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E2A is a transcriptional regulator of CD38 expression in chronic lymphocytic leukemia
scientific article published on 07 January 2011
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scholarly article
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Europe PubMed Central
PubMed ID
21212793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21212793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
title
E2A is a transcriptional regulator of CD38 expression in chronic lymphocytic leukemia
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
21212793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21212793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
main subject
chronic lymphocytic leukemia
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inferred from title
author
Tiziana Vaisitti
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
21212793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21212793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
Fabio Malavasi
series ordinal
6
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stated in
Europe PubMed Central
PubMed ID
21212793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21212793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
author name string
I Saborit-Villarroya
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
21212793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21212793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
D Rossi
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3
1 reference
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Europe PubMed Central
PubMed ID
21212793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21212793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
G D'Arena
series ordinal
4
1 reference
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Europe PubMed Central
PubMed ID
21212793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21212793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
G Gaidano
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed ID
21212793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21212793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
S Deaglio
series ordinal
7
1 reference
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Europe PubMed Central
PubMed ID
21212793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21212793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
publication date
7 January 2011
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Europe PubMed Central
PubMed ID
21212793
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21212793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
published in
Leukemia
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stated in
Europe PubMed Central
PubMed ID
21212793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21212793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
volume
25
1 reference
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Europe PubMed Central
PubMed ID
21212793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21212793%20AND%20SRC:MED&resulttype=core&format=json
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19 January 2020
issue
3
1 reference
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Europe PubMed Central
PubMed ID
21212793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21212793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
page(s)
479-488
1 reference
stated in
Europe PubMed Central
PubMed ID
21212793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21212793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
exact match
https://scigraph.springernature.com/pub.10.1038/leu.2010.291
0 references
cites work
Chronic lymphocytic leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intrinsic and extrinsic factors influencing the clinical course of B-cell chronic lymphocytic leukemia: prognostic markers with pathogenetic relevance
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In-tandem insight from basic science combined with clinical research: CD38 as both marker and key component of the pathogenetic network underlying chronic lymphocytic leukemia.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD38/CD31 interactions activate genetic pathways leading to proliferation and migration in chronic lymphocytic leukemia cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD38 expression in chronic lymphocytic leukemia is regulated by the tumor microenvironment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD38 on B-cell chronic lymphocytic leukemia cells has higher expression in lymph nodes than in peripheral blood or bone marrow.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD38 is a signaling molecule in B-cell chronic lymphocytic leukemia cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of CD38 in proliferating chronic lymphocytic leukemia cells stimulated with CD154 and interleukin-4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Toll-like receptors on B-CLL cells: expression and functional consequences of their stimulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bi-directional activation between mesenchymal stem cells and CLL B-cells: implication for CLL disease progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The metamorphosis of a molecule: from soluble enzyme to the leukocyte receptor CD38.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human CD38 gene: polymorphism, CpG island, and linkage to the CD157 (BST-1) gene.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD38 polymorphisms in Spanish patients with systemic lupus erythematosus
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD38 is associated with premenopausal and postmenopausal bone mineral density and postmenopausal bone loss
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD38 gene polymorphisms contribute to genetic susceptibility to B-cell chronic lymphocytic leukemia: evidence from two case-control studies in Polish Caucasians.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD38 gene polymorphism and chronic lymphocytic leukemia: a role in transformation to Richter syndrome?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E and ID proteins branch out.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation and function of the E2A proteins in B cell development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of E2A target genes in B lymphocyte development by using a gene tagging-based chromatin immunoprecipitation system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A conserved transcriptional enhancer regulates RAG gene expression in developing B cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD38 and ZAP-70 are functionally linked and mark CLL cells with high migratory potential
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transcriptional regulation of B cell lineage commitment.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Helix-loop-helix proteins and lymphocyte development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Decreased E47 in senescent B cell precursors is stage specific and regulated posttranslationally by protein turnover
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2A expression, nuclear localization, and in vivo formation of DNA- and non-DNA-binding species during B-cell development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polymorphism in the P2X7 receptor gene and survival in chronic lymphocytic leukaemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A loss-of-function polymorphic mutation in the cytolytic P2X7 receptor gene and chronic lymphocytic leukaemia: a molecular study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methylenetetrahydrofolate reductase (MTHFR) gene 677C>T and 1298A>C polymorphisms are associated with differential apoptosis of leukemic B cells in vitro and disease progression in chronic lymphocytic leukemia.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MDM2 SNP309 is associated with poor outcome in B-cell chronic lymphocytic leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prognostic assessment of BCL2-938C>A polymorphism in chronic lymphocytic leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2A activity is induced during B-cell activation to promote immunoglobulin class switch recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Receptor editing and marginal zone B cell development are regulated by the helix-loop-helix protein, E2A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
B cells, E2A, and aging
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Restricted expression of E2A protein in primary human tissues correlates with proliferation and differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of the E2A basic helix-loop-helix protein in immunoglobulin heavy chain class switching
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E-proteins directly regulate expression of activation-induced deaminase in mature B cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High expression of AID and active class switch recombination might account for a more aggressive disease in unmutated CLL patients: link with an activated microenvironment in CLL disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2010.291
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/LEU.2010.291
1 reference
stated in
Europe PubMed Central
PubMed ID
21212793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21212793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
Dimensions Publication ID
1025592424
0 references
PubMed ID
21212793
1 reference
stated in
Europe PubMed Central
PubMed ID
21212793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21212793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
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