(Q86098274)

English

Essential role of the electroneutral Na+-HCO3- cotransporter NBCn1 in murine duodenal acid-base balance and colonic mucus layer build-up in vivo

scientific article published on 11 February 2013

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401617%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Essential role of the electroneutral Na+-HCO3- cotransporter NBCn1 in murine duodenal acid-base balance and colonic mucus layer build-up in vivo (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401617%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Oliver Bachmann

9

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23 February 2020

Jeppe Praetorius

11

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Europe PubMed Central

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23 February 2020

author name string

Anurag Kumar Singh

1

1 reference

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23 February 2020

Weiliang Xia

2

1 reference

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23 February 2020

Brigitte Riederer

3

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23 February 2020

Marina Juric

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401617%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Junhua Li

5

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401617%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Wen Zheng

6

1 reference

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PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401617%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Ayhan Cinar

7

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401617%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Fang Xiao

8

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401617%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Penghong Song

10

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401617%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Christian Aalkjaer

12

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401617%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Ursula Seidler

13

1 reference

Europe PubMed Central

PubMed publication ID

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23 February 2020

publication date

11 February 2013

1 reference

Europe PubMed Central

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23 February 2020

Journal of Physiology

1 reference

Europe PubMed Central

PubMed publication ID

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23 February 2020

591

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401617%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401617%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

2189-2204

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401617%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Calcium and pH-dependent packing and release of the gel-forming MUC2 mucin

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal cGMP kinase I is essential for stimulation of duodenal bicarbonate secretion by luminal acid.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DeltaF508 CFTR protein expression in tissues from patients with cystic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gastroduodenal mucus bicarbonate barrier: protection against acid and pepsin

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

pH-dependent intraluminal organization of mucin granules in live human mucous/goblet cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of the anion exchanger SLC26A6 in prostaglandin E2- but not forskolin-stimulated duodenal HCO3- secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carbachol increases Na+-HCO3- cotransport activity in murine colonic crypts in a M3-, Ca2+/calmodulin-, and PKC-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Review article: duodenal bicarbonate - mucosal protection, luminal chemosensing and acid-base balance

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NHE3 inhibition by cAMP and Ca2+ is abolished in PDZ-domain protein PDZK1-deficient murine enterocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular expression of SLC4-derived Na+-dependent anion transporters in selected human tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibody-independent localization of the electroneutral Na+-HCO3- cotransporter NBCn1 (slc4a7) in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CFTR and its key role in in vivo resting and luminal acid-induced duodenal HCO3- secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cAMP-dependent and cholinergic regulation of the electrogenic intestinal/pancreatic Na+/HCO3- cotransporter pNBC1 in human embryonic kidney (HEK293) cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of down-regulated in adenoma anion exchanger in HCO3- secretion across murine duodenum

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The electroneutral Na⁺:HCO₃⁻ cotransporter NBCn1 is a major pHi regulator in murine duodenum.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rescue of epithelial HCO3- secretion in murine intestine by apical membrane expression of the cystic fibrosis transmembrane conductance regulator mutant F508del

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of transport abnormalities in duodenal mucosa and duodenal enterocytes from patients with cystic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of Na(+)HCO(3)(-) cotransporter NBC1, Na(+)/H(+) exchanger NHE1, and carbonic anhydrase in rabbit duodenal bicarbonate secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular localization of the cystic fibrosis transmembrane conductance regulator in mouse intestinal tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular and functional evidence for electrogenic and electroneutral Na(+)-HCO(3)(-) cotransporters in murine duodenum.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The adherent gastrointestinal mucus gel layer: thickness and physical state in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute adaptive cellular base uptake in rat duodenal epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular bicarbonate protects rat duodenal mucosa from acid-induced injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acidic pH and increasing [Ca(2+)] reduce the swelling of mucins in primary cultures of human cervical cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cAMP-mediated regulation of murine intestinal/pancreatic Na+/HCO3- cotransporter subtype pNBC1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oscillations of pH inside the secretory granule control the gain of Ca2+ release for signal transduction in goblet cell exocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cystic fibrosis transmembrane conductance regulator and Na+ channel subunits mRNA transcripts, and Cl- efflux, show a different distribution in rat duodenum and colon.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Applicability of different antibodies for the immunohistochemical localization of CFTR in respiratory and intestinal tissues of human and murine origin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mucin exocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three distinct mechanisms of HCO3- secretion in rat distal colon

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Na+/H+ exchanger isoform 2 is the predominant NHE isoform in murine colonic crypts and its lack causes NHE3 upregulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acid-stimulated duodenal bicarbonate secretion involves a CFTR-mediated transport pathway in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Duodenal acidity "sensing" but not epithelial HCO3- supply is critically dependent on carbonic anhydrase II expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normal mouse intestinal mucus release requires cystic fibrosis transmembrane regulator-dependent bicarbonate secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretagogue stimulation enhances NBCe1 (electrogenic Na(+)/HCO(3)(-) cotransporter) surface expression in murine colonic crypts

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mucin gene deficiency in mice impairs host resistance to an enteric parasitic infection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of epithelial HCO3⁻ transport in mucin secretion: lessons from cystic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological relevance of cell-specific distribution patterns of CFTR, NKCC1, NBCe1, and NHE3 along the crypt-villus axis in the intestine

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Importance and regulation of the colonic mucus barrier in a mouse model of colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of Na+,HCO₃⁻ cotransporter NBCn1 (slc4a7) inhibits NO-mediated vasorelaxation, smooth muscle Ca²⁺ sensitivity, and hypertension development in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of downregulated in adenoma (DRA) impairs mucosal HCO3(-) secretion in murine ileocolonic inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A functional CFTR protein is required for mouse intestinal cAMP-, cGMP- and Ca(2+)-dependent HCO3- secretion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23401617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1113/JPHYSIOL.2012.247874

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401617%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401617%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

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