(Q83821273)

English

Protein structural conformation and not second virial coefficient relates to long-term irreversible aggregation of a monoclonal antibody and ovalbumin in solution

scientific article published on 25 May 2006

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16715374%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Protein structural conformation and not second virial coefficient relates to long-term irreversible aggregation of a monoclonal antibody and ovalbumin in solution (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16715374%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

monoclonal antibody

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author name string

Harminder Bajaj

1

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28 January 2020

Vikas K Sharma

2

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28 January 2020

Advait Badkar

3

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28 January 2020

David Zeng

4

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28 January 2020

Sandeep Nema

5

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28 January 2020

Devendra S Kalonia

6

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28 January 2020

publication date

25 May 2006

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28 January 2020

Pharmaceutical Research

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28 January 2020

23

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28 January 2020

6

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28 January 2020

1382-1394

1 reference

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28 January 2020

Mutations and off-pathway aggregation of proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-native intermediate conformational states of human growth hormone in the presence of organic solvents

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The likelihood of aggregation during protein renaturation can be assessed using the second virial coefficient

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of conformational stability and colloidal stability in the aggregation of recombinant human granulocyte colony‐stimulating factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Irreversible aggregation of recombinant bovine granulocyte-colony stimulating factor (bG-CSF) and implications for predicting protein shelf life

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The thermal stability of immunoglobulin: unfolding and aggregation of a multi-domain protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temperature- and pH-induced multiple partially unfolded states of recombinant human interferon-alpha2a: possible implications in protein stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular origins of osmotic second virial coefficients of proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circumnavigating misfolding traps in the energy landscape through protein engineering: suppression of molten globule and aggregation in carbonic anhydrase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aggregation of granulocyte colony stimulating factor under physiological conditions: characterization and thermodynamic inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The development of stable protein formulations: a close look at protein aggregation, deamidation, and oxidation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reshaping the folding energy landscape by chloride salt: impact on molten-globule formation and aggregation behavior of carbonic anhydrase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrogen exchange in a large 29 kD protein and characterization of molten globule aggregation by NMR.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural characterization of bovine granulocyte colony stimulating factor: effect of temperature and pH.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of aggregate formation and carbohydrate excipient stabilization of lyophilized humanized monoclonal antibody formulations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microcalorimetric studies of the effects on the interactions of human recombinant interferon-alpha2a

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A transient expansion of the native state precedes aggregation of recombinant human interferon-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compact intermediate states in protein folding.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteins as random coils. IV. Osmotic pressures, second virial coefficients, and unperturbed dimensions in 6M guanidine hydrochloride

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of an associated equilibrium folding intermediate of bovine growth hormone

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is stability prediction possible for protein drugs? Denaturation kinetics of beta-galactosidase in solution.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[6] Second virial coefficient as predictor in protein crystal growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of intermediates on aggregation of native bovine serum albumin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factors influencing the immunogenicity of therapeutic proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of second virial coefficient of proteins using a dual-detector cell for simultaneous measurement of scattered light intensity and concentration in SEC-HPLC.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Infrared Spectroscopic Studies of Lyophilization‐ and Temperature‐Induced Protein Aggregation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of lysozyme in guanidinium chloride solutions from static and dynamic light-scattering measurements

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a partially folded intermediate in alpha-synuclein fibril formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molten globule and protein folding

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aggregation of granulocyte-colony stimulating factor in vitro involves a conformationally altered monomeric state

1 reference

https://pubmed.ncbi.nlm.nih.gov/16715374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11095-006-0018-Y

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16715374%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16715374%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

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