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Familial hypercholesterolaemia: PCSK9 inhibitors are coming
scientific article published on 01 October 2014
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25282517
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25282517%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 February 2020
title
Familial hypercholesterolaemia: PCSK9 inhibitors are coming
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25282517
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25282517%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 February 2020
author
Gerald Watts
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25282517
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25282517%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 February 2020
author name string
Raul D Santos
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25282517
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25282517%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 February 2020
language of work or name
English
0 references
publication date
1 October 2014
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25282517
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25282517%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 February 2020
published in
The Lancet
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25282517
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25282517%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 February 2020
volume
385
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25282517
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25282517%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 February 2020
issue
9965
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25282517
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25282517%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 February 2020
page(s)
307-310
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25282517
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25282517%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 February 2020
cites work
Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2814%2961702-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Familial hypercholesterolemia in the danish general population: prevalence, coronary artery disease, and cholesterol-lowering medication.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2814%2961702-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homozygous autosomal dominant hypercholesterolaemia in the Netherlands: prevalence, genotype-phenotype relationship, and clinical outcome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2814%2961702-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homozygous familial hypercholesterolemia: current perspectives on diagnosis and treatment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2814%2961702-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lipoprotein(a) Levels in Familial Hypercholesterolemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2814%2961702-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Efficacy of statins in familial hypercholesterolaemia: a long term cohort study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2814%2961702-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PCSK9: a convertase that coordinates LDL catabolism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2814%2961702-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Integrated guidance on the care of familial hypercholesterolaemia from the International FH Foundation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2814%2961702-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2814%2961702-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2814%2961702-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lipid-lowering treatment for homozygous familial hypercholesterolaemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2814%2961702-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
LDL cholesterol: controversies and future therapeutic directions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2814%2961702-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of a monoclonal antibody to PCSK9, REGN727/SAR236553, to reduce low-density lipoprotein cholesterol in patients with heterozygous familial hypercholesterolaemia on stable statin dose with or without ezetimibe therapy: a phase 2 randomised con
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2814%2961702-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Low-density lipoprotein cholesterol-lowering effects of AMG 145, a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 serine protease in patients with heterozygous familial hypercholesterolemia: the Reduction of LDL-C with PCSK9 In
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2814%2961702-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of the proprotein convertase subtilisin/kexin 9 monoclonal antibody, AMG 145, in homozygous familial hypercholesterolemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2814%2961702-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The inverse association of plasma lipoprotein(a) concentrations with apolipoprotein(a) isoform size is not due to differences in Lp(a) catabolism but to differences in production rate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2814%2961702-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Elevated remnant cholesterol causes both low-grade inflammation and ischemic heart disease, whereas elevated low-density lipoprotein cholesterol causes ischemic heart disease without inflammation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2814%2961702-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Normal levels of inflammatory markers in treated patients with familial hypercholesterolaemia: a cross-sectional study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2814%2961702-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A 52-week placebo-controlled trial of evolocumab in hyperlipidemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2814%2961702-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anti-PCSK9 antibody effectively lowers cholesterol in patients with statin intolerance: the GAUSS-2 randomized, placebo-controlled phase 3 clinical trial of evolocumab.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2814%2961702-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2814%2961702-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0140-6736(14)61702-5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25282517
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25282517%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 February 2020
PubMed publication ID
25282517
1 reference
stated in
Europe PubMed Central
PubMed publication ID
25282517
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25282517%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 February 2020
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