(Q83412055)

English

Blockade of IL-6 signaling exacerbates liver injury and suppresses antiapoptotic gene expression in methionine choline-deficient diet-fed db/db mice

scientific article published on 14 February 2011

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scholarly article

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22 January 2020

Blockade of IL-6 signaling exacerbates liver injury and suppresses antiapoptotic gene expression in methionine choline-deficient diet-fed db/db mice (English)

1 reference

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22 January 2020

author name string

Kanji Yamaguchi

1

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22 January 2020

Yoshito Itoh

2

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22 January 2020

Chihiro Yokomizo

3

1 reference

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22 January 2020

Takeshi Nishimura

4

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22 January 2020

Toshihisa Niimi

5

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22 January 2020

Atsushi Umemura

6

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22 January 2020

Hideki Fujii

7

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22 January 2020

Takeshi Okanoue

8

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22 January 2020

Toshikazu Yoshikawa

9

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22 January 2020

publication date

14 February 2011

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22 January 2020

Laboratory Investigation

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22 January 2020

91

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22 January 2020

4

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22 January 2020

609-618

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22 January 2020

https://scigraph.springernature.com/pub.10.1038/labinvest.2011.2

0 references

Gene expression patterns in hepatic tissue and visceral adipose tissue of patients with non-alcoholic fatty liver disease

1 reference

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7 January 2021

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Adipokines and cytokines in non-alcoholic fatty liver disease

1 reference

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7 January 2021

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Increased hepatic and circulating interleukin-6 levels in human nonalcoholic steatohepatitis

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.2

7 January 2021

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Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.2

7 January 2021

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ICAM-1 triggers liver regeneration through leukocyte recruitment and Kupffer cell-dependent release of TNF-alpha/IL-6 in mice

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.2

7 January 2021

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gp130 receptor ligands as potential therapeutic targets for obesity

1 reference

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Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo

1 reference

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7 January 2021

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The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.2

7 January 2021

based on heuristic

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Interleukin-6 protects against Fas-mediated death by establishing a critical level of anti-apoptotic hepatic proteins FLIP, Bcl-2, and Bcl-xL.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.2

7 January 2021

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In vitro interleukin-6 treatment prevents mortality associated with fatty liver transplants in rats

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.2

7 January 2021

based on heuristic

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Interleukin-6 inhibits oxidative injury and necrosis after extreme liver resection.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.2

7 January 2021

based on heuristic

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Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

1 reference

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7 January 2021

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Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.2

7 January 2021

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Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.2

7 January 2021

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Hepatic free fatty acids accumulate in experimental steatohepatitis: role of adaptive pathways

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.2

7 January 2021

based on heuristic

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Blockade of interleukin-6 signaling enhances hepatic steatosis but improves liver injury in methionine choline-deficient diet-fed mice

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.2

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of anti-mouse interleukin-6 receptor antibody

1 reference

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7 January 2021

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Interleukin-6 receptor-mediated activation of signal transducer and activator of transcription-3 (STAT3) promotes choroidal neovascularization

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.2

7 January 2021

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Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.2

7 January 2021

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.2

7 January 2021

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Analyzing real-time PCR data by the comparative C(T) method

1 reference

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7 January 2021

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Blockade of interleukin-6 receptor suppresses reactive astrogliosis and ameliorates functional recovery in experimental spinal cord injury

1 reference

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7 January 2021

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Anti-IL-6 receptor antibody increases blood IL-6 level via the blockade of IL-6 clearance, but not via the induction of IL-6 production

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.2

7 January 2021

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Steatohepatitis: a tale of two "hits"?

1 reference

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7 January 2021

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Combined interleukin 6 and soluble interleukin 6 receptor accelerates murine liver regeneration

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.2

7 January 2021

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Paradoxical effects of short- and long-term interleukin-6 exposure on liver injury and repair.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.2

7 January 2021

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Short-term infusion of interleukin-6 does not induce insulin resistance in vivo or impair insulin signalling in rats

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.2

7 January 2021

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Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes.

1 reference

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7 January 2021

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Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse

1 reference

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STAT3 signalling is required for leptin regulation of energy balance but not reproduction

1 reference

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7 January 2021

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Activation of downstream signals by the long form of the leptin receptor

1 reference

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7 January 2021

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Lack of interleukin-6/glycoprotein 130/signal transducers and activators of transcription-3 signaling in hepatocytes predisposes to liver steatosis and injury in mice

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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