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To kill or be killed: how HIV exhausts the immune system
scientific article published on 01 August 2005
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1 reference
stated in
Europe PubMed Central
PubMed publication ID
15832178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15832178%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
title
To kill or be killed: how HIV exhausts the immune system
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15832178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15832178%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
author name string
Gougeon ML
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15832178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15832178%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
publication date
1 August 2005
1 reference
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Europe PubMed Central
PubMed publication ID
15832178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15832178%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
published in
Cell Death & Differentiation
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15832178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15832178%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
volume
12 Suppl 1
1 reference
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Europe PubMed Central
PubMed publication ID
15832178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15832178%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
page(s)
845-854
1 reference
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Europe PubMed Central
PubMed publication ID
15832178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15832178%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
exact match
https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401616
0 references
cites work
HIV preferentially infects HIV-specific CD4+ T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The dynamics of CD4+ T-cell depletion in HIV disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis in AIDS
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Programmed death of T cells in HIV-1 infection
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chemokine receptors and HIV entry
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dynamics of CCR5 expression by CD4(+) T cells in lymphoid tissues during simian immunodeficiency virus infection
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
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inferred from DOI database lookup
Cellular immune responses to HIV.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gene expression profiling of host response in models of acute HIV infection
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rapid and irreversible CD4+ T-cell depletion induced by the highly pathogenic simian/human immunodeficiency virus SHIV(DH12R) is systemic and synchronous
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impact of HIV-1 infection and highly active antiretroviral therapy on the kinetics of CD4+ and CD8+ T cell turnover in HIV-infected patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long-term kinetics of T cell production in HIV-infected subjects treated with highly active antiretroviral therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetics of CD4+ T cell repopulation of lymphoid tissues after treatment of HIV-1 infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Changes in thymic function with age and during the treatment of HIV infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for increased T cell turnover and decreased thymic output in HIV infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of "tissue" transglutaminase in HIV pathogenesis: evidence for high rate of apoptosis of CD4+ T lymphocytes and accessory cells in lymphoid tissues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
AIDS retrovirus induced cytopathology: giant cell formation and involvement of CD4 antigen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis as a mechanism of cell death in cultured T lymphoblasts acutely infected with HIV-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cytopathic effect of HIV is associated with apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo dynamics of T cell activation, proliferation, and death in HIV-1 infection: why are CD4+ but not CD8+ T cells depleted?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the HTLV-III/LAV envelope in syncytium formation and cytopathicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Contagious apoptosis facilitated by the HIV-1 envelope: fusion-induced cell-to-cell transmission of a lethal signal
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytopathic killing of peripheral blood CD4(+) T lymphocytes by human immunodeficiency virus type 1 appears necrotic rather than apoptotic and does not require env.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CXCR4 and CD4 mediate a rapid CD95-independent cell death in CD4(+) T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1 envelope induces activation of caspase-3 and cleavage of focal adhesion kinase in primary human CD4(+) T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-gp120 induced cell death in hematopoietic progenitor CD34+ cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cardiomyocytes undergo apoptosis in human immunodeficiency virus cardiomyopathy through mitochondrion- and death receptor-controlled pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1 Tat protein concomitantly down-regulates apical caspase-10 and up-regulates c-FLIP in lymphoid T cells: a potential molecular mechanism to escape TRAIL cytotoxicity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Monocytes treated with human immunodeficiency virus Tat kill uninfected CD4(+) cells by a tumor necrosis factor-related apoptosis-induced ligand-mediated mechanism.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1 Tat-mediated apoptosis in human brain microvascular endothelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 Tat induces apoptosis and increases sensitivity to apoptotic signals by up-regulating FLICE/caspase-8.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 vpr induces apoptosis through caspase activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis enhancement by the HIV-1 Nef protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis mediated by HIV protease is preceded by cleavage of Bcl-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of Nef-CXCR4 interactions important for apoptosis induction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 Nef and p56lck protein-tyrosine kinase interact with a common element in CD4 cytoplasmic tail
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD95's deadly mission in the immune system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-specific CD8+ T cells exhibit markedly reduced levels of Bcl-2 and Bcl-xL.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The expression of Fas Ligand by macrophages and its upregulation by human immunodeficiency virus infection.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potential deleterious effect of anti-viral cytotoxic lymphocyte through the CD95 (FAS/APO-1)-mediated pathway during chronic HIV infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased sensitivity of T lymphocytes to tumor necrosis factor receptor 1 (TNFR1)- and TNFR2-mediated apoptosis in HIV infection: relation to expression of Bcl-2 and active caspase-8 and caspase-3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immune control of HIV-1 after early treatment of acute infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Plasmacytoid dendritic cells are highly susceptible to human immunodeficiency virus type 1 infection and release infectious virus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-infected Langerhans cells preferentially transmit virus to proliferating autologous CD4+ memory T cells located within Langerhans cell-T cell clusters
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High-level HIV-1 viremia suppresses viral antigen-specific CD4(+) T cell proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
AIDS virus-specific cytotoxic T lymphocytes in lung disorders
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Quantitation of HIV-1-Specific Cytotoxic T Lymphocytes and Plasma Load of Viral RNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The selective increase in caspase-3 expression in effector but not memory T cells allows susceptibility to apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transdifferentiation comes of age
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation, survival and apoptosis of CD45RO+ and CD45RO- T cells of human immunodeficiency virus-infected individuals: effects of interleukin-15 and comparison with interleukin-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential effects of interleukin-7 and interleukin-15 on NK cell anti-human immunodeficiency virus activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IL-15 enhances survival and function of HIV-specific CD8+ T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of IL-7 on early human thymocyte progenitor cells in vitro and in SCID-hu Thy/Liv mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IL-7 Stimulates T Cell Renewal Without Increasing Viral Replication in Simian Immunodeficiency Virus-Infected Macaques
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Elevated interleukin-7 levels not sufficient to maintain T-cell homeostasis during simian immunodeficiency virus–induced disease progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stromal cell-derived factor 1/CXCR4 signaling is critical for early human T-cell development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-7-treated naive T cells can be productively infected by T-cell-adapted and primary isolates of human immunodeficiency virus 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of control of T cell apoptosis under HAART. Influence of therapy regimen in vivo and in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association between altered expression of adipogenic factor SREBP1 in lipoatrophic adipose tissue from HIV-1-infected patients and abnormal adipocyte differentiation and insulin resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Influence of mitochondrial control of apoptosis on the pathogenesis, complications and treatment of HIV infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased thymic mass and circulating naive CD4 T cells in HIV-1-infected adults treated with growth hormone.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structured intermittent treatment for HIV disease: Necessary concession or premature compromise?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401616
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.CDD.4401616
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15832178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15832178%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
PubMed publication ID
15832178
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15832178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15832178%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
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