(Q81521584)

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Preparation, preparation, preparation: The influence of adrenergic agonism in cardiac ventricular repolarisation assays used in preclinical drug development and drug safety pharmacology

scientific article published on 09 December 2004

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15767200%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Preparation, preparation, preparation: The influence of adrenergic agonism in cardiac ventricular repolarisation assays used in preclinical drug development and drug safety pharmacology (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15767200%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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Jules C Hancox

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15767200%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Michael J Curtis

2

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Europe PubMed Central

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9 January 2020

publication date

9 December 2004

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15767200%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Journal of Pharmacological and Toxicological Methods

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15767200%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

51

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9 January 2020

2

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9 January 2020

77-79

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15767200%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Repolarizing K+ currents in rabbit heart Purkinje cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2004.11.001

7 January 2021

Is cardiac IKs a relevant drug target?

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2004.11.001

7 January 2021

Protein kinase C enhances the rapidly activating delayed rectifier potassium current, IKr, through a reduction in C-type inactivation in guinea-pig ventricular myocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2004.11.001

7 January 2021

New preclinical guidelines on drug effects on ventricular repolarization: safety pharmacology comes of age.

1 reference

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7 January 2021

Role of the 293b-sensitive, slowly activating delayed rectifier potassium current, i(Ks), in pacemaker activity of rabbit isolated sino-atrial node cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2004.11.001

7 January 2021

Pharmacological block of the slow component of the outward delayed rectifier current (I(Ks)) fails to lengthen rabbit ventricular muscle QT(c) and action potential duration

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2004.11.001

7 January 2021

Both beta-adrenergic receptor stimulation and cardiac tissue type have important roles in elucidating the functional effects of I(Ks) channel blockers in vitro

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2004.11.001

7 January 2021

In vivo electrophysiological effects of a selective slow delayed-rectifier potassium channel blocker in anesthetized dogs: potential insights into class III actions

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2004.11.001

7 January 2021

Reconstruction of the repolarization process in cardiac Purkinje fibres based on voltage clamp measurements of membrane current

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2004.11.001

7 January 2021

Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2004.11.001

7 January 2021

Pharmacology of cardiac potassium channels.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2004.11.001

7 January 2021

Structural determinants and biophysical properties of HERG and KCNQ1 channel gating

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2004.11.001

7 January 2021

Review of the predictive value of the Langendorff heart model (Screenit system) in assessing the proarrhythmic potential of drugs

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2004.11.001

7 January 2021

Troubleshooting problems with in vitro screening of drugs for QT interval prolongation using HERG K+ channels expressed in mammalian cell lines and Xenopus oocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2004.11.001

7 January 2021

Identifiers

10.1016/J.VASCN.2004.11.001

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15767200%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15767200%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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