(Q84460610)

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Exosomes from human lymphoblastoid B cells express enzymatically active CD38 that is associated with signaling complexes containing CD81, Hsc-70 and Lyn

scientific article published on 04 June 2010

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6 February 2020

Exosomes from human lymphoblastoid B cells express enzymatically active CD38 that is associated with signaling complexes containing CD81, Hsc-70 and Lyn (English)

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6 February 2020

Adriana Ariza-Veguillas

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author name string

Esther Zumaquero

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Pilar Muñoz

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Marién Cobo

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Gema Lucena

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Esther J Pavón

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Ana Martín

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Pilar Navarro

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Angelica García-Pérez

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publication date

4 June 2010

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Experimental Cell Research

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2692-2706

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6 February 2020

Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology

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Antigen-induced clustering of surface CD38 and recruitment of intracellular CD38 to the immunologic synapse

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Lipid raft-associated protein sorting in exosomes.

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Exosomes--vesicular carriers for intercellular communication

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Lipid rafts and signal transduction

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Rafts defined: a report on the Keystone Symposium on Lipid Rafts and Cell Function.

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Segregation of sphingolipids and sterols during formation of secretory vesicles at the trans-Golgi network

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TCR signal initiation machinery is pre-assembled and activated in a subset of membrane rafts

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Microvillar membrane microdomains exist at physiological temperature. Role of galectin-4 as lipid raft stabilizer revealed by "superrafts".

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CD38 signaling in T cells is initiated within a subset of membrane rafts containing Lck and the CD3-zeta subunit of the T cell antigen receptor

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Recombinant anti-CD4 antibody 13B8.2 blocks membrane-proximal events by excluding the Zap70 molecule and downstream targets SLP-76, PLC gamma 1, and Vav-1 from the CD4-segregated Brij 98 detergent-resistant raft domains

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CD38/CD19: a lipid raft-dependent signaling complex in human B cells

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CD38 at the junction between prognostic marker and therapeutic target.

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CD38 is associated with lipid rafts and upon receptor stimulation leads to Akt/protein kinase B and Erk activation in the absence of the CD3-zeta immune receptor tyrosine-based activation motifs.

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Isolation and characterization of exosomes from cell culture supernatants and biological fluids

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TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex

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Heat shock protein 70 surface-positive tumor exosomes stimulate migratory and cytolytic activity of natural killer cells

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The CD3-gamma delta epsilon transducing module mediates CD38-induced protein-tyrosine kinase and mitogen-activated protein kinase activation in Jurkat T cells.

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Effects of cholesterol depletion by cyclodextrin on the sphingolipid microdomains of the plasma membrane

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CD38 is expressed as noncovalently associated homodimers on the surface of murine B lymphocytes

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Crystal structure of human CD38 extracellular domain

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rab5 controls early endosome fusion in vitro

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MHC class II/CD38/CD9: a lipid-raft-dependent signaling complex in human monocytes

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Critical role for cholesterol in Lyn-mediated tyrosine phosphorylation of FcepsilonRI and their association with detergent-resistant membranes

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CD38 and ZAP-70 are functionally linked and mark CLL cells with high migratory potential

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6 February 2020

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