(Q87166084)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24464270%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

Assessment of physical stability of an antibody drug conjugate by higher order structure analysis: impact of thiol- maleimide chemistry (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24464270%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

author name string

Jianxin Guo

1

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6 March 2020

Sandeep Kumar

2

1 reference

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6 March 2020

Amarnauth Prashad

3

1 reference

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6 March 2020

Jason Starkey

4

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6 March 2020

Satish K Singh

5

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6 March 2020

publication date

24 January 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24464270%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

published in

Pharmaceutical Research

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6 March 2020

volume

31

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6 March 2020

issue

7

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6 March 2020

page(s)

1710-1723

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Fluorescent molecular rotors: a new class of probes for tubulin structure and assembly

6 March 2020

cites work

1 reference

12 December 2020

Solution behavior of IFN-beta-1a: an empirical phase diagram based approach

1 reference

12 December 2020

Stability of helix-rich proteins at high concentrations

1 reference

12 December 2020

The Protein Data Bank

1 reference

12 December 2020

Contribution of linker stability to the activities of anticancer immunoconjugates

1 reference

12 December 2020

Identification of amino acid residues responsible for the release of free drug from an antibody-drug conjugate utilizing lysine-succinimidyl ester chemistry

1 reference

12 December 2020

Nonnative aggregation of an IgG1 antibody in acidic conditions, part 2: nucleation and growth kinetics with competing growth mechanisms

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12 December 2020

Fluorescent molecular rotors as dyes to characterize polysorbate-containing IgG formulations

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12 December 2020

Investigation of protein conformational stability employing a multimodal spectrometer

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12 December 2020

Detection and characterization of aggregates, prefibrillar amyloidogenic oligomers, and protofibrils using fluorescence spectroscopy

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12 December 2020

Opalescence of an IgG2 monoclonal antibody solution as it relates to liquid-liquid phase separation

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12 December 2020

Reduction-alkylation strategies for the modification of specific monoclonal antibody disulfides

1 reference

12 December 2020

Using empirical phase diagrams to understand the role of intramolecular dynamics in immunoglobulin G stability

1 reference

12 December 2020

Derivative absorbance spectroscopy and protein phase diagrams as tools for comprehensive protein characterization: a bGCSF case study

1 reference

12 December 2020

Increased aggregation propensity of IgG2 subclass over IgG1: role of conformational changes and covalent character in isolated aggregates

1 reference

12 December 2020

Atomic structures of amyloid cross-beta spines reveal varied steric zippers

1 reference

12 December 2020

Effects of solvent polarity and solvent viscosity on the fluorescent properties of molecular rotors and related probes

1 reference

12 December 2020

Effects of drug loading on the antitumor activity of a monoclonal antibody drug conjugate

1 reference

12 December 2020

Arming antibodies: prospects and challenges for immunoconjugates

1 reference

12 December 2020

Comparative Effects of pH and Ionic Strength on Protein–Protein Interactions, Unfolding, and Aggregation for IgG1 Antibodies

1 reference

12 December 2020

High throughput thermostability screening of monoclonal antibody formulations

1 reference

12 December 2020

Tyrosine, phenylalanine, and disulfide contributions to the circular dichroism of proteins: circular dichroism spectra of wild-type and mutant bovine pancreatic trypsin inhibitor

1 reference

12 December 2020

Targeted cancer therapy: conferring specificity to cytotoxic drugs

1 reference

12 December 2020

Structure of the cross-beta spine of amyloid-like fibrils

1 reference

12 December 2020

A biophysical characterization of the peptide drug pramlintide (AC137) using empirical phase diagrams

1 reference

12 December 2020

Tunable degradation of maleimide-thiol adducts in reducing environments

1 reference

12 December 2020

Environment-sensitive behavior of fluorescent molecular rotors

1 reference

12 December 2020

Molecular origins of surfactant-mediated stabilization of protein drugs.

1 reference

12 December 2020

Contribution of variable domains to the stability of humanized IgG1 monoclonal antibodies.

1 reference

12 December 2020

Aggregation in protein-based biotherapeutics: computational studies and tools to identify aggregation-prone regions

1 reference

12 December 2020

Computational methods to predict therapeutic protein aggregation

1 reference

12 December 2020

Physicochemical stability of the antibody-drug conjugate Trastuzumab-DM1: changes due to modification and conjugation processes

1 reference

12 December 2020

Physical stability of proteins in aqueous solution: mechanism and driving forces in nonnative protein aggregation

1 reference

12 December 2020

Conformational stability and aggregation of therapeutic monoclonal antibodies studied with ANS and Thioflavin T binding

1 reference

12 December 2020

Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design

1 reference

12 December 2020

Analytical methods for physicochemical characterization of antibody drug conjugates

1 reference

12 December 2020

10.1007/S11095-013-1274-2

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24464270%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference