(Q82672455)

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In vitro experimental (211)At-anti-CD33 antibody therapy of leukaemia cells overcomes cellular resistance seen in vivo against gemtuzumab ozogamicin

scientific article published on 27 January 2010

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107790%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

In vitro experimental (211)At-anti-CD33 antibody therapy of leukaemia cells overcomes cellular resistance seen in vivo against gemtuzumab ozogamicin (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107790%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Thorsten Petrich

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107790%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Zekiye Korkmaz

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107790%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Doris Krull

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107790%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Cornelia Frömke

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107790%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Geerd J Meyer

5

1 reference

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PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107790%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Wolfram H Knapp

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107790%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

publication date

27 January 2010

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107790%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

number of pages

11

1 reference

based on heuristic

inferred from page(s)

European Journal of Nuclear Medicine and Molecular Imaging

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107790%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

37

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107790%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107790%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

851-861

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107790%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

https://scigraph.springernature.com/pub.10.1007/s00259-009-1356-x

0 references

Radioimmunotherapy with alpha-emitting nuclides

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraperitoneal alpha-particle radioimmunotherapy of ovarian cancer patients: pharmacokinetics and dosimetry of (211)At-MX35 F(ab')2--a phase I study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The molecular biology of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase I trial of monoclonal antibody M195 in acute myelogenous leukemia: specific bone marrow targeting and internalization of radionuclide

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Administered activity and metastatic cure probability during radioimmunotherapy of ovarian cancer in nude mice with 211At-MX35 F(ab')2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of extranuclear cell sensitivity to alpha-particle radiation using a microdosimetric model. II. Application of the microdosimetric model to experimental results.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Breaking Chemoresistance and Radioresistance with [213Bi]anti-CD45 Antibodies in Leukemia Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calicheamicin-conjugated humanized anti-CD33 monoclonal antibody (gemtuzumab zogamicin, CMA-676) shows cytocidal effect on CD33-positive leukemia cell lines, but is inactive on P-glycoprotein-expressing sublines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Murine and humanized constructs of monoclonal antibody M195 (anti-CD33) for the therapy of acute myelogenous leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential response of human acute myeloid leukemia cells to gemtuzumab ozogamicin in vitro: role of Chk1 and Chk2 phosphorylation and caspase 3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment of radioactive astatine and iodine uptake in cancer cell lines expressing the human sodium/iodide symporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gemtuzumab ozogamicin-associated sinusoidal obstructive syndrome (SOS): an overview from the research on adverse drug events and reports (RADAR) project

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astatination of proteins using an N-succinimidyl tri-n-butylstannyl benzoate intermediate

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspases: killer proteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD33 expression and P-glycoprotein-mediated drug efflux inversely correlate and predict clinical outcome in patients with acute myeloid leukemia treated with gemtuzumab ozogamicin monotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical experience with alpha-particle emitting 211At: treatment of recurrent brain tumor patients with 211At-labeled chimeric antitenascin monoclonal antibody 81C6

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experience with gemtuzumab ozogamycin ("mylotarg") and all-trans retinoic acid in untreated acute promyelocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mylotarg (gemtuzumab ozogamicin) therapy is associated with hepatic venoocclusive disease in patients who have not received stem cell transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fifty years of clinical research by the leukemia committee of the cancer and leukemia group B.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD33-directed therapy with gemtuzumab ozogamicin in acute myeloid leukemia: progress in understanding cytotoxicity and potential mechanisms of drug resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The peripheral benzodiazepine receptor ligand PK11195 overcomes different resistance mechanisms to sensitize AML cells to gemtuzumab ozogamicin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell surface antigen and molecular targeting in the treatment of hematologic malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Streptavidin in antibody pretargeting. 5. chemical modification of recombinant streptavidin for labeling with the alpha-particle-emitting radionuclides 213Bi and 211At

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of gemtuzumab ozogamicin in acute leukaemia therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted alpha-particle radiotherapy with 211At-labeled monoclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calicheamicin gamma 1I: an antitumor antibiotic that cleaves double-stranded DNA site specifically

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic sinusoidal obstruction after gemtuzumab ozogamicin (Mylotarg) therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiation-Induced DNA Damage as a Predictor of Long-Term Toxicity in Locally Advanced Breast Cancer Patients Treated with High-Dose Hyperfractionated Radical Radiotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multidrug resistance protein attenuates gemtuzumab ozogamicin-induced cytotoxicity in acute myeloid leukemia cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An anti-CD33 antibody-calicheamicin conjugate for treatment of acute myeloid leukemia. Choice of linker

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gemtuzumab ozogamicin (Mylotarg) as a single agent for molecularly relapsed acute promyelocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biodistributions, myelosuppression, and toxicities in mice treated with an anti-CD45 antibody labeled with the alpha-emitting radionuclides bismuth-213 or astatine-211

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic efficacy of astatine-211-labeled trastuzumab on radioresistant SKOV-3 tumors in nude mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of DNA double strand break repair and chromosome aberration formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting of the CD33-calicheamicin immunoconjugate Mylotarg (CMA-676) in acute myeloid leukemia: in vivo and in vitro saturation and internalization by leukemic and normal myeloid cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effective treatment of established human breast tumor xenografts in immunodeficient mice with a single dose of the alpha-emitting radioisotope astatine-211 conjugated to anti-HER2/neu diabodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage behavior of calicheamicin gamma 1 and calicheamicin T

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preparation and in vivo evaluation of novel linkers for 211At labeling of proteins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Internalization and cell cycle-dependent killing of leukemic cells by Gemtuzumab Ozogamicin: rationale for efficacy in CD33-negative malignancies with endocytic capacity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiobiology of alpha particles. III. Cell inactivation by alpha-particle traversals of the cell nucleus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A (238)Pu irradiator for exposure of cultured cells with alpha-radiation: construction, calibration and dosimetry.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug therapy for acute myeloid leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Current applications of monoclonal antibodies for the therapy of hematopoietic cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA damage and prediction of radiation response in lymphocytes and epidermal skin human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct procedure for the production of 211At-labeled antibodies with an epsilon-lysyl-3-(trimethylstannyl)benzamide immunoconjugate

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preparation and evaluation of 211At labelled antineoplastic antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20107790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00259-009-1356-X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107790%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20107790%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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