(Q84325850)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21660514%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

title

Homology modeling, docking and structure-based pharmacophore of inhibitors of DNA methyltransferase (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21660514%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

author name string

Jakyung Yoo

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21660514%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

José L Medina-Franco

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21660514%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

publication date

10 June 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21660514%20AND%20SRC:MED&resulttype=core&format=json

Journal of Computer - Aided Molecular Design

4 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21660514%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

volume

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21660514%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21660514%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

page(s)

555-567

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21660514%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s10822-011-9441-1

4 February 2020

exact match

0 references

1 reference

12 December 2020

Curcumin is a potent DNA hypomethylation agent

1 reference

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DNA demethylating antineoplastic strategies: a comparative point of view

1 reference

12 December 2020

Green tea and its polyphenolic catechins: medicinal uses in cancer and noncancer applications

1 reference

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Plasma pharmacokinetics, oral bioavailability, and interspecies scaling of the DNA methyltransferase inhibitor, zebularine

1 reference

12 December 2020

Antitumor, anti-invasion, and antimetastatic effects of curcumin

1 reference

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Cellular differentiation, cytidine analogs and DNA methylation

1 reference

12 December 2020

DNA methyltransferase inhibitors: old and new drugs for an epigenetic cancer therapy

1 reference

12 December 2020

DNA methylation and human disease

1 reference

12 December 2020

Advances in the computational development of DNA methyltransferase inhibitors

1 reference

12 December 2020

Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines.

1 reference

12 December 2020

Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2

1 reference

12 December 2020

Modulation of DNA methylation by a sesquiterpene lactone parthenolide

1 reference

12 December 2020

Novel method for generating structure-based pharmacophores using energetic analysis

1 reference

12 December 2020

5-Azacytidine, a new, highly effective cancerostatic

1 reference

12 December 2020

Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases

1 reference

12 December 2020

Phase I dose escalation trial of feverfew with standardized doses of parthenolide in patients with cancer.

1 reference

12 December 2020

Design, synthesis, inhibitory activity, and binding mode study of novel DNA methyltransferase 1 inhibitors

1 reference

12 December 2020

The sesquiterpene lactone parthenolide induces selective apoptosis of B-chronic lymphocytic leukemia cells in vitro

1 reference

12 December 2020

Worms gang up on bacteria

1 reference

12 December 2020

DNA containing 4'-thio-2'-deoxycytidine inhibits methylation by HhaI methyltransferase

1 reference

12 December 2020

Zebularine inhibits human acute myeloid leukemia cell growth in vitro in association with p15INK4B demethylation and reexpression.

1 reference

12 December 2020

Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells.

1 reference

12 December 2020

Hydralazine target: from blood vessels to the epigenome

1 reference

12 December 2020

Hydralazine is a powerful inhibitor of peroxynitrite formation as a possible explanation for its beneficial effects on prognosis in patients with congestive heart failure

1 reference

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Phase II trial of curcumin in patients with advanced pancreatic cancer

1 reference

12 December 2020

DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B.

1 reference

12 December 2020

Phase I dose escalation trial of docetaxel plus curcumin in patients with advanced and metastatic breast cancer

1 reference

12 December 2020

Concentrations of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine (FdCyd) and its cytotoxic metabolites in plasma of patients treated with FdCyd and tetrahydrouridine (THU).

1 reference

12 December 2020

FDA drug approval summary: azacitidine (5-azacytidine, Vidaza) for injectable suspension

1 reference

12 December 2020

The prince and the pauper. A tale of anticancer targeted agents

1 reference

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Human DNMT2 methylates tRNA(Asp) molecules using a DNA methyltransferase-like catalytic mechanism

1 reference

12 December 2020

Mahanine reverses an epigenetically silenced tumor suppressor gene RASSF1A in human prostate cancer cells

1 reference

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Comparison of Composer and ORCHESTRAR.

1 reference

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Mahanine inhibits growth and induces apoptosis in prostate cancer cells through the deactivation of Akt and activation of caspases

1 reference

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Epigenetics, oxidative stress, and Alzheimer disease

1 reference

12 December 2020

Establishment and functional validation of a structural homology model for human DNA methyltransferase 1.

1 reference

12 December 2020

Natural products as DNA methyltransferase inhibitors: a computer-aided discovery approach

1 reference

12 December 2020

Pharmacokinetics, metabolism, and oral bioavailability of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine in mice

1 reference

12 December 2020

A phase I study of hydralazine to demethylate and reactivate the expression of tumor suppressor genes

1 reference

12 December 2020

Energetic analysis of fragment docking and application to structure-based pharmacophore hypothesis generation

1 reference

12 December 2020

Role of cysteine residues of p65/NF-kappaB on the inhibition by the sesquiterpene lactone parthenolide and N-ethyl maleimide, and on its transactivating potential

1 reference

12 December 2020

Biochemistry and biology of mammalian DNA methyltransferases

1 reference

12 December 2020

Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study

1 reference

12 December 2020

Preferential response of cancer cells to zebularine.

1 reference

12 December 2020

Metabolic activation of zebularine, a novel DNA methylation inhibitor, in human bladder carcinoma cells

1 reference

12 December 2020

Reactivation of tumor suppressor genes by the cardiovascular drugs hydralazine and procainamide and their potential use in cancer therapy

1 reference

12 December 2020

The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IkappaB kinase

1 reference

12 December 2020

Discovery of two novel, small-molecule inhibitors of DNA methylation

1 reference

12 December 2020

Epigenetic reactivation of tumor suppressor genes by a novel small-molecule inhibitor of human DNA methyltransferases.

1 reference

12 December 2020

Cortical DNA methylation maintains remote memory

1 reference

12 December 2020

EGCG inhibits growth and induces apoptosis in renal cell carcinoma through TFPI-2 overexpression.

1 reference

12 December 2020

Anticancer drug discovery targeting DNA hypermethylation

1 reference

12 December 2020

Synthesis and in vitro evaluation of biotinylated RG108: a high affinity compound for studying binding interactions with human DNA methyltransferases

1 reference

12 December 2020

Procainamide is a specific inhibitor of DNA methyltransferase 1.

1 reference

12 December 2020

Novel inhibitors of dengue virus methyltransferase: discovery by in vitro-driven virtual screening on a desktop computer grid

1 reference

12 December 2020

Zebularine: a candidate for epigenetic cancer therapy

1 reference

12 December 2020

Novel and selective DNA methyltransferase inhibitors: Docking-based virtual screening and experimental evaluation

1 reference

12 December 2020

Promoter demethylation of WIF-1 by epigallocatechin-3-gallate in lung cancer cells.

1 reference

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Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells

1 reference

12 December 2020

Recombinant human DNA (cytosine-5) methyltransferase. II. Steady-state kinetics reveal allosteric activation by methylated dna.

1 reference

12 December 2020

Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids

1 reference

12 December 2020

Role of estrogen receptor gene demethylation and DNA methyltransferase.DNA adduct formation in 5-aza-2'deoxycytidine-induced cytotoxicity in human breast cancer cells

1 reference

12 December 2020

A phase II study of epigenetic therapy with hydralazine and magnesium valproate to overcome chemotherapy resistance in refractory solid tumors.

1 reference

12 December 2020

Molecular modeling and molecular dynamics studies of hydralazine with human DNA methyltransferase 1.

1 reference

12 December 2020

Mammalian DNA methyltransferases: a structural perspective

1 reference

12 December 2020

Solving the Dnmt2 enigma.

1 reference

12 December 2020

The Universal Protein Resource (UniProt) in 2010

1 reference

12 December 2020

Zebularine: A Novel DNA Methylation Inhibitor that Forms a Covalent Complex with DNA Methyltransferases

1 reference

12 December 2020

Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors

1 reference

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Phase I study of decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura

1 reference

12 December 2020

Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases

1 reference

12 December 2020

The fundamental role of epigenetic events in cancer

1 reference

12 December 2020

10.1007/S10822-011-9441-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21660514%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

DBLP publication ID

journals/jcamd/YooM11

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference