(Q87049212)

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IGFBP-3/transferrin/transferrin receptor 1 complexes as principal mediators of IGFBP-3 delivery to colon cells in non-cancer and cancer tissues

scientific article published on 31 March 2015

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4 March 2020

IGFBP-3/transferrin/transferrin receptor 1 complexes as principal mediators of IGFBP-3 delivery to colon cells in non-cancer and cancer tissues (English)

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4 March 2020

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author name string

Goran Miljuš

1

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4 March 2020

Vesna Malenković

2

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Blagoje Đukanović

3

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4 March 2020

Nikola Kolundžić

4

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publication date

31 March 2015

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Experimental and Molecular Pathology

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98

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431-438

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4 March 2020

High sensitivity enzyme-linked immunosorbent assay (ELISA) method for measuring protein carbonyl in samples with low amounts of protein.

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Insulin-like growth factor-binding protein-3 binds fibrinogen and fibrin

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IGFBP-3 binds GRP78, stimulates autophagy and promotes the survival of breast cancer cells exposed to adverse microenvironments

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The ferritins: molecular properties, iron storage function and cellular regulation

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Iron deprivation in cancer--potential therapeutic implications

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Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer

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Differential expression of IGF-binding protein-3 in normal and malignant colon and its influence on apoptosis

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The type V transforming growth factor beta receptor is the putative insulin-like growth factor-binding protein 3 receptor

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Cellular internalization of insulin-like growth factor binding protein-3: distinct endocytic pathways facilitate re-uptake and nuclear localization

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Rapid apoptosis induction by IGFBP-3 involves an insulin-like growth factor-independent nucleomitochondrial translocation of RXRalpha/Nur77.

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Direct functional interactions between insulin-like growth factor-binding protein-3 and retinoid X receptor-alpha regulate transcriptional signaling and apoptosis

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Type Iα collagen is an IGFBP-3 binding protein

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Insulin-like growth factor binding protein-3 (IGFBP-3) in the prostate and in prostate cancer: local production, distribution and secretion pattern indicate a role in stromal-epithelial interaction

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IGFBP-3 is a metastasis suppression gene in prostate cancer

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The importance of metal ions for the formation and isolation of insulin-like growth factor-binding protein 3-transferrin (IGFBP-3-Tf) complexes, and the analysis of their physiological involvement

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IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms

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Specific metabolic biomarkers as risk and prognostic factors in colorectal cancer.

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Detection and identification of oxidized insulin-like growth factor-binding proteins and receptors in patients with colorectal carcinoma.

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Basal colon crypt cells are more sensitive than surface cells toward hydrogen peroxide, a factor of oxidative stress

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Interaction of insulin-like growth factor II (IGF-II) with multiple plasma proteins: high affinity binding of plasminogen to IGF-II and IGF-binding protein-3.

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Altered iron metabolism, transferrin receptor 1 and ferritin in patients with colon cancer

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Nuclear import of insulin-like growth factor-binding protein-3 and -5 is mediated by the importin beta subunit

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Insulin-like growth factor binding protein 3 (IGFBP-3) potentiates TRAIL-induced apoptosis of human colorectal carcinoma cells through inhibition of NF-kappaB.

1 reference

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Perspectives in mammalian IGFBP-3 biology: local vs. systemic action

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Identifiers

10.1016/J.YEXMP.2015.03.035

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Europe PubMed Central

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4 March 2020

1 reference

Europe PubMed Central

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4 March 2020

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