(Q84424071)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21697885%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

Proteolytic activation cascade of the Netherton syndrome-defective protein, LEKTI, in the epidermis: implications for skin homeostasis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21697885%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21697885%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

author name string

Paola Fortugno

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21697885%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Chantal Paolini

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21697885%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Chiara Pazzagli

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21697885%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

May El Hachem

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21697885%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Marina D'Alessio

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21697885%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Giovanna Zambruno

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21697885%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

language of work or name

English

0 references

publication date

23 June 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21697885%20AND%20SRC:MED&resulttype=core&format=json

Journal of Investigative Dermatology

5 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21697885%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

volume

131

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21697885%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21697885%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

page(s)

2223-2232

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21697885%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/jid.2011.174

5 February 2020

exact match

0 references

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

LEKTI proteolytic processing in human primary keratinocytes, tissue distribution and defective expression in Netherton syndrome

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

A potential role for multiple tissue kallikrein serine proteases in epidermal desquamation

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Purification, molecular cloning, and expression of a human stratum corneum trypsin-like serine protease with possible function in desquamation

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

SPINK9: a selective, skin-specific Kazal-type serine protease inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Par2 inactivation inhibits early production of TSLP, but not cutaneous inflammation, in Netherton syndrome adult mouse model.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Degradation of corneodesmosome proteins by two serine proteases of the kallikrein family, SCTE/KLK5/hK5 and SCCE/KLK7/hK7

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Mutations in SPINK5, encoding a serine protease inhibitor, cause Netherton syndrome

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

LEKTI fragments specifically inhibit KLK5, KLK7, and KLK14 and control desquamation through a pH-dependent interaction

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Corneodesmosomal cadherins are preferential targets of stratum corneum trypsin- and chymotrypsin-like hyperactivity in Netherton syndrome

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Ex-vivo gene therapy restores LEKTI activity and corrects the architecture of Netherton syndrome-derived skin grafts

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Prediction of proprotein convertase cleavage sites

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

hK5 and hK7, two serine proteinases abundant in human skin, are inhibited by LEKTI domain 6.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

DNA delivery for vaccination and therapeutics through the skin

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Lethal, neonatal ichthyosis with increased proteolytic processing of filaggrin in a mouse model of Netherton syndrome

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Consequences of C-terminal domains and N-terminal signal peptide deletions on LEKTI secretion, stability, and subcellular distribution

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Correlation between SPINK5 gene mutations and clinical manifestations in Netherton syndrome patients

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Quantification of human tissue kallikreins in the stratum corneum: dependence on age and gender

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Multiple tissue kallikrein mRNA and protein expression in normal skin and skin diseases

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Homologous proteins with different folds: the three-dimensional structures of domains 1 and 6 of the multiple Kazal-type inhibitor LEKTI

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

LEKTI, a novel 15-domain type of human serine proteinase inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Isolation of SPINK6 in human skin: selective inhibitor of kallikrein-related peptidases

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Identification of lympho-epithelial Kazal-type inhibitor 2 in human skin as a kallikrein-related peptidase 5-specific protease inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

A unique case of trichorrhexis nodosa; bamboo hairs

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

The emerging roles of serine protease cascades in the epidermis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Comèl-Netherton syndrome defined as primary immunodeficiency

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

rAAV2-mediated restoration of LEKTI in LEKTI-deficient cells from Netherton patients

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Netherton syndrome: successful use of topical tacrolimus and pimecrolimus in four siblings.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Matriptase initiates activation of epidermal pro-kallikrein and disease onset in a mouse model of Netherton syndrome

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Inhibition of human kallikreins 5 and 7 by the serine protease inhibitor lympho-epithelial Kazal-type inhibitor (LEKTI).

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

SPINK5, the defective gene in netherton syndrome, encodes multiple LEKTI isoforms derived from alternative pre-mRNA processing

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Large-scale identification of human genes implicated in epidermal barrier function

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021

Epidermal detachment, desmosomal dissociation, and destabilization of corneodesmosin in Spink5-/- mice

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.174

7 January 2021