(Q84372028)

English

A phase I study of DHP107, a mucoadhesive lipid form of oral paclitaxel, in patients with advanced solid tumors: crossover comparisons with intravenous paclitaxel

scientific article published on 14 June 2012

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695940%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

A phase I study of DHP107, a mucoadhesive lipid form of oral paclitaxel, in patients with advanced solid tumors: crossover comparisons with intravenous paclitaxel (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695940%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

based on heuristic

inferred from title

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695940%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

author name string

Yong Sang Hong

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695940%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Kyu-pyo Kim

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695940%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Hyeong-Seok Lim

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695940%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Min-Hee Ryu

5

1 reference

Europe PubMed Central

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5 February 2020

Jae-Lyun Lee

6

1 reference

Europe PubMed Central

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5 February 2020

Heung Moon Chang

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695940%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Yoon-Koo Kang

8

1 reference

Europe PubMed Central

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5 February 2020

Hyeyoun Kim

9

1 reference

Europe PubMed Central

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5 February 2020

Tae Won Kim

10

1 reference

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5 February 2020

publication date

14 June 2012

1 reference

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5 February 2020

Investigational New Drugs

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22695940%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

31

1 reference

Europe PubMed Central

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5 February 2020

3

1 reference

Europe PubMed Central

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5 February 2020

616-622

1 reference

Europe PubMed Central

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5 February 2020

https://scigraph.springernature.com/pub.10.1007/s10637-012-9841-7

0 references

Hypersensitivity reactions from taxol

1 reference

https://pubmed.ncbi.nlm.nih.gov/22695940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I and pharmacokinetic study of oral paclitaxel

1 reference

https://pubmed.ncbi.nlm.nih.gov/22695940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low-dose metronomic chemotherapy of paclitaxel synergizes with cetuximab to suppress human colon cancer xenografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/22695940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced absorption and tissue distribution of paclitaxel following oral administration of DHP 107, a novel mucoadhesive lipid dosage form

1 reference

https://pubmed.ncbi.nlm.nih.gov/22695940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase III, double-blind, randomized study comparing lapatinib plus paclitaxel with placebo plus paclitaxel as first-line treatment for metastatic breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22695940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective biotransformation of taxol to 6 alpha-hydroxytaxol by human cytochrome P450 2C8

1 reference

https://pubmed.ncbi.nlm.nih.gov/22695940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase I and pharmacokinetic study of bi-daily dosing of oral paclitaxel in combination with cyclosporin A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22695940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and tissue distribution of DHP107, an oral paclitaxel formulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22695940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Entrapment by Cremophor EL decreases the absorption of paclitaxel from the gut.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22695940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neoadjuvant chemotherapy or primary surgery in stage IIIC or IV ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22695940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral paclitaxel and concurrent cyclosporin A: targeting clinically relevant systemic exposure to paclitaxel

1 reference

https://pubmed.ncbi.nlm.nih.gov/22695940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pharmacokinetic and safety study of a novel polymeric paclitaxel formulation for oral application

1 reference

https://pubmed.ncbi.nlm.nih.gov/22695940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation, purification, and biological activity of mono- and dihydroxylated paclitaxel metabolites from human feces

1 reference

https://pubmed.ncbi.nlm.nih.gov/22695940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase II study of paclitaxel and capecitabine as a first-line combination chemotherapy for advanced gastric cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22695940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Randomized Phase III Trial of Weekly Compared With Every-3-Weeks Paclitaxel for Metastatic Breast Cancer, With Trastuzumab for all HER-2 Overexpressors and Random Assignment to Trastuzumab or Not in HER-2 Nonoverexpressors: Final Results of Cancer an

1 reference

https://pubmed.ncbi.nlm.nih.gov/22695940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL

1 reference

https://pubmed.ncbi.nlm.nih.gov/22695940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cremophor EL, solvent for paclitaxel, and toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22695940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel paclitaxel formulations for oral application: a phase I pharmacokinetic study in patients with solid tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/22695940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-administration of GF120918 significantly increases the systemic exposure to oral paclitaxel in cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22695940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The anti-angiogenic basis of metronomic chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22695940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral bioavailability of a novel paclitaxel formulation (Genetaxyl) administered with cyclosporin A in cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22695940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22695940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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