(Q85642717)

English

Long-term phosphodiesterase 5 inhibitor administration reduces inflammatory markers and heat-shock proteins in cavernous tissue of Zucker diabetic fatty rat (ZDF/fa/fa)

scientific article published on 23 July 2015

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26202338%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Long-term phosphodiesterase 5 inhibitor administration reduces inflammatory markers and heat-shock proteins in cavernous tissue of Zucker diabetic fatty rat (ZDF/fa/fa) (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26202338%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

author name string

J E Toblli

1

1 reference

Europe PubMed Central

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20 February 2020

G Cao

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26202338%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

M Angerosa

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26202338%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

M Rivero

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26202338%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

publication date

23 July 2015

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26202338%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

International Journal of Impotence Research

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26202338%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

27

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26202338%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26202338%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

182-190

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26202338%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

https://scigraph.springernature.com/pub.10.1038/ijir.2015.13

0 references

Nonalcoholic steatohepatitis as a novel player in metabolic syndrome-induced erectile dysfunction: an experimental study in the rabbit.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphodiesterase 5 inhibitors in the treatment of erectile dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Small artery structure and hypertension: adaptive changes and target organ damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional and morphological improvement in erectile tissue of hypertensive rats by long-term combined therapy with phosphodiesterase type 5 inhibitor and losartan

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A sensitive spectrophotometric method for the determination of superoxide dismutase activity in tissue extracts

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early onset of fibrosis within the arterial media in a rat model of type 2 diabetes mellitus with erectile dysfunction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of action of phosphodiesterase type 5 inhibition in metabolic syndrome-associated prostate alterations: an experimental study in the rabbit

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum biomarker measurements of endothelial function and oxidative stress after daily dosing of sildenafil in type 2 diabetic men with erectile dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A study comparing the effects of rosiglitazone and/or insulin treatments on streptozotocin induced diabetic (type I diabetes) rat aorta and cavernous tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term treatment with an angiotensin II receptor blocker decreases adipocyte size and improves insulin signaling in obese Zucker rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of malonaldehyde from phospholipid arachidonate during microsomal lipid peroxidation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo and in vitro effects of nebivolol on penile structures in hypertensive rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetes and cardiovascular disease: a statement for healthcare professionals from the American Heart Association

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sildenafil inhibits the up-regulation of phosphodiesterase type 5 elicited with nicotine and tumour necrosis factor-alpha in cavernosal vascular smooth muscle cells: mediation by superoxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between circulating cytokine levels, diabetes and insulin resistance in a population-based sample (CoLaus study).

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free radical-scavenging activity of Korean red ginseng for erectile dysfunction in non-insulin-dependent diabetes mellitus rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of high glucose-induced apoptosis and its relationship to diabetic complications

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ACE inhibition and AT1 receptor blockade prevent fatty liver and fibrosis in obese Zucker rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxynitrite formation from macrophage-derived nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum heat shock protein 27 antigen and antibody levels appear to be related to the macrovascular complications associated with insulin resistance: a pilot study

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sildenafil: an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Emerging role for TNF-α in erectile dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agonist-induced peroxynitrite production from endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sildenafil inhibits superoxide formation and prevents endothelial dysfunction in a mouse model of secondhand smoke induced erectile dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanistic insights into diabetes mellitus and oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-atherogenic effect of statins: role of nitric oxide, peroxynitrite and haem oxygenase-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The genetic inactivation of inducible nitric oxide synthase (iNOS) intensifies fibrosis and oxidative stress in the penile corpora cavernosa in type 1 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic treatment with tadalafil improves endothelial function in men with increased cardiovascular risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral sildenafil in the treatment of erectile dysfunction. Sildenafil Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of different antihypertensive drugs on cavernous tissue in experimental chronic renal insufficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiovascular protective effects of nebivolol in Zucker diabetic fatty rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiotensin-(1 7) stimulates the phosphorylation of JAK2, IRS-1 and Akt in rat heart in vivo: role of the AT1 and Mas receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Zucker-fatty rat: a review

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular pathology of oxidative stress in diabetic angiopathy: role of mitochondrial and cellular pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation and metabolic dysfunction: links to cardiovascular diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of poly(ADP-ribose) polymerase-1 activation in the pathogenesis of diabetic complications: endothelial dysfunction, as a common underlying theme

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin resistance and associated dysfunction of resistance vessels and arterial hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arterial elasticity in cardiovascular disease: focus on hypertension, metabolic syndrome and diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein measurement with the Folin phenol reagent

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The shock of aging: molecular chaperones and the heat shock response in longevity and aging--a mini-review

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The central role of vascular extracellular matrix and basement membrane remodeling in metabolic syndrome and type 2 diabetes: the matrix preloaded

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PDE5 inhibitors blunt inflammation in human BPH: a potential mechanism of action for PDE5 inhibitors in LUTS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetes and cardiovascular disease. The Framingham study

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of long-term administration of tadalafil on STZ-induced diabetic rats with erectile dysfunction via a local antioxidative mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of ACE inhibition and beta-blockade on female genital structures in spontaneously hypertensive rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TNF-alpha infusion impairs corpora cavernosa reactivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Zucker fatty rat as a genetic model of obesity and hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetics of arterial structure and function: towards new biomarkers for aortic stiffness?

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperglycaemia and oxidative stress upregulate HSP60 & HSP70 expression in HeLa cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular signaling and NO production

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic sildenafil improves erectile function and endothelium-dependent cavernosal relaxations in rats: lack of tachyphylaxis

1 reference

https://pubmed.ncbi.nlm.nih.gov/26202338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zucker (fa/fa) Rat

1 reference

https://api.crossref.org/works/10.1038%2FIJIR.2015.13

7 January 2021

based on heuristic

inferred from DOI database lookup

The Zucker fatty rat as a genetic model of obesity and hypertension

1 reference

https://api.crossref.org/works/10.1038%2FIJIR.2015.13

7 January 2021

based on heuristic

inferred from DOI database lookup

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