(Q83219069)

English

Oleate-mediated activation of phospholipase D and mammalian target of rapamycin (mTOR) regulates proliferation and rapamycin sensitivity of hepatocarcinoma cells

scientific article published on 15 January 2011

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21240477%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Oleate-mediated activation of phospholipase D and mammalian target of rapamycin (mTOR) regulates proliferation and rapamycin sensitivity of hepatocarcinoma cells (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21240477%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

based on heuristic

inferred from title

author name string

C Arous

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21240477%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

M Naïmi

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21240477%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

E Van Obberghen

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21240477%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

publication date

15 January 2011

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21240477%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21240477%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

54

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21240477%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21240477%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

954-964

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21240477%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

https://scigraph.springernature.com/pub.10.1007/s00125-010-2032-1

0 references

Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil red O.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapamycin-insensitive regulation of 4e-BP1 in regenerating rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular signal-regulated kinase induces cyclin D1 and Cdk-2 expression and phosphorylation of retinoblastoma in hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ras pathway activation in hepatocellular carcinoma and anti-tumoral effect of combined sorafenib and rapamycin in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective activation of phospholipase D2 by unsaturated fatty acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High intensity ERK signal mediates hepatocyte growth factor-induced proliferation inhibition of the human hepatocellular carcinoma cell line HepG2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unsaturated fatty acids promote hepatoma proliferation and progression through downregulation of the tumor suppressor PTEN.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Obesity and hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of mammalian target of rapamycin complex 1 and insulin resistance induced by palmitate in hepatocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of signaling pathways in the development and treatment of hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single amino-acid changes that confer constitutive activation of mTOR are discovered in human cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of hepatic adipogenesis is associated with impaired liver regeneration in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse liver tumorigenesis: models, mechanisms, and relevance to human disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phospholipase D2-derived phosphatidic acid binds to and activates ribosomal p70 S6 kinase independently of mTOR

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phospholipase D-mTOR requirement for the Warburg effect in human cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidic acid signaling to mTOR: signals for the survival of human cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abrogation of de novo lipogenesis by stearoyl-CoA desaturase 1 inhibition interferes with oncogenic signaling and blocks prostate cancer progression in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclins and cyclin-dependent kinases: comparative study of hepatocellular carcinoma versus cirrhosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidic acid-mediated mitogenic activation of mTOR signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TOR signaling in growth and metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An emerging role of mTOR in lipid biosynthesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor- or rictor-independent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonalcoholic fatty liver disease: pathology and pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mRNA 5' cap-binding protein eIF4E and control of cell growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatocyte growth factor has potent anti-proliferative activity in various tumor cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of myotubularin by an adenoviral vector demonstrates its function as a phosphatidylinositol 3-phosphate [PtdIns(3)P] phosphatase in muscle cell lines: involvement of PtdIns(3)P in insulin-stimulated glucose transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell biology. A metabolic push to proliferate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21240477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q83219069&oldid=1513037576"