(Q84943449)

English

Protection from non-alcoholic steatohepatitis and liver tumourigenesis in high fat-fed insulin receptor substrate-1-knockout mice despite insulin resistance

scientific article published on 07 September 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Protection from non-alcoholic steatohepatitis and liver tumourigenesis in high fat-fed insulin receptor substrate-1-knockout mice despite insulin resistance (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

non-alcoholic steatohepatitis

1 reference

based on heuristic

inferred from title

insulin resistance

1 reference

based on heuristic

inferred from title

author name string

A Nakamura

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

K Tajima

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

K Zolzaya

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

K Sato

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

R Inoue

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

M Yoneda

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

K Fujita

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Y Nozaki

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

K C Kubota

9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

H Haga

10

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

N Kubota

11

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Y Nagashima

12

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

A Nakajima

13

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

S Maeda

14

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

T Kadowaki

15

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Y Terauchi

16

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

publication date

7 September 2012

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

55

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

12

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

3382-3391

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955994%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

https://scigraph.springernature.com/pub.10.1007/s00125-012-2703-1

0 references

Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective versus total insulin resistance: a pathogenic paradox

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ablation of PI3K p110-α prevents high-fat diet-induced liver steatosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased serum leptin protects from adiposity despite the increased glucose uptake in white adipose tissue in mice lacking p85alpha phosphoinositide 3-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SnapShot: Insulin signaling pathways.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design and validation of a histological scoring system for nonalcoholic fatty liver disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and beta cell glucokinase genes. Genetic reconstitution of diabetes as a polygenic disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin signalling and the regulation of glucose and lipid metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered composition of fatty acids exacerbates hepatotumorigenesis during activation of the phosphatidylinositol 3-kinase pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt2 is required for hepatic lipid accumulation in models of insulin resistance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diet-induced hepatocellular carcinoma in genetically predisposed mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin, glucose and the increased risk of cancer in patients with type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Irs1 branch of the insulin signaling cascade plays a dominant role in hepatic nutrient homeostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetes and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High fat diet induced hepatic steatosis establishes a permissive microenvironment for colorectal metastases and promotes primary dysplasia in a murine model

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin inhibits transcription of IRS-2 gene in rat liver through an insulin response element (IRE) that resembles IREs of other insulin-repressed genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetes mellitus and the risk of cancer: results from a large-scale population-based cohort study in Japan

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetes and cancer: a consensus report.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissociation of Hepatic Steatosis and Insulin Resistance in Mice Overexpressing DGAT in the Liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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