(Q84143317)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19565336%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

editorial

0 references

title

Challenges of fragment screening (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19565336%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

author name string

Diane Joseph-McCarthy

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19565336%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

publication date

30 June 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19565336%20AND%20SRC:MED&resulttype=core&format=json

Journal of Computer - Aided Molecular Design

1 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19565336%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19565336%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19565336%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

page(s)

449-451

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19565336%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s10822-009-9293-0

1 February 2020

exact match

0 references

cites work

Automated generation of MCSS-derived pharmacophoric DOCK site points for searching multiconformation databases

1 reference

12 December 2020

Computer-based de novo design of drug-like molecules

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12 December 2020

HOOK: a program for finding novel molecular architectures that satisfy the chemical and steric requirements of a macromolecule binding site

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12 December 2020

Computational fragment-based approach at PDB scale by protein local similarity

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12 December 2020

Functionality maps of binding sites: a multiple copy simultaneous search method

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12 December 2020

Discovery of a novel warhead against beta-secretase through fragment-based lead generation

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Fragment-based lead discovery using X-ray crystallography.

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12 December 2020

Pharmacophore-based molecular docking to account for ligand flexibility

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12 December 2020

CAVEAT: a program to facilitate the design of organic molecules

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12 December 2020

On the use of LUDI to search the Fine Chemicals Directory for ligands of proteins of known three-dimensional structure

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12 December 2020

Developing a dynamic pharmacophore model for HIV-1 integrase.

1 reference

12 December 2020

SuperStar: a knowledge-based approach for identifying interaction sites in proteins.

1 reference

12 December 2020

CONFIRM: connecting fragments found in receptor molecules

1 reference

12 December 2020

Fragment-based discovery of the pyrazol-4-yl urea (AT9283), a multitargeted kinase inhibitor with potent aurora kinase activity

1 reference

12 December 2020

Molecular docking and ligand specificity in fragment-based inhibitor discovery

1 reference

12 December 2020

Application of fragment screening and fragment linking to the discovery of novel thrombin inhibitors.

1 reference

12 December 2020

A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design

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12 December 2020

LUDI: rule-based automatic design of new substituents for enzyme inhibitor leads

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12 December 2020

A computational procedure for determining energetically favorable binding sites on biologically important macromolecules

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12 December 2020

Druggability indices for protein targets derived from NMR-based screening data

1 reference

12 December 2020

Ligand design by a combinatorial approach based on modeling and experiment: application to HLA-DR4.

1 reference

12 December 2020

Application of fragment-based lead generation to the discovery of novel, cyclic amidine beta-secretase inhibitors with nanomolar potency, cellular activity, and high ligand efficiency

1 reference

12 December 2020

Recore: a fast and versatile method for scaffold hopping based on small molecule crystal structure conformations

1 reference

12 December 2020

An integrated approach to fragment-based lead generation: philosophy, strategy and case studies from AstraZeneca's drug discovery programmes.

1 reference

12 December 2020

10.1007/S10822-009-9293-0

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19565336%20AND%20SRC:MED&resulttype=core&format=json

journals/jcamd/Joseph-McCarthy09

1 February 2020

DBLP publication ID

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference