(Q81615621)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18616419%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

review article

1 reference

title

ZD4054: a specific endothelin A receptor antagonist with promising activity in metastatic castration-resistant prostate cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18616419%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference

Ruth Warren

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18616419%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Glenn Liu

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18616419%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

publication date

1 August 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18616419%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Investigational Drugs

10 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18616419%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18616419%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18616419%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

page(s)

1237-1245

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18616419%20AND%20SRC:MED&resulttype=core&format=json

Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

10 January 2020

cites work

1 reference

12 December 2020

Clinical states in prostate cancer: toward a dynamic model of disease progression

1 reference

12 December 2020

Expression of endothelin 1 and endothelin A receptor in ovarian carcinoma: evidence for an autocrine role in tumor growth.

1 reference

12 December 2020

Vascular endothelial growth factor and its correlation with angiogenesis and p53 expression in prostate cancer

1 reference

12 December 2020

New bone formation in an osteoblastic tumor model is increased by endothelin-1 overexpression and decreased by endothelin A receptor blockade

1 reference

12 December 2020

Enhanced endothelin ET(B) receptor down-regulation in human tumor cells

1 reference

12 December 2020

Role of endothelin-1 in neovascularization of ovarian carcinoma

1 reference

12 December 2020

Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer

1 reference

12 December 2020

Pharmacological characterization of YM598, an orally active and highly potent selective endothelin ETA receptor antagonist

1 reference

12 December 2020

Clinical approaches to osseous metastases in prostate cancer.

1 reference

12 December 2020

Progressive osteoporosis during androgen deprivation therapy for prostate cancer

1 reference

12 December 2020

Endothelin-1 induces tumor proteinase activation and invasiveness of ovarian carcinoma cells

1 reference

12 December 2020

Autocrine actions of endothelin-1 as a growth factor in human ovarian carcinoma cells

1 reference

12 December 2020

Pharmacokinetic and tolerability profile of once-daily zibotentan (ZD4054) in Japanese and Caucasian patients with hormone-resistant prostate cancer

1 reference

12 December 2020

Endothelins in health and disease: an overview

1 reference

12 December 2020

Atrasentan, an endothelin-receptor antagonist for refractory adenocarcinomas: safety and pharmacokinetics

1 reference

12 December 2020

Surrogate endpoints in clinical trials: definition and operational criteria

1 reference

12 December 2020

Endothelin-induced apoptosis of A375 human melanoma cells

1 reference

12 December 2020

Endothelin receptors as novel targets in tumor therapy

1 reference

12 December 2020

Endothelin-2 is a hypoxia-induced autocrine survival factor for breast tumor cells

1 reference

12 December 2020

Endothelins as autocrine regulators of tumor cell growth

1 reference

12 December 2020

Transactivation of the epidermal growth factor receptor in endothelin-1-induced mitogenic signaling in human ovarian carcinoma cells

1 reference

12 December 2020

Hydrocortisone with or without mitoxantrone in men with hormone-refractory prostate cancer: results of the cancer and leukemia group B 9182 study.

1 reference

12 December 2020

Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: requirement for Akt activation

1 reference

12 December 2020

Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo.

1 reference

12 December 2020

A randomized, placebo-controlled trial of zoledronic acid in patients with hormone-refractory metastatic prostate carcinoma

1 reference

12 December 2020

Suppression of prostate cancer induced bone remodeling by the endothelin receptor A antagonist atrasentan

1 reference

12 December 2020

Role of endothelin axis in progression to aggressive phenotype of prostate adenocarcinoma

1 reference

12 December 2020

Specific inhibition of the endothelin A receptor with ZD4054: clinical and pre-clinical evidence.

1 reference

12 December 2020

Effects of selective endothelin ET(A) receptor antagonists on endothelin-1-induced potentiation of cancer pain

1 reference

12 December 2020

Bone loss in men with prostate cancer treated with gonadotropin-releasing hormone agonists

1 reference

12 December 2020

Expression of endothelin receptor a associated with prostate cancer progression

1 reference

12 December 2020

Therapeutic targeting of the endothelin a receptor in human ovarian carcinoma.

1 reference

12 December 2020

Identification of endothelin–1 in the pathophysiology of metastatic adenocarcinoma of the prostate

1 reference

12 December 2020

Regional haemodynamic effects of endothelin-1 in rat and man: unexpected adverse reaction

1 reference

12 December 2020

Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology.

1 reference

12 December 2020

Osteoblasts in prostate cancer metastasis to bone

1 reference

12 December 2020

Chemotherapy with mitoxantrone plus prednisone or prednisone alone for symptomatic hormone-resistant prostate cancer: a Canadian randomized trial with palliative end points.

1 reference

12 December 2020

Randomized phase II study of atrasentan alone or in combination with zoledronic acid in men with metastatic prostate cancer

1 reference

12 December 2020

The endothelin axis: emerging role in cancer

1 reference

12 December 2020

Expression and localization of endothelin receptors: implications for the involvement of peripheral glia in nociception

1 reference

12 December 2020

Prostate cancer clinical trial end points: "RECIST"ing a step backwards.

1 reference

12 December 2020

Effect of endothelin-A receptor blockade with atrasentan on tumor progression in men with hormone-refractory prostate cancer: a randomized, phase II, placebo-controlled trial

1 reference

12 December 2020

Endothelin-1 as a target for therapeutic intervention in prostate cancer

1 reference

12 December 2020

Dose-ranging study of the safety and pharmacokinetics of atrasentan in patients with refractory malignancies

1 reference

12 December 2020

Methylation of the 5' CpG island of the endothelin B receptor gene is common in human prostate cancer.

1 reference

12 December 2020

Endothelin-1 induces vascular endothelial growth factor by increasing hypoxia-inducible factor-1alpha in ovarian carcinoma cells.

1 reference

12 December 2020

Pharmacological characterization of A-127722: an orally active and highly potent ETA-selective receptor antagonist.

1 reference

12 December 2020

Prostate-specific antigen and pain surrogacy analysis in metastatic hormone-refractory prostate cancer

1 reference

12 December 2020

Endothelin-1 promotes proteolytic activity of ovarian carcinoma

1 reference

12 December 2020

Endothelin-1 production and decreased endothelin B receptor expression in advanced prostate cancer

1 reference

12 December 2020

Metastatic patterns of prostatic cancer. Correlation between sites and number of organs involved

1 reference

12 December 2020

Endothelin-1 from prostate cancer cells is enhanced by bone contact which blocks osteoclastic bone resorption

1 reference

12 December 2020

Endothelin Inhibition: Novel Therapy for Prostate Cancer

1 reference

12 December 2020

A phase 3 randomized controlled trial of the efficacy and safety of atrasentan in men with metastatic hormone-refractory prostate cancer.

1 reference

12 December 2020

Phase I dose-escalation study of the safety and pharmacokinetics of atrasentan: an endothelin receptor antagonist for refractory prostate cancer.

1 reference

12 December 2020

Endothelin-1 decreases gap junctional intercellular communication by inducing phosphorylation of connexin 43 in human ovarian carcinoma cells

1 reference

12 December 2020

Endothelin receptor antagonists in cancer therapy

1 reference

12 December 2020

Growth inhibition of cervix carcinoma cells in vivo by endothelin A receptor blockade

1 reference

12 December 2020

Endothelin-B receptor activation triggers an endogenous analgesic cascade at sites of peripheral injury

1 reference

12 December 2020

1 reference

12 December 2020

Endothelin receptor antagonists in the treatment of prostate cancer

1 reference

12 December 2020

Cancer statistics, 2007

1 reference

12 December 2020

An endothelin receptor B antagonist inhibits growth and induces cell death in human melanoma cells in vitro and in vivo

1 reference

12 December 2020

Activation of mitogenic signaling by endothelin 1 in ovarian carcinoma cells

1 reference

12 December 2020

10.1517/13543784.17.8.1237

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18616419%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18616419%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

PubMed publication ID

18616419

1 reference