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In vitro studies of the toxicity of nucleoside analogues used in the treatment of HIV infection
scientific article published on 01 August 1994
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Europe PubMed Central
PubMed publication ID
20692986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20692986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
title
In vitro studies of the toxicity of nucleoside analogues used in the treatment of HIV infection
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20692986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20692986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
author name string
O. P. Flint
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
20692986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20692986
retrieved
18 June 2024
language of work or name
English
1 reference
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National Center for Biotechnology Information
PubMed publication ID
20692986
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20692986
retrieved
18 June 2024
publication date
1 August 1994
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Europe PubMed Central
PubMed publication ID
20692986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20692986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
full work available at URL
https://api.elsevier.com/content/article/PII:0887233394900426?httpAccept=text/xml
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
https://api.elsevier.com/content/article/PII:0887233394900426?httpAccept=text/plain
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
published in
Toxicology in Vitro
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20692986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20692986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
volume
8
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20692986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20692986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
issue
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20692986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20692986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
page(s)
677-683
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20692986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20692986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
cites work
Depletion of muscle mitochondrial DNA in AIDS patients with zidovudine-induced myopathy
series ordinal
2
1 reference
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Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
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18 June 2024
Biogenesis of mitochondria
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Crossref
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10.1016/0887-2333(94)90042-6
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18 June 2024
2',3'-dideoxycytidine (ddC) toxic neuropathy: a study of 52 patients
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Crossref
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10.1016/0887-2333(94)90042-6
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Severe polymyositis-like syndrome associated with zidovudine therapy of AIDS and ARC.
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10.1016/0887-2333(94)90042-6
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18 June 2024
A model for fast axonal transport.
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18 June 2024
Azidothymidine-induced depression of murine hemopoietic progenitor cells
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10.1016/0887-2333(94)90042-6
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18 June 2024
In vitro toxicity and metabolism of 2',3'-dideoxycytidine, an inhibitor of human immunodeficiency virus infectivity
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10.1016/0887-2333(94)90042-6
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18 June 2024
Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity
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Crossref
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10.1016/0887-2333(94)90042-6
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18 June 2024
Phase I study of 2′-3′-dideoxyinosine administered orally twice daily to patients with AIDS or AIDS-related complex and hematologic intolerance to zidovudine
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Crossref
DOI
10.1016/0887-2333(94)90042-6
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18 June 2024
Antiretroviral therapy: reverse transcriptase inhibition
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Crossref
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10.1016/0887-2333(94)90042-6
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18 June 2024
Once-daily administration of 2',3'-dideoxyinosine (ddI) in patients with the acquired immunodeficiency syndrome or AIDS-related complex. Results of a Phase I trial
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10.1016/0887-2333(94)90042-6
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18 June 2024
3'-Azido-3'-deoxythymidine (AZT) inhibits proliferation in vitro of human haematopoietic progenitor cells
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10.1016/0887-2333(94)90042-6
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18 June 2024
Mitochondrial myopathy caused by long-term zidovudine therapy
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Crossref
DOI
10.1016/0887-2333(94)90042-6
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18 June 2024
Reversible axonal neuropathy from the treatment of AIDS and related disorders with 2',3'-dideoxycytidine (ddC).
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10.1016/0887-2333(94)90042-6
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18 June 2024
Didanosine. A review of its antiviral activity, pharmacokinetic properties and therapeutic potential in human immunodeficiency virus infection
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21
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Crossref
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10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Zalcitabine compared with zidovudine in patients with advanced HIV-1 infection who received previous zidovudine therapy
series ordinal
23
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Nature and incidence of peripheral nerve syndromes in HIV infection
series ordinal
24
1 reference
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Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Comparison of dideoxynucleoside drugs (DDI and zidovudine) and induction of hematopoietic toxicity using normal human bone marrow cells in vitro
series ordinal
25
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Differential phosphorylation of azidothymidine, dideoxycytidine, and dideoxyinosine in resting and activated peripheral blood mononuclear cells
series ordinal
27
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Zidovudine-associated myopathy
series ordinal
28
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Azidothymidine associated with bone marrow failure in the acquired immunodeficiency syndrome (AIDS)
series ordinal
29
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Anti-HIV drugs: comparative toxicities in murine fetal liver and bone marrow erythroid progenitor cells
series ordinal
30
1 reference
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Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
In vivo and in vitro effects of the azidothymidine analog dideoxyinosine on the exocrine pancreas of the rat
series ordinal
31
1 reference
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Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Thiol reduction of 3'-azidothymidine to 3'-aminothymidine: kinetics and biomedical implications
series ordinal
32
1 reference
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Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
3'-azido-3'-deoxythymidine (AZT) monophosphate: an inhibitor of exonucleolytic repair of AZT-terminated DNA
series ordinal
33
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Zidovudine-associated myopathy
series ordinal
34
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Cardiomyopathy Associated with Antiretroviral Therapy in Patients with HIV Infection: A Report of Six Cases
series ordinal
35
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Major growth reduction and minor decrease in mitochondrial enzyme activity in cultured human muscle cells after exposure to zidovudine
series ordinal
36
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
In vitro bone marrow toxicity of nucleoside analogs against human immunodeficiency virus
series ordinal
37
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Inhibition of bone marrow myelopoiesis and erythropoiesis in vitro by anti-retroviral nucleoside derivatives
series ordinal
38
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Antiviral agents
series ordinal
40
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
The pc12 cell as a model for studies of the mechanism of induction of peripheral neuropathy by anti-HIV-1 dideoxynucleoside analogs
series ordinal
41
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Extended follow-up of peripheral neuropathy in patients with AIDS and AIDS-related complex treated with dideoxyinosine
series ordinal
43
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
2',3'-dideoxyinosine (ddI) in patients with the acquired immunodeficiency syndrome or AIDS-related complex. A phase I trial
series ordinal
44
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Abnormal skeletal and cardiac muscle mitochondria induced by zidovudine (AZT) in human muscle in vitro and in an animal model
series ordinal
45
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Zidovudine induces molecular, biochemical, and ultrastructural changes in rat skeletal muscle mitochondria
series ordinal
46
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Specificity of heme for hemopoietic recovery from AZT toxicity
series ordinal
50
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Experimental studies of the hematologic and immune system toxicity of nucleoside derivatives used against HIV infection
series ordinal
51
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Overview of the preclinical development of an antiretroviral drug, 2',3'-dideoxyinosine
series ordinal
52
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Zidovudine and bone marrow
series ordinal
54
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Azidothymidine inhibits mitogen stimulated growth and DNA-repair in human peripheral lymphocytes
series ordinal
55
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
New antiretroviral agents in the clinic.
series ordinal
56
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Nucleoside Analogues as Chemotherapeutic Agents: A Review
series ordinal
58
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Ultrastructural characteristics and DNA immunocytochemistry in human immunodeficiency virus and zidovudine-associated myopathies
series ordinal
60
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial
series ordinal
63
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Hematological effects of 2',3'-dideoxycytidine in rabbits
series ordinal
64
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Overview of phase I trials of 2',3'-dideoxyinosine (ddI) conducted on adult patients
series ordinal
65
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Studies on the inhibition of mitochondrial DNA replication by 3'-azido-3'-deoxythymidine and other dideoxynucleoside analogs which inhibit HIV-1 replication
series ordinal
67
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Myopathies associated with human immunodeficiency virus and zidovudine: can their effects be distinguished?
series ordinal
68
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Nucleoside analogs: similarities and differences
series ordinal
69
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Clinical pharmacokinetics of 3'-azido-3'-deoxythymidine (zidovudine) and catabolites with formation of a toxic catabolite, 3'-amino-3'-deoxythymidine
series ordinal
71
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Hematologic toxicity of AZT and ddC administered as single agents and in combination to rats and mice
series ordinal
72
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Phase I study of 2',3'-dideoxyinosine: experience with 19 patients at New York University Medical Center
series ordinal
73
1 reference
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Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
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18 June 2024
A study of toxicity and comparative therapeutic efficacy of vindesine-prednisone vs. vincristine-prednisone in children with acute lymphoblastic leukemia in relapse. A Pediatric Oncology Group study
series ordinal
74
1 reference
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Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Participation of the mitochondrial genome in the differentiation of neuroblastoma cells
series ordinal
75
1 reference
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Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Phase I studies of 2',3'-dideoxycytidine in severe human immunodeficiency virus infection as a single agent and alternating with zidovudine (AZT).
series ordinal
77
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Long-term toxicity/activity profile of 2',3'-dideoxyinosine in AIDS or AIDS-related complex
series ordinal
78
1 reference
stated in
Crossref
DOI
10.1016/0887-2333(94)90042-6
reference URL
https://api.crossref.org/works/10.1016/0887-2333(94)90042-6
retrieved
18 June 2024
Identifiers
DOI
10.1016/0887-2333(94)90042-6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20692986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20692986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
PubMed publication ID
20692986
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20692986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20692986%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
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