(Q82488439)

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Epithelial-to-mesenchymal transition in cyst lining epithelial cells in an orthologous PCK rat model of autosomal-recessive polycystic kidney disease

scientific article published on November 17, 2010

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Europe PubMed Central

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16 January 2020

Epithelial-to-mesenchymal transition in cyst lining epithelial cells in an orthologous PCK rat model of autosomal-recessive polycystic kidney disease (English)

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16 January 2020

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polycystic kidney disease

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inferred from title

Koichi Nakanishi

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Koichi Nakanishi

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28 August 2024

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Shizuko Nagao

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28 August 2024

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Hiroko Togawa

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16 January 2020

Hironobu Mukaiyama

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16 January 2020

Taketsugu Hama

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16 January 2020

Yuko Shima

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16 January 2020

Mayumi Sako

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16 January 2020

Masayasu Miyajima

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16 January 2020

Kandai Nozu

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16 January 2020

Kazuhiro Nishii

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16 January 2020

Hisahide Takahashi

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16 January 2020

Kazumoto Iijima

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16 January 2020

Norishige Yoshikawa

13

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16 January 2020

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28 August 2024

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17 November 2010

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16 January 2020

full work available at URL

http://intl-ajprenal.physiology.org/cgi/content/abstract/300/2/F511

online access status

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28 August 2024

https://www.physiology.org/doi/pdf/10.1152/ajprenal.00038.2010

1 reference

10.1152/AJPRENAL.00038.2010

https://api.crossref.org/works/10.1152/AJPRENAL.00038.2010

28 August 2024

American Journal of Physiology - Renal Physiology

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16 January 2020

300

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16 January 2020

2

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16 January 2020

F511-20

1 reference

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16 January 2020

Loss of GLIS2 causes nephronophthisis in humans and mice by increased apoptosis and fibrosis

1

1 reference

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Abnormal sodium pump distribution during renal tubulogenesis in congenital murine polycystic kidney disease

3

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The Snail genes as inducers of cell movement and survival: implications in development and cancer.

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Wnt signaling in polycystic kidney disease

5

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Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney

6

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10.1152/AJPRENAL.00038.2010

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28 August 2024

The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression

7

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28 August 2024

Compromised cytoarchitecture and polarized trafficking in autosomal dominant polycystic kidney disease cells

8

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TGF-beta mediated epithelial-mesenchymal transition in autosomal dominant polycystic kidney disease

9

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Proteolytic cleavage and nuclear translocation of fibrocystin is regulated by intracellular Ca2+ and activation of protein kinase C.

12

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Polycystin-1, the PKD1 gene product, is in a complex containing E-cadherin and the catenins

13

1 reference

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28 August 2024

Evidence that fibroblasts derive from epithelium during tissue fibrosis

14

1 reference

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28 August 2024

Characterization of a novel polycystic kidney rat model with accompanying polycystic liver

15

1 reference

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28 August 2024

The pck rat: a new model that resembles human autosomal dominant polycystic kidney and liver disease

16

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Epithelial to mesenchymal transition in renal fibrogenesis: pathologic significance, molecular mechanism, and therapeutic intervention

17

1 reference

10.1152/AJPRENAL.00038.2010

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Defects in cholangiocyte fibrocystin expression and ciliary structure in the PCK rat.

18

1 reference

10.1152/AJPRENAL.00038.2010

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28 August 2024

Polyductin, the PKHD1 gene product, comprises isoforms expressed in plasma membrane, primary cilium, and cytoplasm

19

1 reference

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28 August 2024

New insights into the molecular pathophysiology of polycystic kidney disease

20

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Pioglitazone improves the phenotype and molecular defects of a targeted Pkd1 mutant

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Fibrocystin interacts with CAML, a protein involved in Ca2+ signaling

22

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Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

23

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Albumin induces endoplasmic reticulum stress and apoptosis in renal proximal tubular cells

24

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Progressive renal fibrosis in murine polycystic kidney disease: an immunohistochemical observation

25

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Molecular pathogenesis of ADPKD: the polycystin complex gets complex

26

1 reference

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PKHD1, the polycystic kidney and hepatic disease 1 gene, encodes a novel large protein containing multiple immunoglobulin-like plexin-transcription-factor domains and parallel beta-helix 1 repeats

27

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Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat.

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Differential expression of E-cadherin, N-cadherin and beta-catenin in proximal and distal segments of the rat nephron

29

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Modeling ciliopathies: Primary cilia in development and disease

30

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10.1152/AJPRENAL.00038.2010

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Attenuated expression of epithelial cell adhesion molecules in murine polycystic kidney disease

31

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A polycystin-1 multiprotein complex is disrupted in polycystic kidney disease cells

32

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Cholangiocytes with mesenchymal features contribute to progressive hepatic fibrosis of the polycystic kidney rat

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Gene profiling of polycystic kidneys.

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Systems biology of autosomal dominant polycystic kidney disease (ADPKD): computational identification of gene expression pathways and integrated regulatory networks

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Nuclear localization of beta-catenin and loss of apical brush border actin in cystic tubules of bcl-2 -/- mice

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Molecular and cellular pathophysiology of autosomal recessive polycystic kidney disease (ARPKD).

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Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease

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Complex networks orchestrate epithelial-mesenchymal transitions

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Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2

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Fibrocystin/polyductin, found in the same protein complex with polycystin-2, regulates calcium responses in kidney epithelia.

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The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein

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The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia

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PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells

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Identifiers

10.1152/AJPRENAL.00038.2010

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21084407%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21084407%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

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