(Q84389022)

English

Reversal of type 1 diabetes by a new MHC II-peptide chimera: "Single-epitope-mediated suppression" to stabilize a polyclonal autoimmune T-cell process

scientific article published on 01 August 2010

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scholarly article

1 reference

Europe PubMed Central

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5 February 2020

Reversal of type 1 diabetes by a new MHC II-peptide chimera: "Single-epitope-mediated suppression" to stabilize a polyclonal autoimmune T-cell process (English)

1 reference

Europe PubMed Central

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5 February 2020

type-1 diabetes

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author name string

Marvin Lin

1

1 reference

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5 February 2020

Cristina Stoica-Nazarov

2

1 reference

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5 February 2020

Jacqueline Surls

3

1 reference

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5 February 2020

Margaret Kehl

4

1 reference

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5 February 2020

Constantin Bona

5

1 reference

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5 February 2020

Cara Olsen

6

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5 February 2020

Teodor D Brumeanu

7

1 reference

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5 February 2020

Sofia Casares

8

1 reference

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5 February 2020

publication date

1 August 2010

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5 February 2020

European Journal of Immunology

1 reference

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5 February 2020

40

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5 February 2020

8

1 reference

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5 February 2020

2277-2288

1 reference

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5 February 2020

HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of MHC class II molecules in susceptibility to type I diabetes: identification of peptide epitopes and characterization of the T cell repertoire

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Type 1 diabetes: new perspectives on disease pathogenesis and treatment

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

T-cell compartments of prediabetic NOD mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Autoreactivity of T cells from nonobese diabetic mice: an I-Ag7-dependent reaction

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Genes and cellular requirements for autoimmune diabetes susceptibility in nonobese diabetic mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic protection from the inflammatory disease type 1 diabetes in humans and animal models

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

A comprehensive guide to antibody and T-cell responses in type 1 diabetes.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparison of cytokine ELISpot assay formats for the detection of islet antigen autoreactive T cells. Report of the third immunology of diabetes society T-cell workshop

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Detection of glutamic acid decarboxylase-activated T cells with I-Ag7 tetramers

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Detection of GAD65-specific T-cells by major histocompatibility complex class II tetramers in type 1 diabetic patients and at-risk subjects

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Soluble, dimeric HLA DR4-peptide chimeras: an approach for detection and immunoregulation of human type-1 diabetes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

On the pathogenicity of autoantigen-specific T-cell receptors

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

CD4(+) T cells from glutamic acid decarboxylase (GAD)65-specific T cell receptor transgenic mice are not diabetogenic and can delay diabetes transfer

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Prevention of type I diabetes transfer by glutamic acid decarboxylase 65 peptide 206-220-specific T cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Glutamic acid decarboxylase-specific CD4+ regulatory T cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Presence of diabetes-inhibiting, glutamic acid decarboxylase-specific, IL-10-dependent, regulatory T cells in naive nonobese diabetic mice.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

GAD-reactive CD4+ Th1 cells induce diabetes in NOD/SCID mice.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Detection of autoreactive T cells in type 1 diabetes using coded autoantigens and an immunoglobulin-free cytokine ELISPOT assay: report from the fourth immunology of diabetes society T cell workshop

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

CD8+ T lymphocytes specific for glutamic acid decarboxylase 90-98 epitope mediate diabetes in NOD SCID mouse.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

MHC class I-restricted determinants on the glutamic acid decarboxylase 65 molecule induce spontaneous CTL activity

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for a primary islet autoantigen (preproinsulin 1) for insulitis and diabetes in the nonobese diabetic mouse

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

The road not taken: a path to curing type 1 diabetes?

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Murine antithymocyte globulin therapy alters disease progression in NOD mice by a time-dependent induction of immunoregulation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

A comprehensive review of interventions in the NOD mouse and implications for translation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of systemic immunosuppression on islet engraftment and function into a subcutaneous biocompatible device

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Engineering and characterization of a murine MHC class II-immunoglobulin chimera expressing an immunodominant CD4 T viral epitope

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Enzymatically mediated engineering of multivalent MHC class II-peptide chimeras

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Down-regulation of diabetogenic CD4+ T cells by a soluble dimeric peptide-MHC class II chimera

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

A peptide-major histocompatibility complex II chimera favors survival of pancreatic beta-islets grafted in type 1 diabetic mice.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Efficacy of clonal deletion vs. anergy of self-reactive CD4 T-cells for the prevention and reversal of autoimmune diabetes.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Antigen-specific downregulation of T cells by doxorubicin delivered through a recombinant MHC II--peptide chimera

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Peptide-MHC class II dimers as therapeutics to modulate antigen-specific T cell responses in autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of ongoing T cell-mediated autoimmunity by peptide-MHC class II dimer vaccination

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Report from the 1st International NOD Mouse T-Cell Workshop and the follow-up mini-workshop

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

The type and frequency of immunoregulatory CD4+ T-cells govern the efficacy of antigen-specific immunotherapy in nonobese diabetic mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Antigen-specific signaling by a soluble, dimeric peptide/major histocompatibility complex class II/Fc chimera leading to T helper cell type 2 differentiation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunokinetics of autoreactive CD4 T cells in blood: a reporter for the "hit-and-run" autoimmune attack on pancreas and diabetes progression.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Systemic overexpression of IL-10 induces CD4+CD25+ cell populations in vivo and ameliorates type 1 diabetes in nonobese diabetic mice in a dose-dependent fashion

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

IL-10 and TGF-beta induce alloreactive CD4+CD25- T cells to acquire regulatory cell function

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical application of regulatory T cells for treatment of type 1 diabetes and transplantation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of tolerance in type 1 diabetes via both CD4+CD25+ T regulatory cells and T regulatory type 1 cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

The characterization and role of regulatory T cells in immune reactions

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

A mathematical model for the determination of total area under glucose tolerance and other metabolic curves

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200940094

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/EJI.200940094

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20540111%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20540111%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

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