(Q84818875)

English

Astaxanthin inhibits tumor invasion by decreasing extracellular matrix production and induces apoptosis in experimental rat colon carcinogenesis by modulating the expressions of ERK-2, NFkB and COX-2

scientific article published on 30 October 2009

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876598%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Astaxanthin inhibits tumor invasion by decreasing extracellular matrix production and induces apoptosis in experimental rat colon carcinogenesis by modulating the expressions of ERK-2, NFkB and COX-2 (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876598%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Ponnuraj Nagendraprabhu

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876598%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Ganapasam Sudhandiran

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876598%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

publication date

30 October 2009

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876598%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Investigational New Drugs

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876598%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

29

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876598%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876598%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

207-224

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876598%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

https://scigraph.springernature.com/pub.10.1007/s10637-009-9342-5

0 references

Cyclooxygenases: structural, cellular, and molecular biology

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell death: the significance of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Investigations into the metabolism and mode of action of the colon carcinogen 1, 2-dimethylhydrazine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the serine/threonine protein kinase AKT during the progression of colorectal neoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An apple a day may hold colorectal cancer at bay: recent evidence from a case-control study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinases as novel biomarkers and potential therapeutic targets in human cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinases: molecular aspects of their roles in tumour invasion and metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor action of curcumin in human papillomavirus associated cells involves downregulation of viral oncogenes, prevention of NFkB and AP-1 translocation, and modulation of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic significance of proliferating cell nuclear antigen expression in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of the APC tumor suppressor protein with catenins

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear factor kappa B: important transcription factor and therapeutic target

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carotenoids suppress proliferating cell nuclear antigen and cyclin D1 expression in oral carcinogenic models.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of cyclooxygenase-1 and -2 in human colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of collagenase-3 expression in human breast carcinomas is mediated by stromal-epithelial cell interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemoprevention of mouse urinary bladder carcinogenesis by the naturally occurring carotenoid astaxanthin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of matrix metalloproteinases (MMPs) in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemoprevention of colorectal carcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mast cell chymase induces conjunctival epithelial cell apoptosis by a mechanism involving degradation of fibronectin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinase-9 contributes to intestinal tumourigenesis in the adenomatous polyposis coli multiple intestinal neoplasia mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspases: enemies within

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A protective role of mast cells in intestinal tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigallocatechin-3-gallate augments antioxidant activities and inhibits inflammation during bleomycin-induced experimental pulmonary fibrosis through Nrf2-Keap1 signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of carotenoids in the ovaries of marine fish and shellfish

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antioxidative and antiproliferative effects of astaxanthin during the initiation stages of 1,2-dimethyl hydrazine-induced experimental colon carcinogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-kappaB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mast cells in the development of adaptive immune responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A plant flavonoid fisetin induces apoptosis in colon cancer cells by inhibition of COX2 and Wnt/EGFR/NF-kappaB-signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haematococcus astaxanthin: applications for human health and nutrition

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of oxidative injury of biological membranes by astaxanthin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor beta 1 and metalloproteinase-9 overexpression in colorectal cancer (CC) and adenoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer statistics, 2006

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of mast cells in tumour angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mast cell-mediated tumor-cell cytotoxicity. Role of the peroxidase system

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mast cells: the Jekyll and Hyde of tumor growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PCNA: structure, functions and interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antihypertensive potential and mechanism of action of astaxanthin: III. Antioxidant and histopathological effects in spontaneously hypertensive rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical study on p53, H-rasp21, c-erbB-2 protein and PCNA expression in HCC tissues of Han and minority ethnic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of matrix metalloproteinase expression in tumor invasion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis and colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor protects epithelial-derived cells from tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by inhibiting cytochrome c release.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor cyclooxygenase-2 levels correlate with tumor invasiveness in human hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-kappaB as a therapeutic target in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemoprevention of rat oral carcinogenesis by naturally occurring xanthophylls, astaxanthin and canthaxanthin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-kappaB: linking inflammation and immunity to cancer development and progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinase-2 and tissue inhibitor of metallo-proteinase-2 in colorectal carcinoma invasion and metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New functions for the matrix metalloproteinases in cancer progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mast cells as target in cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Annexin V binding assay as a tool to measure apoptosis in differentiated neuronal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

iNOS enhances rat intestinal apoptosis after ischemia-reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antimutagens as cancer chemopreventive agents in the diet

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane type-matrix metalloproteinases and tumor progression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclooxygenase regulates angiogenesis induced by colon cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antioxidant and redox regulation of gene transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting the ERK signaling pathway in cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis: a review of programmed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-talk between PI3K/Akt and MEK/ERK pathways mediates endoplasmic reticulum stress-induced cell cycle progression and cell death in human hepatocellular carcinoma cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear factor-kappaB: the enemy within

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clearance of apoptotic cells by phagocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of bacterial metabolism in the intestine on colorectal tumors induced by 1,2-dimethylhydrazine in transgenic mice harboring human prototype c-Ha-ras genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing I(kappa)B kinase-dependent NF-kappaB activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway decreases DNA methylation in colon cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory effect of the AMPK-COX-2 signaling pathway in curcumin-induced apoptosis in HT-29 colon cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microvessel density, mast cell density and thymidine phosphorylase expression in oral squamous carcinoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor promotes MDA-MB-231 breast cancer cell migration through a phosphatidylinositol 3'-kinase and phospholipase C-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astaxanthin: a novel potential treatment for oxidative stress and inflammation in cardiovascular disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the carotenoids in the muscle of salmon--V. Combination of astaxanthin and canthaxanthin with bovine serum albumin and egg albumin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial DNA damage triggers mitochondrial dysfunction and apoptosis in oxidant-challenged lung endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19876598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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