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English
Fat storage in pancreas and in insulin-sensitive tissues in pathogenesis of type 2 diabetes
scientific article published on 01 December 2004
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
15592487
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592487%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
review article
1 reference
stated in
Europe PubMed Central
title
Fat storage in pancreas and in insulin-sensitive tissues in pathogenesis of type 2 diabetes
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
15592487
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592487%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
main subject
type 2 diabetes
1 reference
based on heuristic
inferred from title
author name string
F Assimacopoulos-Jeannet
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
15592487
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592487%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
publication date
1 December 2004
1 reference
stated in
Europe PubMed Central
PubMed ID
15592487
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592487%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
volume
28 Suppl 4
1 reference
stated in
Europe PubMed Central
PubMed ID
15592487
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592487%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
page(s)
S53-7
1 reference
stated in
Europe PubMed Central
PubMed ID
15592487
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592487%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
cites work
What if Minkowski had been ageusic? An alternative angle on diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nutritional effects of fat on carbohydrate metabolism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The stimulus-secretion coupling of glucose-induced insulin release: fuel metabolism in islets deprived of exogenous nutrient
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hole of plasma free fatty acids in the control of insulin secretion in man
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stimulation of insulin secretion by infusion of free fatty acids
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Opposite effects of short- and long-term fatty acid infusion on insulin secretion in healthy subjects.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The insulinotropic potency of fatty acids is influenced profoundly by their chain length and degree of saturation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signal transduction mechanisms in nutrient-induced insulin secretion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A fatty acid- dependent step is critically important for both glucose- and non-glucose-stimulated insulin secretion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beta-cell hypersensitivity to glucose following 24-h exposure of rat islets to fatty acids
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Uncoupling protein 2: a possible link between fatty acid excess and impaired glucose-induced insulin secretion?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glucose-induced preproinsulin gene expression is inhibited by the free fatty acid palmitate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long chain coenzyme A esters activate the pore-forming subunit (Kir6. 2) of the ATP-regulated potassium channel.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The composition of dietary fat directly influences glucose-stimulated insulin secretion in rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hormone-sensitive lipase, the rate-limiting enzyme in triglyceride hydrolysis, is expressed and active in beta-cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic effect of fatty acids on insulin release is not through the alteration of glucose metabolism in a pancreatic beta-cell line (beta HC9).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms decreasing glucose oxidation in diabetes and starvation: role of lipid fuels and hormones.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular mechanisms of insulin resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Muscle triglyceride and insulin resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Diet-induced muscle insulin resistance in rats is ameliorated by acute dietary lipid withdrawal or a single bout of exercise: parallel relationship between insulin stimulation of glucose uptake and suppression of long-chain fatty acyl-CoA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prolonged inhibition of muscle carnitine palmitoyltransferase-1 promotes intramyocellular lipid accumulation and insulin resistance in rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective fatty acid uptake modulates insulin responsiveness and metabolic responses to diet in CD36-null mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new antidiabetic agent, BRL 49653, reduces lipid availability and improves insulin action and glucoregulation in the rat.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased efficiency of fatty acid uptake contributes to lipid accumulation in skeletal muscle of high fat-fed insulin-resistant rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Acyl-CoA inhibition of hexokinase in rat and human skeletal muscle is a potential mechanism of lipid-induced insulin resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.IJO.0802857
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.IJO.0802857
1 reference
stated in
Europe PubMed Central
PubMed ID
15592487
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592487%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
PubMed ID
15592487
1 reference
stated in
Europe PubMed Central
PubMed ID
15592487
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592487%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
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