(Q81493978)

English

Activation of the transient receptor potential M2 channel and poly(ADP-ribose) polymerase is involved in oxidative stress-induced cardiomyocyte death

scientific article published in 2005

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scholarly article

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9 January 2020

Activation of the transient receptor potential M2 channel and poly(ADP-ribose) polymerase is involved in oxidative stress-induced cardiomyocyte death (English)

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9 January 2020

Chung-Liang Chien

4

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9 January 2020

5

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9 January 2020

6

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9 January 2020

author name string

Yang KT

1

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9 January 2020

Chang WL

2

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9 January 2020

Yang PC

3

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9 January 2020

Wu ML

7

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9 January 2020

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publication date

18 November 2005

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9 January 2020

Cell Death & Differentiation

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9 January 2020

13

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9 January 2020

10

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9 January 2020

1815-1826

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9 January 2020

https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401813

0 references

Marked reduction of free radical generation and contractile dysfunction by antioxidant therapy begun at the time of reperfusion. Evidence that myocardial "stunning" is a manifestation of reperfusion injury

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Molecular and cellular mechanisms of myocardial failure

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Apoptosis in human acute myocardial infarction

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The mitochondrial death pathway and cardiac myocyte apoptosis

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Marked reduction in myocardial infarct size due to prolonged infusion of an antioxidant during reperfusion

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Four deaths and a funeral: from caspases to alternative mechanisms.

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The central executioners of apoptosis: caspases or mitochondria?

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The mitochondrial permeability transition, release of cytochrome c and cell death. Correlation with the duration of pore openings in situ

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Mitochondria: releasing power for life and unleashing the machineries of death

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Mitochondria: a target for myocardial protection.

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Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis

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The therapeutic potential of poly(ADP-ribose) polymerase inhibitors

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Inhibitors of poly (ADP-ribose) synthetase protect rat cardiomyocytes against oxidant stress

1 reference

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7 January 2021

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Modes of myocardial cell injury and cell death in ischemic heart disease

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"Apoptotic" myocytes in infarct area in rabbit hearts may be oncotic myocytes with DNA fragmentation: analysis by immunogold electron microscopy combined with In situ nick end-labeling

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Cardiomyocyte death induced by myocardial ischemia and reperfusion: measurement with recombinant human annexin-V in a mouse model

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Ultrastructural morphological changes are not characteristic of apoptotic cell death following focal cerebral ischaemia in the rat.

1 reference

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The TRP channels, a remarkably functional family

1 reference

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TRP channels as cellular sensors

1 reference

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7 January 2021

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LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death

1 reference

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7 January 2021

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Activation of the cation channel long transient receptor potential channel 2 (LTRPC2) by hydrogen peroxide. A splice variant reveals a mode of activation independent of ADP-ribose.

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7 January 2021

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Critical intracellular Ca2+ dependence of transient receptor potential melastatin 2 (TRPM2) cation channel activation

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7 January 2021

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ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology

1 reference

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7 January 2021

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Immunocyte Ca2+ influx system mediated by LTRPC2.

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Mitochondrial permeability transition in hepatocytes induced by t-BuOOH: NAD(P)H and reactive oxygen species

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7 January 2021

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Poly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death

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7 January 2021

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Poly(ADP-ribose) catabolism in mammalian cells exposed to DNA-damaging agents

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Mitochondrial Na+ overload is caused by oxidative stress and leads to activation of the caspase 3- dependent apoptotic machinery.

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A "minimal" sodium channel construct consisting of ligated S5-P-S6 segments forms a toxin-activatable ionophore

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Early metabolic inhibition-induced intracellular sodium and calcium increase in rat cerebellar granule cells.

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Mitochondrial Ca(2+) uptake depends on the spatial and temporal profile of cytosolic Ca(2+) signals

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Oxygen-bridged dinuclear ruthenium amine complex specifically inhibits Ca2+ uptake into mitochondria in vitro and in situ in single cardiac myocytes

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Stimulation of endogenous endonuclease activity in hepatocytes exposed to oxidative stress

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Role of Ced-3/ICE-family proteases in staurosporine-induced programmed cell death

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A novel TRPM2 isoform inhibits calcium influx and susceptibility to cell death

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Inhibition of TRPM2 channels by the antifungal agents clotrimazole and econazole.

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A nuclear magnetic resonance study of metabolism in the ferret heart during hypoxia and inhibition of glycolysis

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Identifiers

10.1038/SJ.CDD.4401813

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16294211%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

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9 January 2020

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