(Q84573168)

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The mechanism of lymphatic access of two cholesteryl ester transfer protein inhibitors (CP524,515 and CP532,623) and evaluation of their impact on lymph lipoprotein profiles

scientific article published on 16 July 2010

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20635194%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

The mechanism of lymphatic access of two cholesteryl ester transfer protein inhibitors (CP524,515 and CP532,623) and evaluation of their impact on lymph lipoprotein profiles (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20635194%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Natalie L Trevaskis

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20635194%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

William N. Charman

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20635194%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Christopher J.H. Porter

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20635194%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

author name string

Ravi M Shanker

2

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Europe PubMed Central

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7 February 2020

publication date

16 July 2010

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7 February 2020

Pharmaceutical Research

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20635194%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

27

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Europe PubMed Central

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7 February 2020

9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20635194%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1949-1964

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20635194%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholesteryl ester transfer protein (CETP) increases postprandial triglyceridaemia and delays triacylglycerol plasma clearance in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A proposed model for the assembly of chylomicrons

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A conscious dog model for assessing the absorption, enterocyte-based metabolism, and intestinal lymphatic transport of halofantrine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphatic transport of halofantrine in the triple-cannulated anesthetized rat model: effect of lipid vehicle dispersion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uptake of lipophilic drugs by plasma derived isolated chylomicrons: linear correlation with intestinal lymphatic bioavailability

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Role of the Intestinal Lymphatics in the Absorption of Two Highly Lipophilic Cholesterol Ester Transfer Protein Inhibitors (CP524,515 and CP532,623)

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The lymph lipid precursor pool is a key determinant of intestinal lymphatic drug transport.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of CETP by torcetrapib attenuates the atherogenicity of postprandial TG-rich lipoproteins in type IIB hyperlipidemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phospholipid transfer protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A kinetic evaluation of the absorption, efflux, and metabolism of verapamil in the autoperfused rat jejunum

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphatic Transport of Halofantrine in the Conscious Rat When Administered as Either the Free Base or the Hydrochloride Salt: Effect of Lipid Class and Lipid Vehicle Dispersion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of CETP inhibition in dyslipidemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bile increases intestinal lymphatic drug transport in the fasted rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effectiveness of inhibition of cholesteryl ester transfer protein by JTT-705 in combination with pravastatin in type II dyslipidemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic evidence for the absence of a functional cholesteryl ester transfer protein gene in mice and rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phospholipid transfer protein deficiency impairs apolipoprotein-B secretion from hepatocytes by stimulating a proteolytic pathway through a relative deficiency of vitamin E and an increase in intracellular oxidants

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Description of the torcetrapib series of cholesteryl ester transfer protein inhibitors, including mechanism of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The composition and structure of lymph chylomicrons in dog, rat, and man

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detecting distant relatives of mammalian LPS-binding and lipid transport proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An examination of the interplay between enterocyte-based metabolism and lymphatic drug transport in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of molecular physicochemical properties and apolipoproteins in association of drugs with triglyceride-rich lipoproteins: in-silico prediction of uptake by chylomicrons

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relationship between plasma high density lipoprotein cholesterol levels and cholesteryl ester transfer protein activity in six species of healthy experimental animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholesteryl ester transfer protein inhibition, high-density lipoprotein metabolism and heart disease risk reduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible role for intracellular cholesteryl ester transfer protein in adipocyte lipid metabolism and storage

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the cholesteryl ester transfer protein inhibitor torcetrapib on apolipoprotein B100 metabolism in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The withdrawal of torcetrapib from drug development: implications for the future of drugs that alter HDL metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevation of plasma phospholipid transfer protein in transgenic mice increases VLDL secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phospholipid and cholesteryl ester transfer activities in plasma from 14 vertebrate species. Relation to atherogenesis susceptibility.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular events in the assembly of chylomicrons in rabbit enterocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased post-prandial triglyceride response and diminished remnant lipoprotein formation in cholesteryl ester transfer protein (CETP) deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of short-, medium-, and long-chain fatty acid-based vehicles on the absolute oral bioavailability and intestinal lymphatic transport of halofantrine and assessment of mass balance in lymph-cannulated and non-cannulated rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of human BPI (bactericidal/permeability-increasing protein) and implications for related proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microsomal triglyceride transfer protein and its role in apoB-lipoprotein assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/20635194

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11095-010-0199-2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20635194%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20635194%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

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