(Q85428268)

English

Proarrhythmic safety of repeat doses of mirabegron in healthy subjects: a randomized, double-blind, placebo-, and active-controlled thorough QT study

scientific article published on 14 November 2012

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149929%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Proarrhythmic safety of repeat doses of mirabegron in healthy subjects: a randomized, double-blind, placebo-, and active-controlled thorough QT study (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149929%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149929%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

author name string

E M van Gelderen

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149929%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

J H Lee

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149929%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

D L Kowalski

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149929%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

M Yen

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149929%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

R Goldwater

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149929%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

S K Mujais

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149929%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

M P Schaddelee

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149929%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

P de Koning

9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149929%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

A Kaibara

10

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149929%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

S S Moy

11

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149929%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

J J Keirns

12

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149929%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

publication date

14 November 2012

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149929%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Clinical Pharmacology & Therapeutics

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149929%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

92

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149929%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149929%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

696-706

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149929%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Effect of (R)-2-(2-aminothiazol-4-yl)-4'-{2-[(2-hydroxy-2-phenylethyl)amino]ethyl} acetanilide (YM178), a novel selective beta3-adrenoceptor agonist, on bladder function

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Reviewing the ICS 2002 terminology report: the ongoing debate

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Definition and epidemiology of overactive bladder

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

An overview of the clinical use of antimuscarinics in the treatment of overactive bladder

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Drug-induced torsades de pointes and implications for drug development.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Methodologies to characterize the QT/corrected QT interval in the presence of drug-induced heart rate changes or other autonomic effects.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

The Duration of Systole in an Electrocardiogram in Normal Humans and in Patients with Heart Disease*

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Problems of heart rate correction in assessment of drug-induced QT interval prolongation.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

The imprecision in heart rate correction may lead to artificial observations of drug induced QT interval changes

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Relation between QT and RR intervals is highly individual among healthy subjects: implications for heart rate correction of the QT interval

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Subject-specific profiles of QT/RR hysteresis

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Dynamic properties of selected repolarization descriptors

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

National community prevalence of overactive bladder in the United States stratified by sex and age.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Assessing electrocardiographic data quality and possible replacement of pharmacologic positive control in thorough QT/QTc studies by investigations of drug-free QTc stability.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Thorough QT Studies: Questions and Quandaries

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

The effect of moxifloxacin on QTc and implications for the design of thorough QT studies

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Differences between study-specific and subject-specific heart rate corrections of the QT interval in investigations of drug induced QTc prolongation.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Accurately measured and properly heart-rate corrected QTc intervals show little daytime variability

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

A practical approach to torsade de pointes

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Tolterodine treatment improves storage symptoms suggestive of overactive bladder in men treated with alpha-blockers

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of P-glycoprotein in pharmacokinetics: clinical implications

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Cardiac effects of muscarinic receptor antagonists used for voiding dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Torsades de pointes ventricular tachycardia and terodiline

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Torsades de pointes complicating treatment with terodiline

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

QT and QTc interval with standard and supratherapeutic doses of darifenacin, a muscarinic M3 selective receptor antagonist for the treatment of overactive bladder

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Thorough QT study of the effect of fesoterodine on cardiac repolarization

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Thorough QT study with recommended and supratherapeutic doses of tolterodine

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Systematic comparisons of electrocardiographic morphology increase the precision of QT interval measurement

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Spatial, temporal and wavefront direction characteristics of 12-lead T-wave morphology.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Assessment of noise in digital electrocardiograms.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Thorough QT/QTc study in patients with advanced Parkinson's disease: cardiac safety of rotigotine

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

QT-RR relationship in healthy subjects exhibits substantial intersubject variability and high intrasubject stability

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Should baseline be a covariate or dependent variable in analyses of change from baseline in clinical trials?

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Small sample inference for fixed effects from restricted maximum likelihood.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Concentration-QT relationships play a key role in the evaluation of proarrhythmic risk during regulatory review.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.181

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/CLPT.2012.181

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149929%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149929%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q85428268&oldid=1455639160"