(Q81721889)

English

Determination and modelling of stereoselective interactions of ligands with drug transporters: a key dimension in the understanding of drug disposition

scientific article published on 01 July 2008

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18668426%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

1 reference

Europe PubMed Central

Determination and modelling of stereoselective interactions of ligands with drug transporters: a key dimension in the understanding of drug disposition (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18668426%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

stereoselectivity

1 reference

based on heuristic

inferred from title

Michal Kolinski

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18668426%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Krzysztof Jóźwiak

1 reference

ORCID Public Data File 2021

author name string

P Bhatia

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18668426%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

R Moaddel

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18668426%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

K Jozwiak

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18668426%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

I W Wainer

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18668426%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

publication date

1 July 2008

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18668426%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18668426%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

38

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18668426%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

7-8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18668426%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

656-675

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18668426%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Affinities at the verapamil binding site of MDR1-encoded P-glycoprotein: drugs and analogs, stereoisomers and metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The synthesis and initial characterization of an immobilized purinergic receptor (P2Y1) liquid chromatography stationary phase for online screening

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereoisomers of calcium antagonists which differ markedly in their potencies as calcium blockers are equally effective in modulating drug transport by P-glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacophore modelling of stereoselective binding to the human organic cation transporter (hOCT1).

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of racemic mefloquine and its enantiomers with P-glycoprotein in an immortalised rat brain capillary endothelial cell line, GPNT.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of P-glycoprotein substrates using open tubular chromatography on an immobilized P-glycoprotein column: Comparison of chromatographic results with Caco-2 permeability

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and functional activity of the ABC-transporter proteins P-glycoprotein and multidrug-resistance protein 1 in human brain tumor cells and astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Future directions for drug transporter modelling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereoselective transport of hydrophilic quaternary drugs by human MDR1 and rat Mdr1b P-glycoproteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural features determining activity of phenothiazines and related drugs for inhibition of cell growth and reversal of multidrug resistance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allosteric modifiers of neuronal nicotinic acetylcholine receptors: new methods, new opportunities.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interaction of n-tetraalkylammonium compounds with a human organic cation transporter, hOCT1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single amino acid residue contributes to distinct mechanisms of inhibition of the human multidrug transporter by stereoisomers of the dopamine receptor antagonist flupentixol.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G-protein-coupled receptor chromatographic stationary phases. 2. Ligand-induced conformational mobility in an immobilized beta2-adrenergic receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of an immobilized P-glycoprotein stationary phase for on-line liquid chromatographic determination of drug-binding affinities

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Computational approaches to modeling drug transporters.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of noncompetitive inhibitors with the alpha3beta2 nicotinic acetylcholine receptor investigated by affinity chromatography and molecular docking.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organic cation transporters

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional and pharmacological characterization of human Na(+)-carnitine cotransporter hOCTN2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of molecular structure on substrate binding to the human organic cation transporter, hOCT1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal agent inhibition of the multidrug resistance pump in human leukemic lymphoblasts.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

D-verapamil and L-verapamil are equally effective in increasing vincristine accumulation in leukemic cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of noncompetitive inhibitors with an immobilized alpha3beta4 nicotinic acetylcholine receptor investigated by affinity chromatography, quantitative-structure activity relationship analysis, and molecular docking

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Application of three-dimensional quantitative structure-activity relationships of P-glycoprotein inhibitors and substrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MDA435/LCC6 and MDA435/LCC6MDR1: ascites models of human breast cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical Studies with Modulators of Multidrug Resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Competitive and allosteric interactions in ligand binding to P-glycoprotein as observed on an immobilized P-glycoprotein liquid chromatographic stationary phase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enantioselective binding to the human organic cation transporter-1 (hOCT1) determined using an immobilized hOCT1 liquid chromatographic stationary phase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The enantioselective binding of mefloquine enantiomers to P-glycoprotein determined using an immobilized P-glycoprotein liquid chromatographic stationary phase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of immobilized membrane-based affinity columns for use in the online characterization of membrane bound proteins and for targeted affinity isolations

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa)

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Centrifugal and chromatographic analyses of tryptophan and tyrosine uptake by red blood cells and GLUT1 proteoliposomes with permeability estimates and observations on dihydrocytochalasin B.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secondary and tertiary structure changes of reconstituted P-glycoprotein. A Fourier transform attenuated total reflection infrared spectroscopy analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development and characterization of immobilized human organic anion transporter-based liquid chromatographic stationary phase: hOAT1 and hOAT2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development and characterization of an immobilized human organic cation transporter based liquid chromatographic stationary phase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18668426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1080/00498250802109207

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18668426%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18668426%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18668426%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

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