(Q83256315)

English

Evaluation of a HER2-targeting affibody molecule combining an N-terminal HEHEHE-tag with a GGGC chelator for 99mTc-labelling at the C terminus

scientific article published on 17 January 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249974%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Evaluation of a HER2-targeting affibody molecule combining an N-terminal HEHEHE-tag with a GGGC chelator for 99mTc-labelling at the C terminus (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249974%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249974%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Vladimir Tolmachev

9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249974%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

author name string

Hanna Lindberg

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249974%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Camilla Hofström

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249974%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Mohamed Altai

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249974%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Hadis Honorvar

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249974%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Helena Wållberg

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249974%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Stefan Ståhl

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249974%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Torbjörn Gräslund

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249974%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

publication date

17 January 2012

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249974%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249974%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

33

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249974%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249974%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

641-651

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22249974%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

https://scigraph.springernature.com/pub.10.1007/s13277-011-0305-z

0 references

Selection and characterization of Affibody ligands to the transcription factor c-Jun

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting of HER2-expressing tumors with a site-specifically 99mTc-labeled recombinant affibody molecule, ZHER2:2395, with C-terminally engineered cysteine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kit formulation for 99mTc-labeling of recombinant anti-HER2 Affibody molecules with a C-terminally engineered cysteine

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor imaging using a picomolar affinity HER2 binding affibody molecule

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(186)Re-maSGS-Z (HER2:342), a potential Affibody conjugate for systemic therapy of HER2-expressing tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Order of amino acids in C-terminal cysteine-containing peptide-based chelators influences cellular processing and biodistribution of 99mTc-labeled recombinant Affibody molecules.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of lysine-containing mercaptoacetyl-based chelators on the biodistribution of 99mTc-labeled anti-HER2 Affibody molecules.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radionuclide molecular imaging using Affibody molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Affinity recovery of eight HER2-binding affibody variants using an anti-idiotypic affibody molecule as capture ligand.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HEHEHE-tagged affibody molecule may be purified by IMAC, is conveniently labeled with [⁹⁹(m)Tc(CO)₃](+), and shows improved biodistribution with reduced hepatic radioactivity accumulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Imaging of HER-2 overexpression in tumors for guiding therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HER2 expression in breast cancer primary tumours and corresponding metastases. Original data and literature review

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design, synthesis and biological evaluation of a multifunctional HER2-specific Affibody molecule for molecular imaging.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of maleimide derivative of DOTA for site-specific labeling of recombinant affibody molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Affibody molecules: engineered proteins for therapeutic, diagnostic and biotechnological applications.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[(177)Lu]pertuzumab: experimental studies on targeting of HER-2 positive tumour cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HER-2--a possible target for therapy of metastatic urinary bladder carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of a HEHEHE purification tag instead of a hexahistidine tag improves biodistribution of affibody molecules site-specifically labeled with (99m)Tc, (111)In, and (125)I.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Untangling the ErbB signalling network

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative in vivo evaluation of technetium and iodine labels on an anti-HER2 affibody for single-photon imaging of HER2 expression in tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular design and optimization of 99mTc-labeled recombinant affibody molecules improves their biodistribution and imaging properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human epidermal growth factor receptor-2-positive breast cancer: Current management of early, advanced, and recurrent disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(99m)Tc-maEEE-Z(HER2:342), an Affibody molecule-based tracer for the detection of HER2 expression in malignant tumors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

99mTc-chelator engineering to improve tumour targeting properties of a HER2-specific Affibody molecule.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development and preclinical characterisation of 99mTc-labelled Affibody molecules with reduced renal uptake.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Imaging of HER2-expressing tumours using a synthetic Affibody molecule containing the 99mTc-chelating mercaptoacetyl-glycyl-glycyl-glycyl (MAG3) sequence.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trastuzumab: a new treatment option for HER2-positive metastatic gastric and gastroesophageal junction cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of the oncogene c-erbB-2 (HER2/neu) in ovarian cancer: a new prognostic factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiolabelled receptor-tyrosine-kinase targeting drugs for patient stratification and monitoring of therapy response: prospects and pitfalls.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Slow internalization of anti-HER2 synthetic affibody monomer 111In-DOTA-ZHER2:342-pep2: implications for development of labeled tracers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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