroderma)

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7 January 2021

Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein

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7 January 2021

Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome

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7 January 2021

Characterization of mutated protein encoded by partially duplicated fibrillin-1 gene in tight skin (TSK) mice

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7 January 2021

Molecular aspects of scleroderma

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7 January 2021

Biology of the scleroderma fibroblast

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7 January 2021

TGF-beta signaling and the fibrotic response

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7 January 2021

A tandem duplication within the fibrillin 1 gene is associated with the mouse tight skin mutation

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7 January 2021

The structure and tensile properties of the skin of tight-skin (Tsk) mutant mice

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7 January 2021

The ultrastructure of collagen in the dermis of tight-skin (Tsk) mutant mice

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7 January 2021

Scleroderma-like alterations in collagen metabolism occurring in the TSK (tight skin) mouse

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7 January 2021

Correlation between the concentration of serum anti-topoisomerase I autoantibodies and histological and biochemical alterations in the skin of tight skin mice

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7 January 2021

Genetic and immunologic features associated with scleroderma-like syndrome of TSK mice

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7 January 2021

Reduction in dermal fibrosis in the tight-skin (Tsk) mouse after local application of halofuginone

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7 January 2021

Lack of skin fibrosis in tight skin (TSK) mice with targeted mutation in the interleukin-4R alpha and transforming growth factor-beta genes.

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7 January 2021

Halofuginone, an inhibitor of type-I collagen synthesis and skin sclerosis, blocks transforming-growth-factor-beta-mediated Smad3 activation in fibroblasts.

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7 January 2021

Disrupting the IL-4 gene rescues mice homozygous for the tight-skin mutation from embryonic death and diminishes TGF-beta production by fibroblasts

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7 January 2021

Role of profibrogenic cytokines secreted by T cells in fibrotic processes in scleroderma

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7 January 2021

Inhibition of collagen synthesis and changes in skin morphology in murine graft-versus-host disease and tight skin mice: effect of halofuginone

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7 January 2021

New insights into the assembly of extracellular microfibrils from the analysis of the fibrillin 1 mutation in the tight skin mouse

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7 January 2021

Fibulin-2 and fibulin-5 alterations in tsk mice associated with disorganized hypodermal elastic fibers and skin tethering

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7 January 2021

A role for the androgen receptor in collagen content of the skin

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7 January 2021

Mutant fibrillin 1 from tight skin mice increases extracellular matrix incorporation of microfibril-associated glycoprotein 2 and type I collagen.

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7 January 2021

Activation of a fibroblast-specific enhancer of the proalpha2(I) collagen gene in tight-skin mice

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7 January 2021

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7 January 2021

Anti-IL-4 treatment prevents dermal collagen deposition in the tight-skin mouse model of scleroderma

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7 January 2021

Molecular mechanisms of interleukin-4-induced up-regulation of type I collagen gene expression in murine fibroblasts.

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7 January 2021