(Q82260003)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22038016%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

MK886 inhibits the proliferation of HL-60 leukemia cells by suppressing the expression of mPGES-1 and reducing prostaglandin E2 synthesis (English)

1 reference

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15 January 2020

1 reference

YiQing Li

1

1 reference

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15 January 2020

SongMei Yin

2

1 reference

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15 January 2020

DaNian Nie

3

1 reference

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15 January 2020

ShuangFeng Xie

4

1 reference

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15 January 2020

LiPing Ma

5

1 reference

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15 January 2020

XiuJu Wang

6

1 reference

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15 January 2020

YuDan Wu

7

1 reference

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15 January 2020

Jie Xiao

8

1 reference

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15 January 2020

publication date

29 October 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22038016%20AND%20SRC:MED&resulttype=core&format=json

International Journal of Hematology

15 January 2020

published in

1 reference

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15 January 2020

volume

94

1 reference

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15 January 2020

issue

5

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15 January 2020

page(s)

472-478

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https://scigraph.springernature.com/pub.10.1007/s12185-011-0954-0

15 January 2020

exact match

0 references

cites work

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Microsomal prostaglandin E synthase-1: the inducible synthase for prostaglandin E2

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Results of a HOVON/SAKK donor versus no-donor analysis of myeloablative HLA-identical sibling stem cell transplantation in first remission acute myeloid leukemia in young and middle-aged adults: benefits for whom?

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The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment

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Monocytic differentiation of leukemic HL-60 cells induced by co-treatment with TNF-alpha and MK886 requires activation of pro-apoptotic machinery

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EP4 mediates PGE2 dependent cell survival through the PI3 kinase/AKT pathway

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12 December 2020

The 5-lipoxygenase-activating protein (FLAP) inhibitor, MK886, induces apoptosis independently of FLAP.

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Prostaglandin E receptors

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Clinical implications of microsomal prostaglandin e synthase-1 overexpression in human non-small-cell lung cancer.

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Regulation of caspase-3 and -9 activation in oxidant stress to RTE by forkhead transcription factors, Bcl-2 proteins, and MAP kinases

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Ingenuity network-assisted transcription profiling: Identification of a new pharmacologic mechanism for MK886.

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Prostaglandin E2 promotes migration and adhesion in hepatocellular carcinoma cells.

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Survival of acute myeloid leukemia cells requires PI3 kinase activation

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MK886-induced apoptosis depends on the 5-LO expression level in human malignant glioma cells

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12 December 2020

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Microsomal prostaglandin E2 synthase-1 in breast cancer: a potential target for therapy

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12 December 2020

Inhibitors of the inducible microsomal prostaglandin E2 synthase (mPGES-1) derived from MK-886.

1 reference

12 December 2020

The phosphoinositide 3-kinase pathway

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12 December 2020

The effects of cyclooxygenase2-prostaglandinE2 pathway on Helicobacter pylori-induced urokinase-type plasminogen activator system in the gastric cancer cells

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