(Q85003121)

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The t(6;9) associated DEK/CAN fusion protein targets a population of long-term repopulating hematopoietic stem cells for leukemogenic transformation

scientific article published on 09 September 2010

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20827285%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

The t(6;9) associated DEK/CAN fusion protein targets a population of long-term repopulating hematopoietic stem cells for leukemogenic transformation (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20827285%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Martin Ruthardt

5

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Europe PubMed Central

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13 February 2020

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C Oancea

1

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13 February 2020

B Rüster

2

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13 February 2020

R Henschler

3

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13 February 2020

E Puccetti

4

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13 February 2020

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9 September 2010

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13 February 2020

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13 February 2020

24

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13 February 2020

11

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13 February 2020

1910-1919

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13 February 2020

Normal and leukemic hematopoiesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.180

7 January 2021

based on heuristic

inferred from DOI database lookup

Oncogenic transcription factors in the human acute leukemias

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.180

7 January 2021

based on heuristic

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A previously unidentified alternatively spliced isoform of t(8;21) transcript promotes leukemogenesis

1 reference

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7 January 2021

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Gamma-catenin contributes to leukemogenesis induced by AML-associated translocation products by increasing the self-renewal of very primitive progenitor cells.

1 reference

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7 January 2021

based on heuristic

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Development of a D-FISH method to detect DEK/CAN fusion resulting from t(6;9)(p23;q34) in patients with acute myelogenous leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.180

7 January 2021

based on heuristic

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DEK-CAN molecular monitoring of myeloid malignancies could aid therapeutic stratification.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.180

7 January 2021

based on heuristic

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Regulation of histone acetyltransferase activity of p300 and PCAF by proto-oncogene protein DEK.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.180

7 January 2021

based on heuristic

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Functional domains of the ubiquitous chromatin protein DEK.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.180

7 January 2021

based on heuristic

inferred from DOI database lookup

The ubiquitous chromatin protein DEK alters the structure of DNA by introducing positive supercoils

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.180

7 January 2021

based on heuristic

inferred from DOI database lookup

The human DEK proto-oncogene is a senescence inhibitor and an upregulated target of high-risk human papillomavirus E7

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.180

7 January 2021

based on heuristic

inferred from DOI database lookup

The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.180

7 January 2021

based on heuristic

inferred from DOI database lookup

Overexpression of the nucleoporin CAN/NUP214 induces growth arrest, nucleocytoplasmic transport defects, and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.180

7 January 2021

based on heuristic

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Targeting of the N-terminal coiled coil oligomerization interface by a helix-2 peptide inhibits unmutated and imatinib-resistant BCR/ABL.

1 reference

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7 January 2021

based on heuristic

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Arsenic but not all-trans retinoic acid overcomes the aberrant stem cell capacity of PML/RARalpha-positive leukemic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.180

7 January 2021

based on heuristic

inferred from DOI database lookup

Valproic acid stimulates proliferation and self-renewal of hematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.180

7 January 2021

based on heuristic

inferred from DOI database lookup

MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.180

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of hematopoietic stem/progenitor cells: strength and drawbacks of functional assays

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.180

7 January 2021

based on heuristic

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Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.180

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.180

7 January 2021

based on heuristic

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Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.180

7 January 2021

based on heuristic

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PML-RARalpha initiates leukemia by conferring properties of self-renewal to committed promyelocytic progenitors

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.180

7 January 2021

based on heuristic

inferred from DOI database lookup

Cancer stem cells: lessons from leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.180

7 January 2021

based on heuristic

inferred from DOI database lookup

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