(Q86195048)

English

Calcitonin Gene-Related Peptide Regulates Cardiomyocyte Survival through Regulation of Oxidative Stress by PI3K/Akt and MAPK Signaling Pathways

scientific article published on 01 January 2014

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scholarly article

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24 February 2020

Calcitonin Gene-Related Peptide Regulates Cardiomyocyte Survival through Regulation of Oxidative Stress by PI3K/Akt and MAPK Signaling Pathways (English)

1 reference

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24 February 2020

author name string

Nsini A Umoh

1

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24 February 2020

Robin K Walker

2

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24 February 2020

Richard M Millis

3

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24 February 2020

Mustafa Al-Rubaiee

4

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24 February 2020

Pandu R Gangula

5

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24 February 2020

Georges E Haddad

6

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24 February 2020

publication date

1 January 2014

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24 February 2020

2

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24 February 2020

1

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24 February 2020

1007

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24 February 2020

Comparing the molecular pharmacology of CGRP and adrenomedullin

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of amylin in the physiology of glycemic control.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nongenomic, endothelium-independent effects of estrogen on human coronary smooth muscle are mediated by type I (neuronal) NOS and PI3-kinase-Akt signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Akt-nitric oxide-cGMP pathway contributes to nerve growth factor-mediated neurite outgrowth in apolipoprotein E knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of the proinflammatory cytokines tumor necrosis factor-alpha, IL-1 beta, and IL-6 but not IL-8 in the development of heat hyperalgesia: effects on heat-evoked calcitonin gene-related peptide release from rat skin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amylin is associated with delayed gastric emptying in critically ill children

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clonidine induces calcitonin gene-related peptide expression via nitric oxide pathway in endothelial cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evolutionary history of the calcitonin gene-related peptide family in vertebrates revealed by comparative genomic analyses

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of IGF-1 on I(K) and I(K1) Channels via PI3K/Akt Signaling in Neonatal Cardiac Myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of NF-kappaB activity and enhancement of apoptosis by the neuropeptide calcitonin gene-related peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of calcitonin gene-related peptide expression in dorsal root ganglia of rats by female sex steroid hormones.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanism of calcitonin gene-related peptide-containing nerve innervation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intermedin elicits a negative inotropic effect in rat papillary muscles mediated by endothelial-derived nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adrenomedullin gene delivery attenuates myocardial infarction and apoptosis after ischemia and reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor regulates expression of neuropeptide genes in adult sensory neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mesenteric arterial relaxation to calcitonin gene-related peptide is increased during pregnancy and by sex steroid hormones.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-talk between MAPKs and PI-3K pathways alters the functional density of I(K) channels in hypertrophied hearts

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcitonin gene-related peptide in vivo positive inotropy is attributable to regional sympatho-stimulation and is blunted in congestive heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G-protein βγ subunits in vasorelaxing and anti-endothelinergic effects of calcitonin gene-related peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitogen-activated protein kinases in apoptosis regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A third human CALC (pseudo)gene on chromosome 11.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor-induced stimulation of p38 mitogen-activated protein kinase in PC12 cells is partially mediated via G(i/o) proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compensation of the AKT signaling by ERK signaling in transgenic mice hearts overexpressing TRIM72.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inotropic and lusitropic effects of calcitonin gene-related peptide in the heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gs and Gi coupling of adrenomedullin in adult rat ventricular myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two mechanisms involved in trigeminal CGRP release: implications for migraine treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Basal and IGF-I-dependent regulation of potassium channels by MAP kinases and PI3-kinase during eccentric cardiac hypertrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positive inotropic effect of calcitonin gene-related peptide mediated by cyclic AMP in guinea pig heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maternal plasma levels of endothelial dysfunction mediators including AM, CGRP, sICAM-1 and tHcy in pre-eclampsia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative activation of Ca(2+)/calmodulin-activated kinase II mediates ER stress-induced cardiac dysfunction and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dilation by CGRP of middle meningeal artery and reversal by sumatriptan in normal volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The myocardial response to adrenomedullin involves increased cAMP generation as well as augmented Akt phosphorylation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of L-type inward calcium channel activity by captopril and angiotensin II via the phosphatidyl inositol 3-kinase pathway in cardiomyocytes from volume-overload hypertrophied rat hearts

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcitonin gene-related peptide ameliorates hyperoxia-induced lung injury in neonatal rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CGRP inhibits norepinephrine induced apoptosis with restoration of Bcl-2/Bax in cultured cardiomyocytes of rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Islet amyloid polypeptide in the gut and pancreas: localization, ontogeny and gut motility effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcitonin Gene-Related Peptide-Mediated Enhancement of Purinergic Neuron/Glia Communication by the Algogenic Factor Bradykinin in Mouse Trigeminal Ganglia from Wild-Type and R192Q Cav2.1 Knock-In Mice: Implications for Basic Mechanisms of Migraine P

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt signalling in health and disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the instantaneous inward rectifier and the delayed outward rectifier potassium channels by Captopril and Angiotensin II via the Phosphoinositide-3 kinase pathway in volume-overload-induced hypertrophied cardiac myocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-activity relationships for α-calcitonin gene-related peptide.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role for voltage gated calcium channels in calcitonin gene-related peptide release in the rat trigeminovascular system

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphine peripheral analgesia depends on activation of the PI3Kgamma/AKT/nNOS/NO/KATP signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reducing ischaemia/reperfusion injury through delta-opioid-regulated intrinsic cardiac adrenergic cells: adrenopeptidergic co-signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel Peptide Antagonists of Adrenomedullin and Calcitonin Gene-Related Peptide Receptors: Identification, Pharmacological Characterization, and Interactions with Position 74 in Receptor Activity-Modifying Protein 1/3

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ERK1/2 and p38 MAPKs are complementarily involved in estradiol 17ß-D-glucuronide-induced cholestasis: crosstalk with cPKC and PI3K.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25478604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25478604%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25478604%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

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