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Regulatory role for the profilaggrin N-terminal domain in epidermal homeostasis
scientific article published on 24 May 2012
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22622429
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22622429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
title
Regulatory role for the profilaggrin N-terminal domain in epidermal homeostasis
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22622429
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22622429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
author name string
Sirpa Aho
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22622429
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22622429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
Clive R Harding
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22622429
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22622429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
Jian-Ming Lee
series ordinal
3
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Europe PubMed Central
PubMed publication ID
22622429
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22622429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
Helen Meldrum
series ordinal
4
1 reference
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Europe PubMed Central
PubMed publication ID
22622429
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22622429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
Carol A Bosko
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22622429
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22622429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
language of work or name
English
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publication date
24 May 2012
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22622429
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22622429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
published in
Journal of Investigative Dermatology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22622429
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22622429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
volume
132
1 reference
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Europe PubMed Central
PubMed publication ID
22622429
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22622429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
issue
10
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Europe PubMed Central
PubMed publication ID
22622429
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22622429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
page(s)
2376-2385
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22622429
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22622429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
exact match
https://scigraph.springernature.com/pub.10.1038/jid.2012.174
0 references
cites work
S100 protein subcellular localization during epidermal differentiation and psoriasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
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inferred from DOI database lookup
Intragenic copy number variation within filaggrin contributes to the risk of atopic dermatitis with a dose-dependent effect
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
One remarkable molecule: filaggrin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chalone control mechanisms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
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inferred from DOI database lookup
Endoplasmic reticulum Ca2+ depletion activates XBP1 and controls terminal differentiation in keratinocytes and epidermis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-14 protects against epidermal UVB photodamage and water loss
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chalone inhibition of cellular proliferation.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proliferation-dependent effect of skin extracts (chalone) on mouse epidermal cell flux at the G1S, S-G2 and G2-M transitions
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FJID.2012.174
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7 January 2021
based on heuristic
inferred from DOI database lookup
A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
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7 January 2021
based on heuristic
inferred from DOI database lookup
Lentivirus-mediated gene transfer to human epidermis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Filaggrin repeat number polymorphism is associated with a dry skin phenotype
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss-of-Function Variants of the Filaggrin Gene Are Not Major Susceptibility Factors for Psoriasis Vulgaris or Psoriatic Arthritis in German Patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epidermal turnover time
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The epidermal barrier function is dependent on the serine protease CAP1/Prss8
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of proteolytically processed filaggrin caused by epidermal deletion of Matriptase/MT-SP1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
S100 proteins in mouse and man: from evolution to function and pathology (including an update of the nomenclature)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Profilaggrin is a major epidermal calcium-binding protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Knockdown of filaggrin impairs diffusion barrier function and increases UV sensitivity in a human skin model
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Decreased profilaggrin expression in ichthyosis vulgaris is a result of selectively impaired posttranscriptional control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Onset of re-epithelialization after skin injury correlates with a reorganization of keratin filaments in wound edge keratinocytes: defining a potential role for keratin 16
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional analysis of the profilaggrin N-terminal peptide: identification of domains that regulate nuclear and cytoplasmic distribution
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
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inferred from DOI database lookup
Proprotein convertase expression and localization in epidermis: evidence for multiple roles and substrates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of two distinct calcium-binding sites in the amino-terminus of human profilaggrin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of normal profilaggrin and filaggrin in flaky tail (ft/ft) mice: an animal model for the filaggrin-deficient skin disease ichthyosis vulgaris
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for specific proteolytic cleavage of the N-terminal domain of human profilaggrin during epidermal differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulated expression of human filaggrin in keratinocytes results in cytoskeletal disruption, loss of cell-cell adhesion, and cell cycle arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The epidermal G1-chalone: an endogenous tissue-specific inhibitor of epidermal cell proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevalent and Rare Mutations in the Gene Encoding Filaggrin Cause Ichthyosis Vulgaris and Predispose Individuals to Atopic Dermatitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alterations in the metabolism of filaggrin in the skin after chemical- and ultraviolet-induced erythema
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of human hornerin and its expression in regenerating and psoriatic skin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle specificity and reversibility of the inhibitory effect of epidermal G1-chalone on DNA synthesis in partially synchronized RTE-2 keratinocytes in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cutaneous barrier perturbation stimulates cytokine production in the epidermis of mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular identification and expression analysis of filaggrin-2, a member of the S100 fused-type protein family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of the profilaggrin N-terminal domain with loricrin in human cultured keratinocytes and epidermis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of mouse profilaggrin: evidence for nuclear engulfment and translocation of the profilaggrin B-domain during epidermal differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Filaggrin null alleles are not associated with psoriasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
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inferred from DOI database lookup
Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FJID.2012.174
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/JID.2012.174
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22622429
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22622429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
Dimensions Publication ID
1004823828
0 references
PubMed publication ID
22622429
1 reference
stated in
Europe PubMed Central
PubMed publication ID
22622429
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22622429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
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