(Q81127020)

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Substrate cycling between de novo lipogenesis and lipid oxidation: a thermogenic mechanism against skeletal muscle lipotoxicity and glucolipotoxicity

scientific article published on 01 December 2004

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scholarly article

1 reference

Europe PubMed Central

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6 January 2020

1 reference

Europe PubMed Central

Substrate cycling between de novo lipogenesis and lipid oxidation: a thermogenic mechanism against skeletal muscle lipotoxicity and glucolipotoxicity (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592483%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Abdul G. Dulloo

1

1 reference

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6 January 2020

Giovanni Solinas

5

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6 January 2020

author name string

M Gubler

2

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6 January 2020

J P Montani

3

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6 January 2020

J Seydoux

4

1 reference

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6 January 2020

publication date

1 December 2004

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6 January 2020

28 Suppl 4

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6 January 2020

S29-37

1 reference

Europe PubMed Central

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6 January 2020

Type II diabetes, essential hypertension, and obesity as "syndromes of impaired genetic homeostasis": the "thrifty genotype" hypothesis enters the 21st century

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

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Insulin-mediated sympathetic stimulation: role in the pathogenesis of obesity-related hypertension (or, how insulin affects blood pressure, and why).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Pathogenesis of skeletal muscle insulin resistance in type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Decreased muscle glucose transport/phosphorylation is an early defect in the pathogenesis of non-insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Applications of NMR spectroscopy to study muscle glycogen metabolism in man.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Banting lecture 1988. Role of insulin resistance in human disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Plasma Amino Acid Levels and Insulin Secretion in Obesity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Pathways from obesity to diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Nutrient-induced insulin resistance in human skeletal muscle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Glucose-induced insulin resistance of skeletal-muscle glucose transport and uptake

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of intramuscular lipid in insulin resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Metabolism of amino-acids: Deamination of amino-acids

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of the Phosphofructokinase Reaction in Perfused Rat Heart by Respiration of Ketone Bodies, Fatty Acids and Pyruvate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of Fatty Acids, Ketone Bodies, Diabetes and Starvation on Pyruvate Metabolism in Rat Heart and Diaphragm Muscle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulatory interactions between lipids and carbohydrates: the glucose fatty acid cycle after 35 years.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of fatty acids on glucose production and utilization in man

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Interaction between glucose and free fatty acid metabolism in human skeletal muscle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanisms of fatty acid-induced inhibition of glucose uptake

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Interaction between free fatty acids and glucose metabolism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Lilly lecture 1995. Glucose transport: pivotal step in insulin action

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

A possible role for malonyl-CoA in the regulation of hepatic fatty acid oxidation and ketogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Glucose-fatty acid interactions in health and disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

The enzymic chain elongation of fatty acids by rat-liver microsomes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning of human acetyl-CoA carboxylase-beta and its unique features

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

The subcellular localization of acetyl-CoA carboxylase 2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Malonyl-CoA and the regulation of fatty acid oxidation in soleus muscle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Human fatty acid synthase: properties and molecular cloning

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation by insulin of gene expression in human skeletal muscle and adipose tissue. Evidence for specific defects in type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Human obesity and type 2 diabetes are associated with alterations in SREBP1 isoform expression that are reproduced ex vivo by tumor necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Sterol regulatory element binding protein-1c expression and action in rat muscles: insulin-like effects on the control of glycolytic and lipogenic enzymes and UCP3 gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Skeletal muscle sterol regulatory element binding protein-1c decreases with food deprivation and increases with feeding in rats.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Theta-isoform of PKC is required for alterations in cytoskeletal dynamics and barrier permeability in intestinal epithelium: a novel function for PKC-theta.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Glucose induces de novo lipogenesis in rat muscle satellite cells through a sterol-regulatory-element-binding-protein-1c-dependent pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Chronic hyperglycaemia promotes lipogenesis and triacylglycerol accumulation in human skeletal muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Entrainment of the diurnal rhythm of plasma leptin to meal timing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of the obese gene product on body weight regulation in ob/ob mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Weight-reducing effects of the plasma protein encoded by the obese gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Leptin rapidly lowers food intake and elevates metabolic rates in lean and ob/ob mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Low dose leptin administration reverses effects of sustained weight-reduction on energy expenditure and circulating concentrations of thyroid hormones

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Diseases of liporegulation: new perspective on obesity and related disorders

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Peripheral metabolic actions of leptin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Leptin Directly Alters Lipid Partitioning in Skeletal Muscle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Leptin directly stimulates thermogenesis in skeletal muscle.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

The direct effect of leptin on skeletal muscle thermogenesis is mediated by substrate cycling between de novo lipogenesis and lipid oxidation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

The activation of p38 MAPK by the beta-adrenergic agonist isoproterenol in rat epididymal fat cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of AMP-activated protein kinase in cyclic AMP-dependent lipolysis In 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Uptake of glucose and release of fatty acids and glycerol by rat brown adipose tissue in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Fuel selection in brown adipose tissue

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Cold elicits the simultaneous induction of fatty acid synthesis and beta-oxidation in murine brown adipose tissue: prediction from differential gene expression and confirmation in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Mice with targeted disruption of the Dio2 gene have cold-induced overexpression of the uncoupling protein 1 gene but fail to increase brown adipose tissue lipogenesis and adaptive thermogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

beta(3)-Adrenoceptor agonists: potential, pitfalls and progress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of UCP homologues in skeletal muscles and brown adipose tissue: mediators of thermogenesis or regulators of lipids as fuel substrate?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Adaptive thermogenesis and uncoupling proteins: a reappraisal of their roles in fat metabolism and energy balance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.IJO.0802861

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.IJO.0802861

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592483%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592483%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

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