(Q84550072)

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Influence of hepatocyte nuclear factor 4alpha (HNF4alpha) gene variants on the risk of type 2 diabetes: a meta-analysis in 49,577 individuals

scientific article published on 01 January 2010

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19748811%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

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Influence of hepatocyte nuclear factor 4alpha (HNF4alpha) gene variants on the risk of type 2 diabetes: a meta-analysis in 49,577 individuals (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19748811%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

type 2 diabetes

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based on heuristic

inferred from title

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based on heuristic

inferred from title

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19748811%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

author name string

Silvia Sookoian

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19748811%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Carolina Gemma

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19748811%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

publication date

1 January 2010

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19748811%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Molecular Genetics and Metabolism

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19748811%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

99

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19748811%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1

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7 February 2020

80-89

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19748811%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Type 2 diabetes: new genes, new understanding

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Gene prioritization based on biological plausibility over genome wide association studies renders new loci associated with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Activation of the insulin gene promoter through a direct effect of hepatocyte nuclear factor 4 alpha

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

The diabetic phenotype in HNF4A mutation carriers is moderated by the expression of HNF4A isoforms from the P1 promoter during fetal development.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

A susceptibility locus for early-onset non-insulin dependent (type 2) diabetes mellitus maps to chromosome 20q, proximal to the phosphoenolpyruvate carboxykinase gene

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Further evidence for a susceptibility locus for type 2 diabetes on chromosome 20q13.1-q13.2.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Common Variants in Maturity-Onset Diabetes of the Young Genes Contribute to Risk of Type 2 Diabetes in Finns

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Polymorphisms in both promoters of hepatocyte nuclear factor 4-alpha are associated with type 2 diabetes in the Amish

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Variation near the hepatocyte nuclear factor (HNF)-4alpha gene associates with type 2 diabetes in the Danish population

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Hepatocyte Nuclear Factor-4 P2 Promoter Haplotypes Are Associated With Type 2 Diabetes in the Japanese Population

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Common variants in maturity-onset diabetes of the young genes and future risk of type 2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Studies in 3,523 Norwegians and Meta-Analysis in 11,571 Subjects Indicate That Variants in the Hepatocyte Nuclear Factor 4 (HNF4A) P2 Region Are Associated With Type 2 Diabetes in Scandinavians

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

P2 Promoter Variants of the Hepatocyte Nuclear Factor 4 Gene Are Associated With Type 2 Diabetes in Mexican Americans

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

A common polymorphism in the upstream promoter region of the hepatocyte nuclear factor-4 alpha gene on chromosome 20q is associated with type 2 diabetes and appears to contribute to the evidence for linkage in an ashkenazi jewish population.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Common Variants of the Hepatocyte Nuclear Factor-4 P2 Promoter Are Associated With Type 2 Diabetes in the U.K. Population

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Evaluation of Common Variants in the Six Known Maturity-Onset Diabetes of the Young (MODY) Genes for Association With Type 2 Diabetes

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

A distant upstream promoter of the HNF-4alpha gene connects the transcription factors involved in maturity-onset diabetes of the young

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Population-specific risk of type 2 diabetes conferred by HNF4A P2 promoter variants: a lesson for replication studies

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Meta-analysis: State-of-the-Science

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Operating characteristics of a rank correlation test for publication bias

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Bias in meta-analysis detected by a simple, graphical test

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Efficient association study design via power-optimized tag SNP selection

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Genetic analysis of HNF4A polymorphisms in Caucasian-American type 2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Variants in hepatocyte nuclear factor 4alpha are modestly associated with type 2 diabetes in Pima Indians.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Gene-gene interactions betweenHNF4AandKCNJ11in predicting Type 2 diabetes in women

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Search of type 2 diabetes susceptibility gene on chromosome 20q.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Association study on chromosome 20q11.21-13.13 locus and its contribution to type 2 diabetes susceptibility in Japanese

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Effect of common polymorphisms in the HNF4? promoter on susceptibility to type 2 diabetes in the French Caucasian population

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Polymorphisms in the gene encoding hepatocyte nuclear factor-4alpha and susceptibility to type 2 diabetes in a Polish population

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

T130I mutation in HNF-4alpha gene is a loss-of-function mutation in hepatocytes and is associated with late-onset Type 2 diabetes mellitus in Japanese subjects

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Ethnicity, obesity, and risk of type 2 diabetes in women: a 20-year follow-up study

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Postprandial hyperglycemia and insulin sensitivity differ among lean young adults of different ethnicities.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Control of pancreas and liver gene expression by HNF transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Association studies of variants in the genes involved in pancreatic beta-cell function in type 2 diabetes in Japanese subjects

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.08.004

7 January 2021

Identifiers

10.1016/J.YMGME.2009.08.004

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19748811%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19748811%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

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